1-TRIMETHYLSILYLMETHANOL

Product Name: 1-TRIMETHYLSILYLMETHANOL
CAS No.: 3219-63-4
Chemical Name: 1-TRIMETHYLSILYLMETHANOL
Synonyms: DK264;NSC 96777;rimethylsilylmethanol;(trimethylsilyl)-methano;1-TRIMETHYLSILYLMETHANOL;(TRIMETHYLSILYL)METHANOL;Methanol, (trimethylsilyl)-;TRIMETHYLHYDROXYMETHYLSILANE;Methanol,1-(trimethylsilyl)-;1-TRIMETHYLSILYLMETHANOL, 98+%
CBNumber: CB7284458
Molecular Formula: C4H12OSi
Formula Weight: 104.22
MOL File: 3219-63-4.mol

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1-TRIMETHYLSILYLMETHANOL Property

Melting point:: <0°C
Boiling point:: 120-122 °C754 mm Hg(lit.)
Density: 0.826 g/mL at 25 °C(lit.)
refractive index: n20/D 1.419(lit.)
Flash point:: 88 °F
storage temp.: 2-8°C
pka: 15.92±0.10(Predicted)
form: clear liquid
Specific Gravity: 0.827
color: Colorless to Almost colorless
Water Solubility: Fully miscible in water.
Hydrolytic Sensitivity: 1: no significant reaction with aqueous systems
BRN: 1731486
CAS DataBase Reference: 3219-63-4(CAS DataBase Reference)
EPA Substance Registry System: Methanol, (trimethylsilyl)- (3219-63-4)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: UN 1987 3/PG 3
WGK Germany: 3
RTECS: PC4100000
TSCA: Yes
HS Code: 2931.90.9010
HazardClass: 3
PackingGroup: III

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: T1250
Product name: Trimethylsilylmethanol
Purity: >97.0%(GC)
Packaging: 5mL
Price: $113
Updated: 2024/03/01

TCI Chemical

Product number: T1250
Product name: Trimethylsilylmethanol
Purity: >97.0%(GC)
Packaging: 25mL
Price: $389
Updated: 2024/03/01

Alfa Aesar

Product number: L04251
Product name: 1-Trimethylsilylmethanol, 95%
Packaging: 1g
Price: $37.65
Updated: 2024/03/01

Alfa Aesar

Product number: L04251
Product name: 1-Trimethylsilylmethanol, 95%
Packaging: 5g
Price: $156.65
Updated: 2024/03/01

Usbiological

Product number: 291767
Product name: Trimethylsilylmethanol
Packaging: 2g
Price: $313
Updated: 2021/12/16

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1-TRIMETHYLSILYLMETHANOL Chemical Properties,Usage,Production

Uses

1-Trimethylsilylmethanol is used as nucleophile to resolve the racemate obtained from enantioselective esterification of naproxen (2-(6-methoxy-2-naphthyl) propionic acid) by lipases. It was also used as a nucleophilic hydroxymethylation agent.

Purification Methods

If the NMR indicates impurities (should have only two signals), then dissolve it in Et2O, shake this with aqueous 5N NaOH, M H2SO4, saturated aqueous NaCl, dry (MgSO4) and distil it using an efficient column at atmospheric pressure. The 3,5-dinitrobenzoate has m 70-70.5o (from 95% EtOH). [Huang & Wang Acta Chem Sin 23 291 1957, cf. Chem Abstr 52 19911 1958, Speier et al. J Am Chem Soc 81 1844 1959 and Speier et al. J Am Chem Soc 70 1117 1948, Beilstein 4 III 1844, 4 IV 2876.]

1-TRIMETHYLSILYLMETHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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1-TRIMETHYLSILYLMETHANOL Suppliers

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View Lastest Price from 1-TRIMETHYLSILYLMETHANOL manufacturers

Hebei Mujin Biotechnology Co.,Ltd

Product: 1-TRIMETHYLSILYLMETHANOL 3219-63-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-08-09

Hebei Junhua Import and Export Co., LTD

Product: 1-TRIMETHYLSILYLMETHANOL 3219-63-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000
Release date: 2025-02-24

Career Henan Chemical Co

Product: 1-TRIMETHYLSILYLMETHANOL 3219-63-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: KG/T
Release date: 2019-12-17

3219-63-4, 1-TRIMETHYLSILYLMETHANOLRelated Search:

3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE TRIMETHYLSILYL DIETHYLPHOSPHONOACETATE (TRIMETHYLSILYL)CYCLOPENTADIENE, MIXTURE OF ISOMERS TRIMETHYLSILYL PROPIONATE TRIMETHYLSILYL TRIFLUOROACETATE 1-TRIMETHYLSILYLMETHANOL (TRIMETHYLSILYL)METHYL TRIFLUOROMETHANESULFONATE 1-(TRIMETHYLSILYL)ETHANOL, 98 (METHOXYMETHYL)TRIMETHYLSILANE (1-ETHOXYVINYL)-TRIMETHYLSILANE ACRYLOXYMETHYLTRIMETHYLSILANE (PHENYLDIMETHYLSILYL)METHYL METHACRYLATE (1-HYDROXYALLYL)TRIMETHYLSILANE 1-TRIETHYLSILYL-4-(TRIETHLYLSILYLOXY)-1-BUTYNE METHACRYLOXYMETHYLTRIMETHYLSILANE (2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine (1-METHOXYVINYL)TRIMETHYLSILANE TRIMETHYLSILYLMETHYL ACETATE

(hydroxymethyl)trimethyl-silan

(trimethylsilyl)-methano

Methanol, (trimethylsilyl)-

Silane, (hydroxymethyl)trimethyl-

TRIMETHYLHYDROXYMETHYLSILANE

(TRIMETHYLSILYL)METHANOL

1-TRIMETHYLSILYLMETHANOL

(HYDROXYMETHYL)TRIMETHYLSILANE

1-TRIMETHYLSILYLMETHANOL, 98+%

(Trimethylsilyl)methanol,(Hydroxymethyl)trimethylsilane

NSC 96777

Methanol,1-(trimethylsilyl)-

rimethylsilylmethanol

DK264

3219-63-4

C4H12OSi

CH33SiCH2OH

Alcohols

Building Blocks

C2 to C6

Organic Building Blocks

Oxygen Compounds

Silicon Compounds (for Synthesis)

Si (Classes of Silicon Compounds)

Si-(C)4 Compounds

Si (Classes of Silicon Compounds)

Si-(C)4 Compounds

Silicon Compounds (for Synthesis)

Synthetic Organic Chemistry