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EzetiMibe-d4

Product Name
EzetiMibe-d4
CAS No.
1093659-89-2
Chemical Name
EzetiMibe-d4
Synonyms
Ezetimibe-d4-1;[2H4]-Ezetimibe;Ezetimibe Impurity 119;Ezetimibe D4 (4-Fluorophenyl-2,3,5,6-d4);(3R,4S)-1-(4-fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)propyl]azetidin-2-one;Ezetimibe D4Q: What is Ezetimibe D4 Q: What is the CAS Number of Ezetimibe D4 Q: What is the storage condition of Ezetimibe D4
CBNumber
CB72710005
Molecular Formula
C24H21F2NO3
Formula Weight
409.43
MOL File
1093659-89-2.mol
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EzetiMibe-d4 Property

storage temp. 
Store at -20°C
solubility 
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form 
A solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
25044
Product name
Ezetimibe-d4
Purity
≥99% deuterated forms (d1-d4)
Packaging
1mg
Price
$480
Updated
2024/03/01
TRC
Product number
E975003
Product name
Ezetimibe-d4
Packaging
1mg
Price
$275
Updated
2021/12/16
AK Scientific
Product number
2934DC
Product name
(3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)propyl]azetidin-2-one
Packaging
1mg
Price
$633
Updated
2021/12/16
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EzetiMibe-d4 Chemical Properties,Usage,Production

Description

Ezetimibe-d4 is intended for use as an internal standard for the quantification of ezetimibe by GC- or LC-MS. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Upon oral administration ezetimibe undergoes rapid glucuronidation in the intestine where its glucuronide binds NPC1L1. Ezetimibe exhibits ED50 values of 0.0005-0.05 mg/kg in various animal models, selectively blocking cholesterol absorption without inhibiting pancreatic lipolytic enzyme activities in the intestinal lumen, affecting bile acid micelle solubilization of cholesterol, or interfering with the absorption of triglycerides, fatty acids, or bile acids.

Uses

Ezetimibe-d4 is the labeled analogue of Ezetimibe (E975000), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.

EzetiMibe-d4 Preparation Products And Raw materials

Raw materials

Preparation Products

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EzetiMibe-d4 Suppliers

China 21 India 3 United States 3 Global 27
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
ProdList
96815
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Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
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China
ProdList
32344
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50
Cato Research Chemicals Inc.
Tel
020-81960175
Fax
+1-541-2553641
Email
min.he@cato-chem.com
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China
ProdList
1958
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ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
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sales@chem-strong.com
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China
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17993
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Artis Biotech Co. Ltd.
Tel
19138486554 18582380095
Fax
0575-89298961
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sales@artisbio.com
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China
ProdList
2804
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58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
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021-65675885
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info@efebio.com
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China
ProdList
9709
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58
Chengdu Novel Biomedical Co., Ltd.
Tel
028-85255396 18302801538
Fax
028-85255396
Email
cdnovell@163.com
Country
China
ProdList
2251
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58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
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China
ProdList
55954
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
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sales@chemegen.com
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China
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11289
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58
Nanjing wangzhixing Pharmaceutical Technology Co., Ltd
Tel
15850510341
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025-85722793
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shiqingran@wzxchem.com
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China
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3567
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Hubei Xinyang Medical Technology Co., Ltd
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15347293736 15347293736
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QQ：2853117752
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2853117764@qq.com
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China
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8594
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Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
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China
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44843
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58
PureChemland Co.,Ltd.
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19150123681
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3848291069@qq.com
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China
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3258
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Nanjing Huanuo Biomedical Technology Co., Ltd
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18913906212
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2885426135@qq.com
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China
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6580
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Shanghai isotope chemical co.,ltd
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021-021-51600108 13062666369
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sales@chinaisotope.com
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China
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4272
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Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
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021-59167510 18117107507
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vip@med-life.cn
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China
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guoyungurui
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18162595016
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3287908757@qq.com
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China
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Nanjing Shizhou Biology Technology Co.,Ltd
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17301488900
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025-85560043
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judy.xia@synzest.com
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China
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12584
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Guangzhou Zhenlin Pharmaceutical Technology Co., Ltd
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18102736234 18102736234
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2208093734@qq.com
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China
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6348
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Nantong Hanfang Biotechnology Co. , Ltd.
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3674309880
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hanfangpharma@126.com
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China
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30968
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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--
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info@zzsrm.com
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CHINA
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6846
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1093659-89-2, EzetiMibe-d4Related Search:

Ezetimibe (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one EzetiMibe Fluoro IsoMer EZETIMIBE PHENOXY GLUCURONIDE (3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid N,N'-Diisopropylcarbodiimide (3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Ezetimibe Impurity 33 (S)-(+)-4-Phenyl-2-oxazolidinone 4-[[(4-Fluorophenyl)imino]methyl]-phenol (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one EzetiMibe Dehydoxy IMpurity Ezetimibe-13C6 (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one

  • (3R,4S)-1-(4-fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)propyl]azetidin-2-one
  • [2H4]-Ezetimibe
  • Ezetimibe Impurity 119
  • Ezetimibe D4Q: What is Ezetimibe D4 Q: What is the CAS Number of Ezetimibe D4 Q: What is the storage condition of Ezetimibe D4
  • Ezetimibe-d4-1
  • Ezetimibe D4 (4-Fluorophenyl-2,3,5,6-d4)
  • 1093659-89-2