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Temephos

Product Name
Temephos
CAS No.
3383-96-8
Chemical Name
Temephos
Synonyms
temefos;ABATE;Abat;Difos;lypor;Ecopro;oms786;swebat;Bithion;cl52160
CBNumber
CB7265792
Molecular Formula
C16H20O6P2S3
Formula Weight
466.47
MOL File
3383-96-8.mol
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Temephos Property

Melting point:
30-31°C
Boiling point:
518.5±60.0 °C(Predicted)
Density 
1.3200
vapor pressure 
9.5×10-6Pa (20-25 °C)
storage temp. 
2-8°C
solubility 
DMSO : ≥ 100 mg/mL (214.38 mM)
form 
solid
color 
Colorless to light yellow
Water Solubility 
0.003 g/100 mL
Merck 
13,9214
BRN 
1896901
InChI
InChI=1S/C16H20O6P2S3/c1-17-23(25,18-2)21-13-5-9-15(10-6-13)27-16-11-7-14(8-12-16)22-24(26,19-3)20-4/h5-12H,1-4H3
InChIKey
WWJZWCUNLNYYAU-UHFFFAOYSA-N
SMILES
P(=S)(OC)(OC)OC1C=CC(SC2C=CC(OP(=S)(OC)OC)=CC=2)=CC=1
CAS DataBase Reference
3383-96-8(CAS DataBase Reference)
NIST Chemistry Reference
Temefos(3383-96-8)
EPA Substance Registry System
Temephos (3383-96-8)
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Safety

Hazard Codes 
Xn,N
Risk Statements 
21/22-51/53
Safety Statements 
22-37-61-60
RIDADR 
UN 3077
OEB
B
OEL
TWA: 10 mg/m3 (total)
WGK Germany 
3
RTECS 
TF6890000
HazardClass 
6.1
PackingGroup 
III
Hazardous Substances Data
3383-96-8(Hazardous Substances Data)
Toxicity
LD50 in male, female rats (mg/kg): 8600, 13000 orally (Gaines)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H311Toxic in contact with skin

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
31526
Product name
Temephos
Purity
PESTANAL?, analytical standard
Packaging
250mg
Price
$117
Updated
2024/03/01
TRC
Product number
T017250
Product name
Temephos
Packaging
10g
Price
$1055
Updated
2021/12/16
AK Scientific
Product number
O510
Product name
Temephos
Packaging
250mg
Price
$126
Updated
2021/12/16
Biorbyt Ltd
Product number
orb595226
Product name
ABAT
Packaging
10μg
Price
$290.7
Updated
2021/12/16
Biorbyt Ltd
Product number
orb595227
Product name
ABAT
Packaging
10μg
Price
$574.6
Updated
2021/12/16
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Temephos Chemical Properties,Usage,Production

Description

Abate is the trade name for Temephos, the known organophosphate larvicide. Abate is used to treat water infested with disease-carrying fleas and control mosquito, midge, and black fly larvae. Abate quickly controls mosquito and other insect populations because it kills insect larvae before they mature, and the residual activity of abate prevents insect populations. On decomposition, abate produces oxides of carbon, phosphorous, and sulphur. Exposures to abate in workplaces cause adverse health effects (refer to Temephos for details).

Chemical Properties

Temephos is a solid at room temperature and is composed of colorless crystals. As a liquid, it is brown and viscous. Temephos is a non-systemic insecticide. It is insoluble in water, hexane, and methyl cyclohexane, but soluble in common organic solvents. It is combustible and the liquid formulations contain organic solvents that may be flammable. Temophos decomposes on heating or burning, producing toxic fumes such as phosphorus oxides and sulfur oxides. Temephos reacts with strong acids and strong bases. The US EPA has grouped temephos as a GUP. Temephos is used for the control of mosquito, midge, and black fl y larvae. It is used in lakes, ponds, and wetlands. It may also be used to control fl eas on dogs and cats and to control lice on humans.

Uses

Temephos is used to control mosquito and black fly larvae in aqueous environments and as a human and veterinary ectoparasiticide.

Uses

Temephos is an organophosphate larvicide used to treat water infested with disease-carrying insects.

Definition

ChEBI: Temephos is an organic sulfide that is diphenyl sulfide in which the hydrogen at the para position of each of the phenyl groups has been replaced by a (dimethoxyphosphorothioyl)oxy group. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an acaricide, an agrochemical and an ectoparasiticide. It is an organic thiophosphate, an organothiophosphate insecticide and an organic sulfide. It is functionally related to a 4,4'-thiodiphenol.

General Description

White crystalline solid or liquid. Boiling point 87°F. Used as an insecticide. Technical grade is a viscous brown liquid.

Reactivity Profile

Organothiophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Hazard

Cholinesterase inhibitor. Questionable carcinogen.

Health Hazard

Abate is less toxic in comparison to withmost other organophosphorus pesticides.Among the test animals, rats showedalmost 10 times greater resistance to thiscompound than did mice and rabbits.In humans, ingestion can cause nausea,vomiting, diarrhea, and convulsions. Intakeof large amounts can result in respiratoryfailure.
LD50 value, oral (rats): 8600 mg/kg.

Health Hazard

Exposures to high concentrations of temephos for a prolonged period of time cause poisoning to occupational workers. The symptoms include, but are not limited to, nausea, salivation, headache, loss of muscle coordination, and diffi culty breathing. Workers exposed to a combination of temephos and malathion suffer potentiation of toxicity of temephos. Exposures to granules of temephos formulation may cause irritation. Prolonged and repeated skin contact may cause irritation. Inhalation may cause respiratory irritation and chemical pneumonities. There are no reports on the prolonged effects of temephos.

Health Hazard

to avoid contamination of water, food, or feed, abate should be stored in a secure, dry,

Agricultural Uses

Insecticide, Larvicide: Temephos is one of the few organophosphates that is registered to control mosquito larvae. It is a non-systemic insecticide for use on wetlands, ponds, lakes and other moist areas to control mosquito, gnat, black fly, midge, pinkie and sandfly larvae. Banned for use in EU countries[ 115]. Registered for use in the U.S.

Trade name

27165®; ABAT®; ABATE®; ABATE® 1-SG; ABATE® 2-CG; ABATE® 4-E; ABATE® 5CG; ABATHION®; AI3-27165®; AC 52160®; AMERICAN CYANAMID AC-52,160®; AMERICAN CYANAMID CL-52160®; AMERICAN CYANAMID E. I.52,160®; BIOTHION®; BITHION®; CL 52160®; DIFENPHOS®; DIFENTHOS®; DIFOS®; DIPHOS®; ECOPRO®; ECOPRO® 1707; EI 52160®; NEPHIS®; NEPHIS® 1G; NIMITEX®; NIMITOX®

Safety Profile

Posion by ingestion Moderately toxic by intraperitoneal, subcutaneous, and skin contact routes. An experimental teratogen. A skin irritant. A cholinesterase inhibitor type of insecticide. When heated to decomposition it emits toxic fumes of POx and SOx. See also PARATHION,

Carcinogenicity

The EPA noted a chronic dog study (period of exposure not specified) in which significant inhibition of plasma and RBC cholinesterase occurred at dietary exposures equivalent to 12.5 mg/kg/day but not at 0.46 mg/kg/day .
No evidence of carcinogenicity or other treatment-related effects occurred in rats fed a diet that contained 0, 10, 100, or 300 ppm temephos (equivalent to about 0.5, 5.0, or 15 mg/kg/ day) for 2 years . The animals in the treated groups were exposed in utero from gestation day 12 through parturition to 100 ppm of the test material, and at weaning pups were randomly allocated to the three treatment groups and the treatment initiated.

Metabolic pathway

Temephos is comparatively stable to metabolic degradation in both animals and plants. The main pathway is via thiooxidation to the sulfoxide and through hydrolysis to yield 4,4’-thiodiphenol and its thiooxidised derivatives which are conjugated as glucosides in plants and as sulfate esters in rats. Oxidative desulfuration to temephos oxon is apparently a minor pathway.

storage

During use and handling of abate, occupational workers/applicators should wear long- sleeved shirts, long pants, shoes, and socks, chemical-resistant gloves, and protective eyewear, goggles, or safety glasses. Flaggers must wear chemical-resistant headgear and protective eyewear.

Degradation

Temephos is hydrolysed by strong acids and alkalis; its maximum stability is at pH 5-7 (PM). When a methanolic solution of temephos was exposed to sunlight it was rapidly decomposed resulting in the formation of at least eight photoproducts of which only temephos sulfoxide (2) and temephos sulfone (3) were identified. The sulfoxide was the major initial product but it was further photolysed to the sulfone (3) which was apparently refractory to further degradation suggesting that the other unidentified photoproducts arose directly from temephos or from the sulfoxide (2) (Rosen, 1972) (Scheme 1).

Toxicity evaluation

Temephos has a very low mammalian toxicity; acute oral LD50 for male and female rats is 4204 and >10,000 mg/kg, respectively. NOEL (2 yr) for rats is 300 mg/kg diet (15 mg/kg/d). Temephos administered orally to rats is eliminated in the feces and urine. The major elimination compound is unchanged temephos. Other urinary metabolites are sulfate ester conjugates of 4,4 -thiodiphenol, its sulfoxide, and sulfone.

Temephos Preparation Products And Raw materials

Raw materials

Preparation Products

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Temephos Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
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Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
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Tianjin Derchemist Science & Technology Co., Ltd.
Tel
22-58627059 13920586291
Fax
022-58620305
Email
zdcomcon@126.com
Country
China
ProdList
3461
Advantage
50
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
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View Lastest Price from Temephos manufacturers

Career Henan Chemical Co
Product
Temephos 3383-96-8
Price
US $3.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
200KG
Release date
2020-01-07

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