Valsartan D9
- Product Name
- Valsartan D9
- CAS No.
- 1089736-73-1
- Chemical Name
- Valsartan D9
- Synonyms
- [2H9]-Valsartan;rac-Valsartan D9;Cefuroxime Impurity 73;[2H9]-Valsartan (mixture);ACWBQPMHZXGDFX-KDDXQTGLSA-N;VALSARTAN-D9 (D7-D9 MIXTURE);L-Valine, N-(1-oxopentyl-d9)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-;(2S)-3-methyl-2-[2,2,3,3,4,4,5,5,5-nonadeuteriopentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid;Valsartan D9Q: What is Valsartan D9 Q: What is the CAS Number of Valsartan D9 Q: What is the storage condition of Valsartan D9 Q: What are the applications of Valsartan D9
- CBNumber
- CB72640030
- Molecular Formula
- C24H29N5O3
- Formula Weight
- 435.53
- MOL File
- 1089736-73-1.mol
Valsartan D9 Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
- form
- A solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H361Suspected of damaging fertility or the unborn child
H402Harmful to aquatic life
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 25226
- Product name
- Valsartan-d9
- Purity
- ≥99% deuterated forms (d1-d9)
- Packaging
- 1mg
- Price
- $364
- Updated
- 2024/03/01
- Product number
- V095753
- Product name
- Valsartan-d9(Major)
- Packaging
- 1mg
- Price
- $190
- Updated
- 2021/12/16
- Product number
- 2885DC
- Product name
- ValsartanD9
- Packaging
- 1mg
- Price
- $503
- Updated
- 2021/12/16
- Product number
- BAR0001573
- Product name
- VALSARTAN-D9
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $837.38
- Updated
- 2021/12/16
- Product number
- BAR0001573
- Product name
- VALSARTAN-D9
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $2656.5
- Updated
- 2021/12/16
Valsartan D9 Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
An isotopically labelled version of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
Biological Activity
Valsartan-d9 is intended for use as an internal standard for the quantification of valsartan by GC- or LC-MS. Valsartan is a nonpeptide antagonist of the angiotensin II type 1 (AT1) receptor (IC50 = 2.7 nM). It is 20,000-fold selective for AT1 over AT2 and, unlike some other AT receptor antagonists, does not alter peroxisome proliferator-activated receptor γ (PPARγ) activity in vitro. In vivo, valsartan (30 mg/kg) increases cardiac output and reduces left ventricular fibrosis in a model of heart failure with reduced ejection fraction in mice with streptozotocin-induced diabetes. Formulations containing valsartan have been used in the treatment of hypertension and heart failure.