TRYPSINOGEN
- Product Name
- TRYPSINOGEN
- CAS No.
- 9002-08-8
- Chemical Name
- TRYPSINOGEN
- Synonyms
- TRYPSINOGEN;Ttrypsinogen;TRYPSINOGEN FROM BEEF PANCREAS;trypsinogen from bovine pancreas;Trypsinogen >2500 U/mg from bovine;Trypsinogen >2500U/mg from bovine pancreas;Trypsinogen, PMSF treated from bovine pancreas
- CBNumber
- CB7282580
- Molecular Formula
- C39H55N9O17
- Formula Weight
- 921.9
- MOL File
- 9002-08-8.mol
TRYPSINOGEN Property
- storage temp.
- 2-8°C
- form
- essentially salt-free, lyophilized powder
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-42
- Safety Statements
- 22-24-26-36/37
- WGK Germany
- 3
- F
- 10-21
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T1143
- Product name
- Trypsinogen from bovine pancreas
- Purity
- essentially salt-free, lyophilized powder, ≥10,000?BAEE units/mg protein (E1%/280, after activation to trypsin)
- Packaging
- 250MG
- Price
- $212
- Updated
- 2023/06/20
- Product number
- T9011
- Product name
- Trypsinogen, PMSF treated from bovine pancreas
- Purity
- For use as a marker in SDS-PAGE
- Packaging
- 1VIAL
- Price
- $532
- Updated
- 2023/06/20
- Product number
- T1143
- Product name
- Trypsinogen from bovine pancreas
- Purity
- essentially salt-free, lyophilized powder, ≥10,000?BAEE units/mg protein (E1%/280, after activation to trypsin)
- Packaging
- 1G
- Price
- $695
- Updated
- 2023/06/20
TRYPSINOGEN Chemical Properties,Usage,Production
Uses
Trypsinogen from bovine pancreas is suitable for use in:
- the secondary structure analysis of proteins in H2O solution using single-pass attenuated total reflection Fourier transform infrared (ATR-FT-IR) microscopy
- tuning and calibration of electrospray ionization quadrupole time-of-flight (ESI-Q-TOF) mass spectrometer
- the secondary structure analysis of proteins by infrared (IR) spectroscopy
- SDS-PAGE as a molecular weight standard (24kDa)
General Description
Trypsinogen is a proenzyme (zymogen) that is activated to form trypsin. It is synthesized in the pancreas and activated by enterokinase once it reaches the lumen of the small intestine. Bovine trypsinogen is a single polypeptide chain of 229 amino acids that is cross linked by six disulfide bridges. Enterokinase cleaves a hexapeptide to from the NH2 terminus of trypsinogen at the Lys6 - Ile7 peptide bond and activates it. Trypsin, thus formed, autocatalytically activates more trypsinogen to trypsin. This native form of trypsin is called β-trypsin, which undergoes autolysis at Lys131 - Ser132 resulting in α-trypsin that is held together by disulfide bridges. Trypsin is a serine protease with His46 and Ser183 at the active site. The pH optimum of trypsin is 7 - 9.
Biochem/physiol Actions
Hereditary pancreatitis was shown to be caused by a Arg-His substitution at residue 117 of trypsinogen causing auto-activation of trypsinogen to trypsin.
TRYPSINOGEN Preparation Products And Raw materials
Raw materials
Preparation Products
TRYPSINOGEN Suppliers
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- 021-61415566 800-8193336
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- China
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- 010-010-010-62971590 18548936886
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- 15527250409
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- QQ：2692360204
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- 17691182729 18161915376
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- 13581502185
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