ChemicalBook > CAS DataBase List > 1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine

1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine

Product Name
1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine
CAS No.
1089279-91-3
Chemical Name
1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine
Synonyms
1-(4-amino-3-methoxyphenyl)-N,N-dimethyl-4-Piperidinamine;1-(4-amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine;4-Piperidinamine, 1-(4-amino-3-methoxyphenyl)-N,N-dimethyl-;1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine;1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine - [A16491]
CBNumber
CB72677386
Molecular Formula
C14H23N3O
Formula Weight
249.35
MOL File
1089279-91-3.mol
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1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine Property

Boiling point:
421.1±45.0 °C(Predicted)
Density 
1.10±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
9.28±0.20(Predicted)
Appearance
Light brown to brown Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
2141AQ
Product name
1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine
Packaging
5g
Price
$244.4
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM1053731
Product name
1-(4-AMINO-5-METHOXY-2-METHYLPHENYL)-N,N-DIMETHYLPIPERIDIN-4-AMINE
Purity
95.00%
Packaging
5MG
Price
$500.97
Updated
2021/12/16
AK Scientific
Product number
2141AQ
Product name
1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine
Packaging
25g
Price
$714.8
Updated
2021/12/16
Ambeed
Product number
A108946
Product name
1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine
Purity
96%
Packaging
100mg
Price
$9
Updated
2021/12/16
Ambeed
Product number
A108946
Product name
1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine
Purity
96%
Packaging
1g
Price
$36
Updated
2021/12/16
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1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine Chemical Properties,Usage,Production

Uses

1-(4-Amino-3-methoxyphenyl)-N,N-dimethyl-4-piperidinamine is a useful reagent for organic synthesis.

Synthesis

1089279-90-2

1089279-91-3

General procedure for the synthesis of 1-(4-amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine from BRIGATINIB intermediates: 4.09 g of Compound 29 was added to a reaction flask and dissolved with 40 mL of methanol. Subsequently, 0.4 g of 10% Pd/C catalyst (based on 10% of the mass of Compound 29) was added for the hydrogenation reduction reaction. The progress of the reaction was monitored by TLC and the reaction was complete after about 6 hours. After stopping the reaction, the reaction mixture was filtered and the catalyst was washed with a small amount of methanol. The filtrate was concentrated by distillation under reduced pressure to give 3.38 g of brown solid product 7-6 in 92.60% yield.

References

[1] Patent: CN106905245, 2017, A. Location in patent: Paragraph 0249; 0259; 0260; 0261; 0262
[2] Patent: KR2016/37844, 2016, A. Location in patent: Paragraph 0304; 0306
[3] Patent: EP3372594, 2018, A1. Location in patent: Paragraph 0126; 0128; 0264; 0265
[4] Patent: US2008/300242, 2008, A1. Location in patent: Page/Page column 86
[5] Patent: WO2010/138575, 2010, A1. Location in patent: Page/Page column 82

1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine Suppliers

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View Lastest Price from 1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
1-(4-amino-5-Methoxy-2-Methylphenyl)-N,N-dimethylpiperidin-4-amine 1089279-91-3
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-08-08
Shanghai CRM New Material Technology Co., LTD
Product
1-(4-amino-5-Methoxy-2-Methylphenyl)-N,N-dimethylpiperidin-4-amine 1089279-91-3
Price
US $10.00-15.00/g
Min. Order
10g
Purity
99%
Supply Ability
10t
Release date
2022-09-21
Career Henan Chemical Co
Product
1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine 1089279-91-3
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2019-12-24

1089279-91-3, 1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMineRelated Search:

Lithium bis(trimethylsilyl)amide Potassium bis(trimethylsilyl)amide

  • 1-(4-aMino-5-Methoxy-2-Methylphenyl)-N,N-diMethylpiperidin-4-aMine
  • 1-(4-amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine
  • 1-(4-amino-3-methoxyphenyl)-N,N-dimethyl-4-Piperidinamine
  • 4-Piperidinamine, 1-(4-amino-3-methoxyphenyl)-N,N-dimethyl-
  • 1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine - [A16491]
  • 1089279-91-3