3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo-
- Product Name
- 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo-
- CAS No.
- 957205-14-0
- Chemical Name
- 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo-
- Synonyms
- Br-PEG5-OH;HO-PEG5-Br;CAS_957205-14-0;Bromo-PEG5-alcohol;Reaxys ID: 26537424;14-bromo-3,6,9,12-tetraoxatetradecan-1-ol;3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo-;2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethanol;Br-PEG5-OH/3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo-
- CBNumber
- CB72522877
- Molecular Formula
- C10H21BrO5
- Formula Weight
- 301.17
- MOL File
- 957205-14-0.mol
3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DCM
- form
- Liquid
- color
- Colorless to light yellow
Safety
- HS Code
- 2942000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- BP-21691
- Product name
- Bromo-PEG5-alcohol
- Purity
- 98%
- Packaging
- 250mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- AS103997
- Product name
- Br-PEG5-OH
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $258
- Updated
- 2021/12/16
- Product number
- BP-21691
- Product name
- Bromo-PEG5-alcohol
- Purity
- 98%
- Packaging
- 500mg
- Price
- $390
- Updated
- 2021/12/16
- Product number
- AS103997
- Product name
- Br-PEG5-OH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $530
- Updated
- 2021/12/16
- Product number
- BP-21691
- Product name
- Bromo-PEG5-alcohol
- Purity
- 98%
- Packaging
- 1g
- Price
- $640
- Updated
- 2021/12/16
3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- Chemical Properties,Usage,Production
Description
Bromo-PEG5-alcohol is a PEG linker containing a bromide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Uses
Bromo-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- Preparation Products And Raw materials
Raw materials
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View Lastest Price from 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- manufacturers
- Product
- Br-PEG5-OH 957205-14-0
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-25