ChemicalBook > CAS DataBase List > 1,6-Dihydroxyeriolanolide

1,6-Dihydroxyeriolanolide

Product Name: 1,6-Dihydroxyeriolanolide
CAS No.: 33620-72-3
Chemical Name: 1,6-Dihydroxyeriolanolide
Synonyms: Deacetylinulicin;Desacetylinulicin;1,6-Dihydroxyeriolanolide;Britannilactone (Desacetylinulicin);2(3H)-Benzofuranone, 3a,4,7,7a-tetrahydro-4-hydroxy-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-, (3aS,4S,7aR)-
CBNumber: CB72654112
Molecular Formula: C15H22O4
Formula Weight: 266.33
MOL File: 33620-72-3.mol

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1,6-Dihydroxyeriolanolide Property

Melting point:: 175.1-177.0℃
Boiling point:: 477.4±45.0 °C(Predicted)
Density: 1.17±0.1 g/cm3 (20 ºC 760 Torr)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Cryst.
pka: 13.71±0.60(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Crysdot

Product number: CD31002194
Product name: Britannilactone
Purity: 98+%
Packaging: 5mg
Price: $179
Updated: 2021/12/16

Arctom

Product number: CFN92601
Product name: Britannilactone
Packaging: 10mg
Price: $318
Updated: 2021/12/16

Crysdot

Product number: CD31002194
Product name: Britannilactone
Purity: 98+%
Packaging: 10mg
Price: $319
Updated: 2021/12/16

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1,6-Dihydroxyeriolanolide Chemical Properties,Usage,Production

Uses

Britannilactone(Desacetylinulicin) is a methanol extract of the dried flower of Inula britannica L. IC50 value: Target: A bioassay-guided isolation of the chloroform fraction of the I. britannica using an in vitro melanogenesis inhibition assay led to the isolation of sesquiterpenes, 1-O-acetylbritannilactone (1), britannilactone (2) and neobritannilactone B (3). Compounds 1 and 2 significantly reduced melanin production in a dose-dependent manner with IC50 values of 13.3 and 15.5 μM, respectively [1].

References

[1] Choo SJ, et al. Hypo-pigmenting effect of sesquiterpenes from Inula britannica in B16 melanoma cells. Arch Pharm Res. 2014 May;37(5):567-74. DOI:10.1007/s12272-013-0302-4

1,6-Dihydroxyeriolanolide Preparation Products And Raw materials

Raw materials

Preparation Products

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33620-72-3, 1,6-DihydroxyeriolanolideRelated Search:

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1,6-Dihydroxyeriolanolide

Deacetylinulicin

Britannilactone (Desacetylinulicin)

Desacetylinulicin

2(3H)-Benzofuranone, 3a,4,7,7a-tetrahydro-4-hydroxy-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-, (3aS,4S,7aR)-

33620-72-3