PLASMINOGEN
- Product Name
- PLASMINOGEN
- CAS No.
- 9001-91-6
- Chemical Name
- PLASMINOGEN
- Synonyms
- PROFIBRINOLYSIN;PLASMINOGEN, HUMAN;HUMAN GLU-PLASMINOGEN;PLASMINOGEN USP/EP/BP;PROFIBRINOLYSIN, HUMAN;GLU-PLASMINOGEN (HUMAN);PLASMA TRYPSINOGEN, HUMAN;PLASMINOGEN, HUMAN PLASMA;PLASMINOGEN, GLU-TYPE, HUMAN;plasminogen from horse plasma
- CBNumber
- CB6257448
- Molecular Formula
- NULL
- Formula Weight
- 0
- MOL File
- Mol file
PLASMINOGEN Property
- storage temp.
- -20°C
- form
- lyophilized powder
N-Bromosuccinimide Price
- Product number
- P9156
- Product name
- Plasminogen from bovine plasma
- Purity
- lyophilized powder, ≥2.0?units/mg protein
- Packaging
- 5units
- Price
- $390
- Updated
- 2024/03/01
- Product number
- P9156
- Product name
- Plasminogen from bovine plasma
- Purity
- lyophilized powder, ≥2.0?units/mg protein
- Packaging
- 25units
- Price
- $1400
- Updated
- 2024/03/01
- Product number
- P7999
- Product name
- Plasminogen from human plasma
- Purity
- ≥2.0?units/mg protein, lumps and powder, suitable for streptokinase determination by clot formation procedure
- Packaging
- 25units
- Price
- $504
- Updated
- 2024/03/01
- Product number
- P7999
- Product name
- Plasminogen from human plasma
- Purity
- ≥2.0?units/mg protein, lumps and powder, suitable for streptokinase determination by clot formation procedure
- Packaging
- 10units
- Price
- $578
- Updated
- 2024/03/01
- Product number
- 528178
- Product name
- Plasminogen, EACA- and Lysine-Free, Human Plasma
- Packaging
- 50u
- Price
- $464
- Updated
- 2024/03/01
PLASMINOGEN Chemical Properties,Usage,Production
Uses
Plasminogen is a single-chain glycoprotein found in human plasma and extracellular fluid. Certain activators, such as tissue plasminogen activator (tPA), convert plasminogen to its active form, plasmin. Plasminogen has been used to study its conversion into plasmin.
General Description
The plasminogen (PLG) gene is mapped to human chromosome 6q26. Plasminogen protein has a molecular weight of ?90kDa. It is composed of Pan-apple domain at the N-terminal, five kringle domains and serine protease domain at its C-terminal.
Biochem/physiol Actions
Plasminogen is the inactive precursor of the protease plasmin. Plasminogen is activated by the action of either tissue plasminogen activator (tPA), which primarily activates the fibrinolytic (thrombolytic) activity of plasmin, or urokinase plasminogen activator (uPA), which is associated with extracellular matrix remodeling and cell migration. Plasmin cleaves fibrin/fibrinogen and blood coagulation factors V/Va and VIII/VIIIa. It activates matrix metalloproteinases by cleaving the inactive proenzymes. It is also involved in the activation of some growth factors, such as vascular endothelial growth factor (VEGF) and transforming growth factor β (TGF-β).
PLASMINOGEN Preparation Products And Raw materials
Raw materials
Preparation Products
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