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Valsartan D9

Product Name
Valsartan D9
CAS No.
1089736-73-1
Chemical Name
Valsartan D9
Synonyms
[2H9]-Valsartan;rac-Valsartan D9;D9-Valsartan(major);2H9]-Valsartan(major);Cefuroxime Impurity 73;[2H9]-Valsartan (mixture);ACWBQPMHZXGDFX-KDDXQTGLSA-N;VALSARTAN-D9 (D7-D9 MIXTURE);L-Valine, N-(1-oxopentyl-d9)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-;(2S)-3-methyl-2-[2,2,3,3,4,4,5,5,5-nonadeuteriopentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
CBNumber
CB72640030
Molecular Formula
C24H29N5O3
Formula Weight
435.53
MOL File
1089736-73-1.mol
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Valsartan D9 Property

storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
form 
A solid
color 
White to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H361Suspected of damaging fertility or the unborn child

H402Harmful to aquatic life

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
25226
Product name
Valsartan-d9
Purity
≥99% deuterated forms (d1-d9)
Packaging
1mg
Price
$364
Updated
2024/03/01
TRC
Product number
V095753
Product name
Valsartan-d9(Major)
Packaging
1mg
Price
$190
Updated
2021/12/16
AK Scientific
Product number
2885DC
Product name
ValsartanD9
Packaging
1mg
Price
$503
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BAR0001573
Product name
VALSARTAN-D9
Purity
95.00%
Packaging
1MG
Price
$837.38
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BAR0001573
Product name
VALSARTAN-D9
Purity
95.00%
Packaging
10MG
Price
$2656.5
Updated
2021/12/16
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Valsartan D9 Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

An isotopically labelled version of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.

Biological Activity

Valsartan-d9 is intended for use as an internal standard for the quantification of valsartan by GC- or LC-MS. Valsartan is a nonpeptide antagonist of the angiotensin II type 1 (AT1) receptor (IC50 = 2.7 nM). It is 20,000-fold selective for AT1 over AT2 and, unlike some other AT receptor antagonists, does not alter peroxisome proliferator-activated receptor γ (PPARγ) activity in vitro. In vivo, valsartan (30 mg/kg) increases cardiac output and reduces left ventricular fibrosis in a model of heart failure with reduced ejection fraction in mice with streptozotocin-induced diabetes. Formulations containing valsartan have been used in the treatment of hypertension and heart failure.

IC 50

AT1 Receptor

Valsartan D9 Preparation Products And Raw materials

Raw materials

Preparation Products

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Valsartan D9 Suppliers

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1089736-73-1, Valsartan D9Related Search:

Valsartan Acid Isopropyl Ester Valsartan valsartan Valsartan-d8 VALSARTAN-D3 KAZCQVXZLKDFCA-NDEPHWFRSA-N Telmisartan Impurity 10 BOC-D-4,4'-BIPHENYLALANINE 1426129-50-1 enantioMer (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate methyl N-valeryl-N-[(2'-cyanobiphenyl-4-yl)methyl]-L-valinate Valsartan Impurity 10 N-[2’-(1H-tetrazol-5-yl)biphenyl-4-yl methyl]-N-Valeryl-(L)-Valine methyl ester Valsartan Impurity 12 ethyl N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-N-pentanoyl-L-valinate Valsartan Desvaleryl Impurity Valsartan n-Propyl 4-Bromomethyl-2-cyanobiphenyl

  • L-Valine, N-(1-oxopentyl-d9)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-
  • ACWBQPMHZXGDFX-KDDXQTGLSA-N
  • (2S)-3-methyl-2-[2,2,3,3,4,4,5,5,5-nonadeuteriopentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
  • rac-Valsartan D9
  • [2H9]-Valsartan (mixture)
  • [2H9]-Valsartan
  • VALSARTAN-D9 (D7-D9 MIXTURE)
  • Valsartan D9Q: What is Valsartan D9 Q: What is the CAS Number of Valsartan D9 Q: What is the storage condition of Valsartan D9 Q: What are the applications of Valsartan D9
  • 2H9]-Valsartan(major)
  • Cefuroxime Impurity 73
  • (2S)-3-methyl-2-(N-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}(2,2,3,3,4,4,5,5,5-2H?)pentanamido)butanoic acid
  • D9-Valsartan(major)
  • 1089736-73-1