5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline

Product Name: 5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline
CAS No.: 1062174-44-0
Chemical Name: 5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline
Synonyms: Indoline-5-boronic Acid Pinacol Ester;INDOLIN-5-YLBORONIC ACID PINACOL ESTER;5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline;5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-indole;1H-Indole, 2,3-dihydro-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
CBNumber: CB72549791
Molecular Formula: C14H20BNO2
Formula Weight: 245.13
MOL File: 1062174-44-0.mol

More

Less

5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline Property

Boiling point:: 372.7±31.0 °C(Predicted)
Density: 1.08±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 4.59±0.20(Predicted)
Appearance: White to yellow Solid

More

Less

Safety

HS Code: 2933998090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: T305745
Product name: 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indoline
Packaging: 100mg
Price: $220
Updated: 2021/12/16

AK Scientific

Product number: X8796
Product name: 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indoline
Packaging: 250mg
Price: $277
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BOR0006939
Product name: 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)INDOLINE
Purity: 95.00%
Packaging: 5MG
Price: $502.32
Updated: 2021/12/16

Apolloscientific

Product number: OR305261
Product name: 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-indole
Packaging: 250mg
Price: $507
Updated: 2021/12/16

Matrix Scientific

Product number: 076396
Product name: 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indoline
Purity: 95+%
Packaging: 250mg
Price: $786
Updated: 2021/12/16

More

Less

5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline Chemical Properties,Usage,Production

Synthesis

837392-67-3

1062174-44-0

Step 3: tert-butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)dihydroindole-1-carboxylate (120 mg, 0.35 mmol) was dissolved in dichloromethane (5 mL), 2,2,2-trifluoroacetic acid (1 mL) was added, and the reaction mixture was stirred for 2 hours at room temperature. After the reaction was completed, it was neutralized with saturated aqueous sodium bicarbonate solution to pH=8 and then extracted with dichloromethane. The organic phases were combined, washed with brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford the target product 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)dihydroindole (74 mg, 87% yield).1H NMR (CDCl3) δ: 7.56 (1H, s), 7.50 (1H, d, J = 8.0 Hz), 6.60 (1H, d, J = 8.0 Hz), 3.57 (2H, t, J = 8.8 Hz), 3.02 (2H, t, J = 8.8 Hz), 1.32 (12H, s).

References

[1] Patent: WO2012/103806, 2012, A1. Location in patent: Page/Page column 48

5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline Suppliers

China 52 India 1 United Kingdom 1 United States 4 Global 58

Wuhan TCASChem Technology Co., Ltd.

Tel: 027-86697669 13986148687
Fax: 86-027-86697669
Email: sales@tcaschem.com
Country: China
ProdList: 3992
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

Shanghai Taifu Pharmaceutical Technology Co. LTD

Tel: 021-58111238 18930958102
Fax: 021-58111238
Email: sales@taifupharm.com
Country: China
ProdList: 509
Advantage: 55

Shanghai Balmxy Pharmaceutical Co., Ltd

Tel: 021-24206007 13764915196
Fax: 86-021-23027023
Email: sales@balmxy.com
Country: China
ProdList: 6874
Advantage: 55

ShangHai AmK Pharmaceutical Technology Co., Ltd.

Tel: 微信 17321281695 18019252918
Fax: 17321281695
Email: sale@amkchem.com
Country: China
ProdList: 15136
Advantage: 55

JW & Y Pharmlab Co., Ltd.

Tel: 021-64340559 13651849907;
Fax: 021- 64345308
Email: xinyu_shi@jwypharmlab.com.cn
Country: China
ProdList: 12000
Advantage: 58

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 0512-0512-52358471 17715136450
Fax: 05125235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 12127
Advantage: 58

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

1062174-44-0, 5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indolineRelated Search:

2,3-dihydro-1H-indol-6-ylmethanol 2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE 4-Methoxycarbonyl-2,3-dihydro-1H-indoline 2,3-DIHYDROINDOL-5-OL Indoline 1H-Indol-7-amine,2,3-dihydro-(9CI) 2,3-DIHYDRO-1H-INDOLE-4-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE Indoline-2-carboxylic acid

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-indole

1H-Indole, 2,3-dihydro-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-

5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)indoline

INDOLIN-5-YLBORONIC ACID PINACOL ESTER

Indoline-5-boronic Acid Pinacol Ester

1062174-44-0