Methyl 3-broMo-6-chloropyrazine-2-carboxylate Property

Melting point:

35-36 °C

Boiling point:

292.4±35.0 °C(Predicted)

Density 

1.772±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

pka

-3.78±0.10(Predicted)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

Methyl 3-broMo-6-chloropyrazine-2-carboxylate Chemical Properties,Usage,Production

Uses

Methyl 3-broMo-6-chloropyrazine-2-carboxylate is an important intermediate for the synthesis of a class of antitumour drugs, SHP2 inhibitors, which can be used in the pharmaceutical development process.