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8-Hydroxyquinoline sulfate

Product Name
8-Hydroxyquinoline sulfate
CAS No.
134-31-6
Chemical Name
8-Hydroxyquinoline sulfate
Synonyms
8-HYDROXYQUINOLINE SULPHATE;QUINOSOL;HYDROXYQUINOLINE SULFATE;8-HYDROXYQUINOLINE HEMISULFATE SALT;OXYQUINOLINE SULFATE;happy;albisal;octofen;sunoxol;khinozol
CBNumber
CB7284180
Molecular Formula
2C9H7NO.H2O4S
Formula Weight
388.4
MOL File
134-31-6.mol
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8-Hydroxyquinoline sulfate Property

Melting point:
~175 °C
Density 
1.3819 (rough estimate)
vapor pressure 
0Pa at 25℃
refractive index 
1.5364 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
crystalline
color 
yellow
Water Solubility 
>=10 g/100 mL at 19 ºC
Merck 
14,4843
BRN 
3760550
InChIKey
MRUMAIRJPMUAPZ-UHFFFAOYSA-N
LogP
2.42 at 25℃
CAS DataBase Reference
134-31-6(CAS DataBase Reference)
EPA Substance Registry System
8-Quinolinol sulfate (134-31-6)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
RIDADR 
2811
WGK Germany 
1
RTECS 
VC8260000
3-10
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1490103
Product name
Oxyquinoline sulfate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$424
Updated
2024/03/01
Sigma-Aldrich
Product number
55100
Product name
8-Quinolinol hemisulfate salt
Purity
≥98.0% (dry substance, T), yellow
Packaging
100g
Price
$182
Updated
2023/06/20
Sigma-Aldrich
Product number
55100
Product name
8-Quinolinol hemisulfate salt
Purity
≥98.0% (dry substance, T), yellow
Packaging
500g
Price
$400
Updated
2023/06/20
TCI Chemical
Product number
Q0017
Product name
8-Quinolinol Sulfate Monohydrate
Purity
>98.0%(T)
Packaging
25g
Price
$47
Updated
2024/03/01
TCI Chemical
Product number
Q0017
Product name
8-Quinolinol Sulfate Monohydrate
Purity
>98.0%(T)
Packaging
500g
Price
$389
Updated
2024/03/01
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8-Hydroxyquinoline sulfate Chemical Properties,Usage,Production

Chemical Properties

Crystalline

Originator

Chinosol,Chinosolfabrik

Uses

Pharmaceutic aid (complexing agent).

Uses

oxyquinoline sulfate is a disinfectant and a preservative against fungus growth. It is made from phenols.

Uses

8-Hydroxyquinoline sulfate is used to control grey mould (Botrytis cinevea) in vine grafting. It is also used as a soil sterilant against damping off in seed beds.

Manufacturing Process

The mixture of 1.4 kg o-nitrophenol, 2.1 kg o-aminophenol, 6 kg glycerine (d = 1.26) and 5 kg sulfuric acid (d = 1.848) was heated at reflux to temperature 130°-140°C. This temperature was kept for 1.5 hours. The obtained oxyquinoline precipitated, the liquid was removed with water-steam distillation. The residue was diluted with water and alkalized with sodium hydroxide and sodium carbonate to the strong alkaline reaction. The repeated distillation with water steam gave the oil, which hardened as the long needles by cooling. MP: 75°-76°C recrystallized from diluted ethanol.
In practice it is usually used as sulfate salt

Therapeutic Function

Antiseptic

General Description

Pale yellow to yellow crystalline powder with a slight saffron odor. Burning taste.

Air & Water Reactions

Water soluble.

Reactivity Profile

A sulfate acidic salt of an amine that is also a phenol. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Fire Hazard

Flash point data for 8-Hydroxyquinoline sulfate are not available, but 8-Hydroxyquinoline sulfate is probably combustible.

Flammability and Explosibility

Not classified

Metabolic pathway

Little published information is available.

Degradation

The salt and free base of 8-hydroxyquinoline sulfate are very stable but alkali liberates quinolin-8-ol which precipitates heavy metals (PM). 8-Hydroxyquinoline is a chelate ligand of transition metals such as copper.

8-Hydroxyquinoline sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 8-Hydroxyquinoline sulfate manufacturers

Henan Fengda Chemical Co., Ltd
Product
8-Hydroxyquinoline sulfate 134-31-6
Price
US $8.00-0.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28
Hebei Duling International Trade Co. LTD
Product
8-Hydroxyquinoline sulfate 134-31-6
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000 tons
Release date
2022-09-25
Hangzhou FandaChem Co.,Ltd.
Product
8-Hydroxyquinoline Sulfate 99% 134-31-6
Price
US $16.00/KG
Min. Order
1000KG
Purity
99%MIN
Supply Ability
1000 Tons
Release date
2018-01-04

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