4-Boc-2-(broMoMethyl)Morpholine
- Product Name
- 4-Boc-2-(broMoMethyl)Morpholine
- CAS No.
- 765914-78-1
- Chemical Name
- 4-Boc-2-(broMoMethyl)Morpholine
- Synonyms
- 4-Boc-broMoMethylMorpholine;4-Boc-2-(broMoMethyl)Morpholine;n-boc-(2)-(broMoMethyl)Morpholine;tert-butyl 2-(broMoMethyl)Morpholine-4-carboxylate;2-Bromomethylmorpholine-4-carboxylic acid tert-butyl ester;4-Morpholinecarboxylic acid, 2-(bromomethyl)-, 1,1-dimethylethyl ester
- CBNumber
- CB72651737
- Molecular Formula
- C10H18BrNO3
- Formula Weight
- 280.16
- MOL File
- 765914-78-1.mol
4-Boc-2-(broMoMethyl)Morpholine Property
- Boiling point:
- 328.8±32.0 °C(Predicted)
- Density
- 1.334±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- -2.34±0.40(Predicted)
- Appearance
- White to yellow Solid
Safety
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- AS3686
- Product name
- N-Boc-(2)-(Bromomethyl)morpholine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $308
- Updated
- 2021/12/16
- Product number
- HCH0365482
- Product name
- 4-BOC-2-(BROMOMETHYL)MORPHOLINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.42
- Updated
- 2021/12/16
- Product number
- AS3686
- Product name
- N-Boc-(2)-(Bromomethyl)morpholine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $620
- Updated
- 2021/12/16
- Product number
- 093665
- Product name
- 4-Boc-2-(bromomethyl)morpholine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $756
- Updated
- 2021/12/16
- Product number
- 4H56-9-5R
- Product name
- 4-Boc-2-(bromomethyl)morpholine
- Packaging
- 1g
- Price
- $1440
- Updated
- 2021/12/16
4-Boc-2-(broMoMethyl)Morpholine Chemical Properties,Usage,Production
Synthesis
135065-69-9
765914-78-1
To a solution of tert-butyl 2-(hydroxymethyl)morpholine-4-carboxylate (0.67 g, 3.1 mmol) in dichloromethane (35 mL) was added carbon tetrabromide (CBr4, 2.06 g, 6.17 mmol) at -20 °C, followed by the slow dropwise addition of a solution of triphenylphosphine (PPh3, 1.70 g, 6.48 mmol) in dichloromethane (25 mL). The reaction mixture was maintained at -15 °C for 18 h, and subsequently brought to room temperature with continued stirring for 1.5 h. The reaction was carried out under reduced pressure. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the residue was purified by silica gel column chromatography (eluent: ethyl acetate/hexane) to afford the target product tert-butyl 2-(bromomethyl)morpholine-4-carboxylate 0.55 g in 63% yield, which was used directly in the subsequent reaction.
References
[1] Patent: WO2007/58850, 2007, A2. Location in patent: Page/Page column 44
4-Boc-2-(broMoMethyl)Morpholine Preparation Products And Raw materials
Raw materials
Preparation Products
4-Boc-2-(broMoMethyl)Morpholine Suppliers
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- United Kingdom
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- enquiries@fluorochem.co.uk
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- United Kingdom
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