1-(5-Bromo-2-fluoropyridin-3-yl)ethanone
- Product Name
- 1-(5-Bromo-2-fluoropyridin-3-yl)ethanone
- CAS No.
- 1111637-74-1
- Chemical Name
- 1-(5-Bromo-2-fluoropyridin-3-yl)ethanone
- Synonyms
- 3-Acetyl-5-bromo-2-fluoropyridine;3-Acetyl-5-bromo-2-fluoropyridine 98%;1-(5-Bromo-2-fluoro-3-pyridyl)ethanone;1-(5-Bromo-2-fluoro-3-pyridinyl)ethanone;1-(5-Bromo-2-fluoropyridin-3-yl)ethanone;1-(5-BroMo-2-fluoropyridine-3-yl)ethanone;Ethanone, 1-(5-broMo-2-fluoro-3-pyridinyl)-;1-(5-Bromo-2-fluoropyridin-3-yl)ethan-1-one
- CBNumber
- CB72471472
- Molecular Formula
- C7H5BrFNO
- Formula Weight
- 218.03
- MOL File
- 1111637-74-1.mol
1-(5-Bromo-2-fluoropyridin-3-yl)ethanone Property
- Boiling point:
- 284.3±40.0 °C(Predicted)
- Density
- 1.619±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- solid
- pka
- -4.58±0.20(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- PHB00150
- Product name
- 1-(5-Bromo-2-fluoropyridin-3-yl)ethanone
- Purity
- AldrichCPR
- Packaging
- 1 g
- Price
- $113
- Updated
- 2025/07/31
- Product number
- B700455
- Product name
- 1-(5-Bromo-2-fluoropyridin-3-yl)ethanone
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- CS-0042075
- Product name
- 1-(5-Bromo-2-fluoropyridin-3-yl)ethan-1-one
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- PC7516
- Product name
- 3-Acetyl-5-bromo-2-fluoropyridine
- Purity
- 98%
- Packaging
- 1g
- Price
- $85
- Updated
- 2021/12/16
- Product number
- 4H17-B-X1
- Product name
- 3-Acetyl-5-bromo-2-fluoropyridine
- Packaging
- 1g
- Price
- $110
- Updated
- 2021/12/16
1-(5-Bromo-2-fluoropyridin-3-yl)ethanone Chemical Properties,Usage,Production
Synthesis
1111637-73-0
1111637-74-1
The general procedure for the synthesis of 1-(5-bromo-2-fluoro-3-pyridinyl)ethanone from the compound (CAS:1111637-73-0) was as follows: pyridinium dichromate (55.4 g, 147 mmol) was dissolved in dichloromethane (DCM, 100 mL) and the solution was cooled to 0 °C. Subsequently, a solution of 1-(5-bromo-2-fluoropyridin-3-yl)ethanol (10.8 g, 49.1 mmol) in DCM (30 mL) was added to this solution. The reaction mixture was gradually warmed to room temperature and stirred continuously for 48 hours. Upon completion of the reaction, the mixture was filtered through diatomaceous earth, the filter cake was washed with DCM and the filtrate was concentrated to afford 1-(5-bromo-2-fluoropyridin-3-yl)ethanone (11 g, 51 mmol, 100% yield) as a light yellow solid. Analyzed by LC/MS (ESI+), m/z = 218 (M + H+) was measured.
References
[1] Patent: US2014/213581, 2014, A1. Location in patent: Paragraph 0684
[2] Patent: WO2016/123629, 2016, A1. Location in patent: Paragraph 0214
[3] Patent: WO2009/16460, 2009, A2. Location in patent: Page/Page column 54
[4] Patent: US2014/107109, 2014, A1. Location in patent: Page/Page column
[5] Patent: US2014/107109, 2014, A1. Location in patent: Page/Page column
1-(5-Bromo-2-fluoropyridin-3-yl)ethanone Preparation Products And Raw materials
Raw materials
Preparation Products
1-(5-Bromo-2-fluoropyridin-3-yl)ethanone Suppliers
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- sales@apolloscientific.co.uk
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- United Kingdom
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View Lastest Price from 1-(5-Bromo-2-fluoropyridin-3-yl)ethanone manufacturers
- Product
- 1-(5-Bromo-2-fluoropyridin-3-yl)ethanone 1111637-74-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 200g
- Release date
- 2020-02-01