ChemicalBook > CAS DataBase List > (4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER

(4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER

Product Name
(4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER
CAS No.
494769-34-5
Chemical Name
(4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER
Synonyms
N-Boc-2-amino-4-formylthiazole;2-(Boc-amino)thiazole-4-carboxaldehyde;TERT-BUTYL 4-FORMYLTHIAZOL-2-YLCARBAMATE;tert-butyl N-(4-formylthiazol-2-yl)carbamate;tert-butyl N-(4-formyl-1,3-thiazol-2-yl)carbamate;(4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER;(4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER, 95+%;Carbamic acid, N-(4-formyl-2-thiazolyl)-, 1,1-dimethylethyl ester
CBNumber
CB7295933
Molecular Formula
C9H12N2O3S
Formula Weight
228.27
MOL File
494769-34-5.mol
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(4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER Property

Density 
1.320±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
4.89±0.70(Predicted)
Appearance
White to yellow Solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
F701455
Product name
(4-Formylthiazol-2-yl)carbamicAcidTert-butylEster
Packaging
250mg
Price
$85
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB154122
Product name
N-Boc-2-Amino-4-formylthiazole
Packaging
500mg
Price
$90
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB154122
Product name
N-Boc-2-Amino-4-formylthiazole
Packaging
1g
Price
$153
Updated
2021/12/16
AK Scientific
Product number
W6505
Product name
N-Boc-2-Amino-4-formylthiazole
Packaging
1g
Price
$192
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB154122
Product name
N-Boc-2-Amino-4-formylthiazole
Packaging
2g
Price
$266
Updated
2021/12/16
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(4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER Chemical Properties,Usage,Production

Synthesis

494769-44-7

494769-34-5

Step 3: tert-butyl (4-hydroxymethylthiazol-2-yl)carbamate (1.62 g, 6.95 mmol) was dissolved in 30 mL of dichloromethane. Manganese dioxide (3.65 g, 41.7 mmol) was added to this solution and the reaction mixture was stirred under reflux conditions for 2 hours. Upon completion of the reaction, the suspension was filtered through a diatomaceous earth Speed Plus pad and the filter cake was washed with dichloromethane. The filtrate was concentrated to afford the target product (4-formylthiazol-2-yl)carbamic acid tert-butyl ester as a light yellow solid (1.25 g, 78% yield). Mass spectrometry result: m/z = 229.2 ([M+H]+).

References

[1] Patent: US2007/78155, 2007, A1. Location in patent: Page/Page column 32
[2] Patent: US2006/154973, 2006, A1. Location in patent: Page/Page column 38
[3] Patent: WO2013/190508, 2013, A2. Location in patent: Page/Page column 55-56
[4] Patent: US2013/345199, 2013, A1. Location in patent: Paragraph 0579
[5] Patent: WO2016/44770, 2016, A1. Location in patent: Page/Page column 737

(4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER manufacturers

Career Henan Chemical Co
Product
(4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER 494769-34-5
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 652
Release date
2019-09-01

494769-34-5, (4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTERRelated Search:


  • TERT-BUTYL 4-FORMYLTHIAZOL-2-YLCARBAMATE
  • (4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER
  • N-Boc-2-amino-4-formylthiazole
  • (4-FORMYLTHIAZOL-2-YL)CARBAMIC ACID TERT-BUTYL ESTER, 95+%
  • 2-(Boc-amino)thiazole-4-carboxaldehyde
  • Carbamic acid, N-(4-formyl-2-thiazolyl)-, 1,1-dimethylethyl ester
  • tert-butyl N-(4-formylthiazol-2-yl)carbamate
  • tert-butyl N-(4-formyl-1,3-thiazol-2-yl)carbamate
  • 494769-34-5