OTAVA-BB 1129464

Product Name: OTAVA-BB 1129464
CAS No.: 90868-92-1
Chemical Name: OTAVA-BB 1129464
Synonyms: OTAVA-BB 1129464;a-Cyclopropyl-4-bromo-benzylamine;alpha-Cyclopropyl-4-broMo-benzylaMine;(4-BROMOPHENYL)(CYCLOPROPYL)METHANAMINE;4-Bromo-α-cyclopropylbenzenemethanamine;Benzenemethanamine, 4-bromo-α-cyclopropyl-;1-(4-bromophenyl)-1-cyclopropylmethanamine;1-CYCLOPROPYL-1-(4-BROMOPHENYL)METHYLAMINE;Benzenemethanamine, 4-bromo-alpha-cyclopropyl-
CBNumber: CB72464021
Molecular Formula: C10H12BrN
Formula Weight: 226.116
MOL File: 90868-92-1.mol

More

Less

OTAVA-BB 1129464 Property

Boiling point:: 305.7±17.0 °C(Predicted)
Density: 1.486±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 9.09±0.10(Predicted)
Appearance: Colorless to light yellow Liquid

More

Less

Safety

HS Code: 2921490090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: HCH0345631
Product name: (4-BROMOPHENYL)(CYCLOPROPYL)METHYLAMINE
Purity: 95.00%
Packaging: 0.25G
Price: $233
Updated: 2021/12/16

AK Scientific

Product number: 5132AC
Product name: (4-Bromophenyl)(cyclopropyl)methanamine
Packaging: 250mg
Price: $471
Updated: 2021/12/16

Apolloscientific

Product number: OR451108
Product name: a-Cyclopropyl-4-bromo-benzylamine
Packaging: 1g
Price: $1158
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3630-9-12
Product name: a-Cyclopropyl-4-bromobenzylamine
Packaging: 1g
Price: $1277
Updated: 2021/12/16

Ambeed

Product number: A319648
Product name: (4-Bromophenyl)(cyclopropyl)methanamine
Purity: 95%
Packaging: 1g
Price: $587
Updated: 2021/12/16

More

Less

OTAVA-BB 1129464 Chemical Properties,Usage,Production

Synthesis

623-00-7

23719-80-4

90868-92-1

A solution of 4-bromobenzonitrile (6.30 g) in tetrahydrofuran (50 mL) was added dropwise to an ice-bath-cooled 0.5 M cyclopropylmagnesium bromide tetrahydrofuran solution (200 mL) over 20 minutes. The reaction mixture was stirred continuously for 5.5 hours under ice bath conditions. Subsequently, methanol (100 mL) was added slowly over 20 minutes to quench the reaction. After batchwise addition of sodium borohydride (2.65 g), the reaction mixture was gradually warmed to room temperature and stirred overnight. Upon completion of the reaction, saturated aqueous NaHCO3 was added and the pH of the mixture was adjusted to 8-9 with 1 M hydrochloric acid.The reaction mixture was extracted with dichloromethane and the organic phases were combined, washed with water and dried over anhydrous magnesium sulfate. The organic phase was concentrated under reduced pressure to give the crude product as an oil. The oil was redissolved in dichloromethane and extracted with 1 M hydrochloric acid. The combined aqueous phases were alkalized to pH 8-9 with 4M NaOH aqueous solution and extracted again with dichloromethane. The combined organic phases were washed with water and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to give α-cyclopropyl-4-bromobenzylamine as an oily product. Yield: 5.56 g (72% yield); mass spectrum (ESI+): m/z = 209/211 (Br)[M+H-NH3]+.

References

[1] Patent: WO2010/139673, 2010, A1. Location in patent: Page/Page column 80; 81
[2] Patent: WO2017/156179, 2017, A1. Location in patent: Paragraph 00404; 00405; 00406

OTAVA-BB 1129464 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

OTAVA-BB 1129464 Suppliers

China 22 India 1 United Kingdom 1 United States 2 Global 26

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

LABTER PHARMATECH(BEIJING) CO.,LTD

Tel: 010-56330744 18310155299
Fax: 010-56330744
Email: sales@labter.com.cn
Country: China
ProdList: 20000
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai CR Corporation Limited

Tel: 13062833949; 4006653949 4006653949
Fax: QQ: 2136646215
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 9755
Advantage: 58

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Bejing Famous Pharmaceutical Technology Co., Ltd.

Tel: 13331045123
Fax: 86-10-80339217
Email: 2559355526@qq.com
Country: China
ProdList: 14193
Advantage: 58

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126 15697568815;
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 20000
Advantage: 58

Baimei Jihua (Henan) Pharmaceutical Technology Co., Ltd

Tel: 037188900765 18037465274
Fax: QQ3430974218
Email: enyawanglei@sina.cn
Country: China
ProdList: 13966
Advantage: 58

Zhengzhou Radium Biotechnology Co. LTD

Tel: 19903857099
Fax: QQ: 2865126155
Email: sales@graybio.com
Country: China
ProdList: 2955
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-025-85560043 17301488900
Fax: 025-85563444
Email: info@synzest.com
Country: China
ProdList: 9286
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 18351873721
Email: helen.zhang@synzest.com
Country: China
ProdList: 8295
Advantage: 58

Hebei Boxin Biotechnology Co. , Ltd.

Tel: 19131160546
Email: 2681315246@qq.com
Country: China
ProdList: 13199
Advantage: 58

Nanjing Bic Biotechnology Co., Ltd

Tel: 025-58906079 17352406906
Email: sales@bicbiotech.com
Country: China
ProdList: 5996
Advantage: 58

Tianjin Xinkangyou Biotechnology Co., LTD

Tel: 19922659386
Email: niuli@tjxkys.cn
Country: China
ProdList: 2995
Advantage: 58

tianjinlinchenkejiyouxiangongsi

Tel: 15122256084 15122256084
Email: zhujianlin01@163.com
Country: China
ProdList: 2388
Advantage: 58

BEIJING ECHIRAL MED TECH DVLP

Tel: 18010053931
Email: echiral@126.com
Country: China
ProdList: 8298
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Nanjing Bicbiotechnology Co., Ltd

Tel: +86-2552131256 +86-18251840740
Email: sales@bicbiotech.com
Country: China
ProdList: 5994
Advantage: 58

90868-92-1, OTAVA-BB 1129464Related Search:

N-Ethyl-4-bromobenzylamine (3-bromo-2-fluorophenyl)methanamine (4-BROMOBENZYL)METHYLAMINE N-(4-bromobenzyl)-N-cyclopropylamine N-(TERT-BUTOXYCARBONYL)-2-BROMOBENZYLAMINE N-Methyl-4-bromobenzylamine Hydrochloride 2-Bromobenzylamine hydrochloride (3-BROMOBENZYL)METHYLAMINE tert-Butyl 4-bromo-2-methylbenzylcarbamate P-bromobenzylamine hydrochloride (1S)(3,4-DIBROMOPHENYL)CYCLOPROPYLMETHYLAMINE OTAVA-BB 1129464 (1R)(3,4-DIBROMOPHENYL)CYCLOPROPYLMETHYLAMINE 1-((4-bromophenyl)(cyclopropyl)methyl)hydrazine (1S)(4-BROMO-3-NITROPHENYL)CYCLOPROPYLMETHYLAMINE (1R)(4-BROMO-2-FLUOROPHENYL)CYCLOPROPYLMETHYLAMINE (1S)(4-BROMO-2-FLUOROPHENYL)CYCLOPROPYLMETHYLAMINE (1R)(4-BROMO-3-NITROPHENYL)CYCLOPROPYLMETHYLAMINE

(4-BROMOPHENYL)(CYCLOPROPYL)METHANAMINE

1-CYCLOPROPYL-1-(4-BROMOPHENYL)METHYLAMINE

Benzenemethanamine, 4-bromo-alpha-cyclopropyl-

a-Cyclopropyl-4-bromo-benzylamine

OTAVA-BB 1129464

alpha-Cyclopropyl-4-broMo-benzylaMine

1-(4-bromophenyl)-1-cyclopropylmethanamine

Benzenemethanamine, 4-bromo-α-cyclopropyl-

4-Bromo-α-cyclopropylbenzenemethanamine

90868-92-1