Edoxaban tosylate

Product Name: Edoxaban tosylate
CAS No.: 480449-71-6
Chemical Name: Edoxaban tosylate
Synonyms: DU-176b;Edoxaban TsOH;Edoxaban tosylate;Edoxaban (TsOH salt);Edoxaban p-Toluenesulfonate;Edoxaban tosylate (DU-176b);9H-FLUORENE-2,11-DICARBOXYLICACID;C24H30ClN7O4S.C7H7HSO3 Edoxaban (TsOH salt) 480449-71-6;N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide;N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide 4-methylbenzenesulfonate
CBNumber: CB72627790
Molecular Formula: C24H30ClN7O4S.C7H8O3S
Formula Weight: 720.26
MOL File: 480449-71-6.mol

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Edoxaban tosylate Property

storage temp.: Store at -20°C
solubility: 25℃: DMSO
form: Powder
color: White to off-white
InChIKey: ZLFZITWZOYXXAW-BUZWFPPCNA-N
SMILES: S(C1C=CC(C)=CC=1)(O)(=O)=O.N([C@@H]1C[C@@H](C(=O)N(C)C)CC[C@@H]1NC(=O)C(=O)NC1N=CC(Cl)=CC=1)C(C1SC2CN(C)CCC=2N=1)=O |&1:12,14,22,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3263
Product name: Edoxaban tosylate
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $74.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML3263
Product name: Edoxaban tosylate
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $360
Updated: 2025/07/31

Cayman Chemical

Product number: 24030
Product name: Edoxaban (tosylate)
Purity: ≥98%
Packaging: 500μg
Price: $33
Updated: 2024/03/01

Cayman Chemical

Product number: 24030
Product name: Edoxaban (tosylate)
Purity: ≥98%
Packaging: 1mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 24030
Product name: Edoxaban (tosylate)
Purity: ≥98%
Packaging: 5mg
Price: $238
Updated: 2024/03/01

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Edoxaban tosylate Chemical Properties,Usage,Production

Uses

Edoxaban tosylate (Lixiana; Daiichi Sankyo, Tokyo, Japan), known as DU-176b in clinical trials, is a novel oral direct factor Xa inhibitor. Edoxaban has good bioavailability with maximum plasma concentration achieved 1–2 h after ingestion and plasma half-life of 8–10 h. Edoxaban is a novel anticoagulant (NOAC) indicated to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis and pulmonary embolism.

Definition

ChEBI: An organosulfonate salt obtained by combining equimolar amounts of edoxaban and 4-toluenesulfonic acid. Used (in the form of its monohydrate) for the treatment of deep vein thrombosis and pulmonary embolism.

in vivo

Edoxaban tosylate (0.5, 2.5 and 12.5 mg/kg; p.o.; once) significantly and dose-dependently reduces the thrombus formation and prolongs PT^[1].

Animal Model:	Male Slc: Wistar rats (210-240 g); Male New Zealand White rabbits(2.5-3.5 kg) (Both are venous stasis thrombosis model)^[1].
Dosage:	0.5, 2.5 and 12.5 mg/kg
Administration:	Oral administration; once
Result:	Inhibited exogenous FXa activity. Antithrombotic.

Edoxaban tosylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Edoxaban tosylate Suppliers

China 134 India 6 United Kingdom 1 United States 6 Global 147

Zhejiang Jiuzhou Pharmaceutical Co., Ltd

Tel: 13566413511
Email: le.sun@jiuzhoupharma.com
Country: China
ProdList: 35
Advantage: 58

Changzhou Joyous Chemical Co., Ltd.

Tel: 0519-85607258 13912342323;
Fax: 0519-85607278
Email: sales@joyouschem.com
Country: China
ProdList: 294
Advantage: 60

Shanghai Arbor Chemical Co., Ltd.

Tel: 021-60451683 15021268886
Fax: +86-21-60451682
Email: sales@arborchemical.com
Country: China
ProdList: 896
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
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Advantage: 55

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Nanjing Credit Trading Co.,Ltd

Tel: 025-52164950
Fax: 025-86800069
Email: Googlexu_0114@sina.com
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Finetech Industry Limited

Tel: 027-87465837 19945049750
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Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 18013166090
Fax: 0512-87182056
Email: lingling.qi@yacoo.com.cn
Country: China
ProdList: 6295
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Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

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View Lastest Price from Edoxaban tosylate manufacturers

Wuhan JiyunZen Tech Co., Ltd.

Product: Edoxaban tosylate 480449-71-6
Price: US $5.00-0.50/KG
Min. Order: 1KG
Purity: 99% hplc
Supply Ability: 500TONS
Release date: 2025-06-05

ZHUHAI HRD PHARMACEUTICAL CO., LTD.

Product: Edoxaban (tosylate) 480449-71-6
Price: US $0.00/kg Ton
Min. Order: 1kg Ton
Purity: 99%+
Supply Ability: 2 tons/month
Release date: 2022-10-09

Hangzhou Huarong Pharm Co., Ltd.

Product: Edoxaban tosylate 480449-71-6
Price: US $0.00-0.00/KG
Min. Order: 100g
Purity: 99%
Supply Ability: 500KG
Release date: 2021-09-15

480449-71-6, Edoxaban tosylateRelated Search:

Edoxaban tosylate monohydrate EthanediaMide iMpurity F EthanediaMide iMpurity F hcl Edoxaban Impurity 19 (1S,2R,4S) Mesylate lithium 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate EthanediaMide iMpurity D EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2S,4S)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- Tert-Butyl(1R,2S,5S)-2-azido-5-[(dimethylamino)carbonyl]cyclohexylcarbamate oxalic acid edoxaban Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride tert-butyl (1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexylcarbaMate

Edoxaban TsOH

DU-176b

Edoxaban (TsOH salt)

Edoxaban tosylate

Edoxaban tosylate (DU-176b)

C24H30ClN7O4S.C7H7HSO3 Edoxaban (TsOH salt) 480449-71-6

9H-FLUORENE-2,11-DICARBOXYLICACID

Edoxaban p-Toluenesulfonate

N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide

N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide 4-methylbenzenesulfonate

N-(5-Chloropyridin-2-yl)-N′-((1S,2R,4S)-4-[(dimethyl amino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl)ethanediamide p-toluenesulfonate

Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate (1:1)

480449-71-6

480448-71-6

824193-20-8

C24H30ClN7O4SC7H7HSO3

C31H38ClN7O7S2

C24H30ClN7O4SC7H8O3S