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S1RA (hydrochloride)

Product Name
S1RA (hydrochloride)
CAS No.
1265917-14-3
Chemical Name
S1RA (hydrochloride)
Synonyms
177303;S1RA. HCL;S1RA HCl (E-52862);S1RA (E-52862) HCI;S1RA (hydrochloride);E52862 hydrochloride;E 52862 hydrochloride;E-52862 hydrochloride;E-52862 HYDROCHLORIDE;E52862 HYDROCHLORIDE;E 52862 HYDROCHLORIDE;4-(2-(5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy)ethyl)morpholine hydrochloride
CBNumber
CB72682021
Molecular Formula
C20H24ClN3O2
Formula Weight
373.88
MOL File
1265917-14-3.mol
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S1RA (hydrochloride) Property

storage temp. 
-20°C (des.)
solubility 
Soluble in DMSO (up to at least 25 mg/ml)
form 
solid
color 
Off-white
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-2188
Product name
S1RAhydrochloride
Purity
99.24%
Packaging
5mg
Price
$110
Updated
2021/12/16
ChemScene
Product number
CS-2188
Product name
S1RAhydrochloride
Purity
99.24%
Packaging
10mg
Price
$165
Updated
2021/12/16
Biosynth Carbosynth
Product number
BS177543
Product name
S1RA hydrochloride
Packaging
25mg
Price
$240
Updated
2021/12/16
Biosynth Carbosynth
Product number
BS177543
Product name
S1RA hydrochloride
Packaging
50mg
Price
$320
Updated
2021/12/16
ChemScene
Product number
CS-2188
Product name
S1RAhydrochloride
Purity
99.24%
Packaging
50mg
Price
$550
Updated
2021/12/16
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S1RA (hydrochloride) Chemical Properties,Usage,Production

Description

S1RA (E-52862, 1265917-14-3) is a potent and selective σ1 antagonist with weak binding at σ2?(IC50?σ1 = 17nM, σ2 = 9300nM).1,2?S1RA abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a σ1 dependent manner.3?S1RA potentiated μ-opioid antinociception in mice in a σ-dependent manner.4?S1RA displayed neuroprotective effects in a mouse model of ischemic stroke.5

References

References/Citations

S1RA (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

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S1RA (hydrochloride) Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
Advantage
55
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Biopharmaleader Co., Ltd.
Tel
+86 18721201413
Fax
+86 (21) 5775-8967
Email
sales@biopharmaleader.com
Country
China
ProdList
1720
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60

1265917-14-3, S1RA (hydrochloride)Related Search:


  • S1RA (hydrochloride)
  • 4-[2-[[5-Methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine hydrochloride (1:1)
  • 4-(2-(5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy)ethyl)morpholine hydrochloride
  • S1RA. HCL
  • E 52862 hydrochloride
  • E52862 hydrochloride
  • E-52862 hydrochloride
  • E-52862 HYDROCHLORIDE;E52862 HYDROCHLORIDE;E 52862 HYDROCHLORIDE
  • 177303
  • S1RA (E-52862) HCI
  • S1RA HCl (E-52862)
  • Inhibitor,E 52862,S1RA hydrochloride,E52862,S1RA,E-52862,inhibit,S-1RA hydrochloride,Sigma Receptor
  • 1265917-14-3
  • C20H23N3O2HCl