Potassium bis(trimethylsilyl)amide

Product Name: Potassium bis(trimethylsilyl)amide
CAS No.: 40949-94-8
Chemical Name: Potassium bis(trimethylsilyl)amide
Synonyms: KHMDS;POTASSIUM HEXAMETHYLDISILAZIDE;HEXAMETHYLDISILAZANE POTASSIUM SALT;HMDS K;KHMDS 0.7M;PotassiumHMDS;Potassium bis(trimet;Potassium bis(trimethyL;potassiumhexamethyldisil;POTASSIUM HEXAMETHYLDISLAZANE
CBNumber: CB8139300
Molecular Formula: C6H18KNSi2
Formula Weight: 199.48
MOL File: 40949-94-8.mol

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Potassium bis(trimethylsilyl)amide Property

Melting point:: 194-195°C
Boiling point:: 111 °C
Density: 0.877 g/mL at 25 °C
vapor density: 3.2 (vs air)
vapor pressure: 54 mm Hg ( 25 °C)
refractive index: 1.4920
Flash point:: 45 °F
storage temp.: Refrigerator
solubility: Miscible with terahydrofuran, ether, benzene and toluene.
form: Liquid
Specific Gravity: 0.877
color: clear to slightly hazy yellow
Water Solubility: Reacts with water.
Hydrolytic Sensitivity: 8: reacts rapidly with moisture, water, protic solvents
Sensitive: Moisture Sensitive
BRN: 4006754
CAS DataBase Reference: 40949-94-8(CAS DataBase Reference)
EPA Substance Registry System: Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-, potassium salt (1:1) (40949-94-8)

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Safety

Hazard Codes: C,F,Xn
Risk Statements: 14-34-67-65-63-48/20-11-40-36/37/38-19-37
Safety Statements: 26-36/37/39-45-62-43-46-16-36/37
RIDADR: UN 3263 8/PG 3
WGK Germany: 3
F: 1-3-10
TSCA: No
HazardClass: 3
PackingGroup: II
HS Code: 29319090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 277304
Product name: Potassium bis(trimethylsilyl)amide solution
Purity: 0.5 M in toluene
Packaging: 4x25ml
Price: $91.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 277304
Product name: Potassium bis(trimethylsilyl)amide solution
Purity: 0.5 M in toluene
Packaging: 2l
Price: $880
Updated: 2024/03/01

TCI Chemical

Product number: H0893
Product name: Potassium Bis(trimethylsilyl)amide (11% in Toluene, ca. 0.5mol/L)
Packaging: 100mL
Price: $89
Updated: 2021/12/16

TCI Chemical

Product number: H0893
Product name: Potassium Bis(trimethylsilyl)amide (11% in Toluene, ca. 0.5mol/L)
Packaging: 500mL
Price: $268
Updated: 2021/12/16

Sigma-Aldrich

Product number: 775061
Product name: Potassium bis(trimethylsilyl)amide solution
Purity: 1.0 M in 2-methyltetrahydrofuran
Packaging: 4x25ml
Price: $327
Updated: 2024/03/01

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Potassium bis(trimethylsilyl)amide Chemical Properties,Usage,Production

Chemical Properties

Colorless to amber solution

Uses

Potassium Hexamethyldisilazide is widely used as a Sterically Hindered Base for Enolate Generation in Selective Formation of Linear Conjugated Dienolates and Alkyl (Z)-3-Alkenoates.

Uses

Potassium Bis(trimethylsilyl)amide (1M in THF) is used in the preparation of 5-azacytidine, an antineoplastic drug. Also applied in the preparation of β3-AR agonists used in anti-stress formulations. It is also used as a reagent in the preparation of lanthanide complexes employed in selective cyclization reactions.

Uses

Potassium bis(trimethylsilyl)amide is a strong base used in the alkylation carbonyl compounds.1

Preparation

Potassium Hexamethyldisilazide is prepared and isolated by the procedure of Wannagat and Niederpruem. A more convenient in situ generation from potassium hydride and hexamethyldisilane is described by Brown.

General Description

This product, 1.0 M in 2-methyltetrahydrofuran aligns with "Safer Solvents and Auxiliaries", "Use of Renewable Feedstocks" and "Inherently Safer Chemistry for Accident Prevention".

Potassium bis(trimethylsilyl)amide Preparation Products And Raw materials

Raw materials

Preparation Products

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Potassium bis(trimethylsilyl)amide Suppliers

Belgium 3 China 185 Europe 1 Germany 5 India 35 Italy 1 Japan 2 Singapore 1 Slovakia 1 South Korea 1 Switzerland 2 United Kingdom 11 United States 27 Global 275

Panjin Infinity Scientific CO. LTD

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J & K SCIENTIFIC LTD.

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Energy Chemical

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JinYan Chemicals(ShangHai) Co.,Ltd.

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View Lastest Price from Potassium bis(trimethylsilyl)amide manufacturers

airuikechemical co., ltd.

Product: potassium bis(trimethylsilyl)amide 40949-94-8
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99.9%
Supply Ability: 200tons
Release date: 2024-04-08

Zhuozhou Wenxi import and Export Co., Ltd

Product: Potassium bis(trimethylsilyl)amide 40949-94-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: Potassium hexamethyldisilazide 40949-94-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 25kg
Release date: 2019-07-09

40949-94-8, Potassium bis(trimethylsilyl)amideRelated Search:

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