Methylnissolin
- Product Name
- Methylnissolin
- CAS No.
- 73340-41-7
- Chemical Name
- Methylnissolin
- Synonyms
- Medicarpi;3-Hydroxy-9;Methylnissolin;Astrapterocarpan;Methylnissolin, 10 mM in DMSO;METHYLNISSOLIN (ASTRAPTEROCARPAN);3-Hydroxy-9,10-dimethoxyptercarpan;L-3-Hydroxy-9,10-dimethoxylpterocarpan;3-Hydroxy-9,10-dimethoxyptercarpanMedicarpin;3-Hydroxy-9,10-dimethoxyptercarpan,Methylnissolin
- CBNumber
- CB72589627
- Molecular Formula
- C17H16O5
- Formula Weight
- 300.31
- MOL File
- 73340-41-7.mol
Methylnissolin Property
- Boiling point:
- 428.9±45.0 °C(Predicted)
- Density
- 1.312
- storage temp.
- 4°C, protect from light
- solubility
- Acetone: soluble; Chloroform: soluble; Dichloromethane: soluble; DMSO: soluble; Ethyl Acetate: soluble
- form
- A solid
- pka
- 9.44±0.20(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- CS-0022755
- Product name
- Methylnissolin
- Purity
- 99.53%
- Packaging
- 1mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- CS-0022755
- Product name
- Methylnissolin
- Purity
- 99.53%
- Packaging
- 5mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- CS-0022755
- Product name
- Methylnissolin
- Purity
- 99.53%
- Packaging
- 10mg
- Price
- $760
- Updated
- 2021/12/16
- Product number
- CD11065301
- Product name
- 3-Hydroxy-9,10-dimethoxyptercarpan
- Purity
- 97%
- Packaging
- 25mg
- Price
- $979
- Updated
- 2021/12/16
- Product number
- 4325
- Product name
- Methylnissolin
- Packaging
- 20mg
- Price
- $1090
- Updated
- 2021/12/16
Methylnissolin Chemical Properties,Usage,Production
Chemical Properties
It is a white crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It is derived from Astragalus membranaceus (Fisch.) Bunge.
Uses
Methylnissolin (Astrapterocarpan), isolated from Astragalus membranaceus, inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase. Methylnissolin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibition of the ERK1/2 MAP kinase cascade[1].
Definition
ChEBI: Astrapterocarpan is a member of pterocarpans.
IC 50
PDGFR: 10 μM (IC50); ERK1; ERK2
References
[1] Ohkawara S, et al. Astrapterocarpan isolated from Astragalus membranaceus inhibits proliferation of vascular smooth muscle cells. Eur J Pharmacol. 2005 Nov 21;525(1-3):41-7. DOI:10.1016/j.ejphar.2005.08.063
Methylnissolin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methylnissolin manufacturers
- Product
- Methylnissolin 73340-41-7
- Price
- US $0.00/mg
- Min. Order
- 10mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-02
- Product
- (-)-6aR,11aR-dihydro-3-hydroxy-9,10-dimethoxy-6H-benzofuro[3,2-c][1]-benzopyran 73340-41-7
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-09