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SC-1

Product Name
SC-1
CAS No.
1313019-65-6
Chemical Name
SC-1
Synonyms
SC-1;Compound SC-1;SC-1 >=98% (HPLC);1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-(4-cyanophenoxy)phenyl]-urea;Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-[4-(4-cyanophenoxy)phenyl]-;1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea, 10 mM in DMSO;STAT,cyclin-D1,Inhibitor,inhibit,kinase,Apoptosis,1(4Chloro3(trifluoromethyl)phenyl)3(4(4cyanophenoxy)phenyl)urea,p-STAT3,orally,anticancer,SHP-1,1 (4 Chloro 3 (trifluoromethyl)phenyl) 3 (4 (4 cyanophenoxy)phenyl)urea,survivin
CBNumber
CB72520383
Molecular Formula
C21H13ClF3N3O2
Formula Weight
431.8
MOL File
1313019-65-6.mol
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SC-1 Property

storage temp. 
2-8°C
solubility 
DMSO: soluble15mg/mL, clear
form 
powder
color 
white to beige
Water Solubility 
Water: Insoluble
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0858
Product name
SC-1
Purity
≥98% (HPLC)
Packaging
5mg
Price
$104
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0858
Product name
SC-1
Purity
≥98% (HPLC)
Packaging
25mg
Price
$409
Updated
2023/01/07
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SC-1 Chemical Properties,Usage,Production

Biological Activity

SC-1 is a derivative of the multiple tyrosine kinase inhibitor sorafenib with no kinase-inhibition activity. SC-1 blocks STAT3 phosphorylation and activation with similar potency to sorafenib, and induces apoptosis in hepatocellular carcinoma cell lines.

SC-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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SC-1 Suppliers

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1313019-65-6, SC-1Related Search:

BNL CL.2 G-Olig2 SC-43 4-ThiazolecarboxaMide, N-(6-benzoyl-1H-benziMidazol-2-yl)-2-(1-thieno[3,2-d]pyriMidin-4-yl-4-piperidinyl)- SC-560 4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile

  • SC-1
  • N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-(4-cyanophenoxy)phenyl]-urea
  • Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-[4-(4-cyanophenoxy)phenyl]-
  • SC-1 >=98% (HPLC)
  • 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
  • STAT,cyclin-D1,Inhibitor,inhibit,kinase,Apoptosis,1(4Chloro3(trifluoromethyl)phenyl)3(4(4cyanophenoxy)phenyl)urea,p-STAT3,orally,anticancer,SHP-1,1 (4 Chloro 3 (trifluoromethyl)phenyl) 3 (4 (4 cyanophenoxy)phenyl)urea,survivin
  • Compound SC-1
  • 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea, 10 mM in DMSO
  • 1313019-65-6
  • C21H13ClF3N3O2