ChemicalBook > CAS DataBase List > (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one

Product Name
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
CAS No.
123367-26-0
Chemical Name
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
Synonyms
Imatinib impurity J;Irutinib Impurity A;(E)-3-(dimethylamino);Imatinib EP impuritiesA;Imatinib Mesilate Impurity A;Imatinib Mesilate EP Impurity A;Nilotinib Impurity 16 (Imatinib EP Impurity A);Imatinib EP Impurity A (Nilotinib Impurity 16);(E)-3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one;(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
CBNumber
CB72516261
Molecular Formula
C10H12N2O
Formula Weight
176.22
MOL File
123367-26-0.mol
More
Less

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Property

Melting point:
113℃
Boiling point:
281℃
Density 
1.070
Flash point:
124℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
4.74±0.70(Predicted)
color 
Dark Brown to Very Dark Brown
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TRC
Product number
D462115
Product name
(2E)​-​3-​(Dimethylamino)​-​1-​(3-​pyridyl)​prop-​2-​en-​1-​one
Packaging
250mg
Price
$50
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-DW
Product name
(2E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Purity
98.0%
Packaging
250mg
Price
$65
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-DW
Product name
(2E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Purity
98.0%
Packaging
1g
Price
$95
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-DW
Product name
(2E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Purity
98.0%
Packaging
5G
Price
$295
Updated
2021/12/16
Alichem
Product number
123367260
Product name
(E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Packaging
500g
Price
$296.8
Updated
2021/12/16
More
Less

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Chemical Properties,Usage,Production

Description

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one is a pharmaceutical intermediate used as an intermediate of nilotinib, a targeted anticancer drug for the treatment of chronic myeloid leukaemia (CML).

Uses

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one acts as a reagent for the synthesis of oxindole-linked indolyl-pyrimidine derivatives which are potential cytotoxic agents.

Solubility in organics

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one is soluble in chloroform and dichloromethane.

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Suppliers

Belgium 1 China 83 Finland 2 Germany 1 India 3 United Kingdom 1 United States 12 Global 103
Key Organics Ltd.
Tel
--
Fax
--
Email
info@keyorganics.net
Country
United Kingdom
ProdList
6741
Advantage
50
More
Less

View Lastest Price from (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one manufacturers

Career Henan Chemical Co
Product
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one 123367-26-0
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2019-12-25

123367-26-0, (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-oneRelated Search:

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine 2-Propen-1-one, 1-[(3R)-3-[4-amino-7-oxido-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]- Imatinib Impurity 38 Ibrutinib Impurity 28 (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone Imatinib Impurity 4 Ibrutinib Impurity 5 Ibrutinib Dimer Impurity Imatinib Impurity 7 (S)-Ibrutinib (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one 1-Piperidinecarboxylic acid, 3-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-, 1,1-diMethylethyl ester, (3R)- N-(2-Methyl-4-nitrophenyl)-4-(3-pyridinyl)-2-pyrimidinamine N-DESMETHYL IMATINIB 4-Chloromethyl-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide Ilutinib Methylxanthate Impurity C Ibrutinib Impurity D N-(3-GUANIDINO-4-METHYLPHENYL)-4-(METHYLPIPERAZINE-1-YL-METHYL)BENZAMIDE

  • (2E)-3-(DiMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one
  • (2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one (IMpurity of Nilotinib)
  • (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
  • (E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
  • Imatinib EP Impurity A (Nilotinib Impurity 16)
  • Nilotinib Impurity 16 (Imatinib EP Impurity A)
  • Imatinib impurity 14/(E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
  • (E)-3-(dimethylamino)
  • Nilotinib IMpurity ((2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one)
  • Irutinib Impurity A
  • Imatinib impurity J
  • 2-Propen-1-one, 3-(dimethylamino)-1-(3-pyridinyl)-, (2E)-
  • (E)-3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one
  • Imatinib EP impuritiesA
  • Imatinib Mesilate Impurity A
  • (2E)-3-(Dimethylamino)-1-(3-Pyridyl)prtop-2-en-1-one
  • Imatinib Mesilate EP Impurity A
  • 123367-26-0