4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

ChemicalBook > CAS DataBase List > 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

Product Name: 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
CAS No.: 160552-54-5
Chemical Name: 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
Synonyms: GI138870X;GI 138870X;GI-138870X;Lamivudine EP IMP H;Lamivudine EP Impurity G;Lamivudine sulfoxide, (R)-;Lamivudine Impurity (R-sulphoxide);Lamivudine EP Impurity H / R Sulfoxide;Lamivudine Impurity 8(Lamivudine EP Impurity H);Lamivudine EP Impurity H (Lamivudine (3R)-Sulfoxide)
CBNumber: CB73051758
Molecular Formula: C8H11N3O4S
Formula Weight: 245.26
MOL File: 160552-54-5.mol

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4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Property

Boiling point:: 601.7±65.0 °C(Predicted)
Density: 1.93±0.1 g/cm3(Predicted)
solubility: DMSO (Slightly, Heated), Water (Slightly, Heated, Sonicated)
pka: 13.46±0.10(Predicted)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: L172475
Product name: Lamivudine(R)-Sulfoxide
Packaging: 10mg
Price: $180
Updated: 2021/12/16

TRC

Product number: L172475
Product name: Lamivudine(R)-Sulfoxide
Packaging: 100mg
Price: $1390
Updated: 2021/12/16

AvaChem

Product number: 3822
Product name: 4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-on
Packaging: 5mg
Price: $175
Updated: 2021/12/16

AvaChem

Product number: 3822
Product name: 4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-on
Packaging: 10mg
Price: $275
Updated: 2021/12/16

AvaChem

Product number: 3822
Product name: 4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-on
Packaging: 25mg
Price: $575
Updated: 2021/12/16

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4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Chemical Properties,Usage,Production

Uses

Lamivudine (R)-Sulfoxide (Lamivudine EP Impurity H) is a metabolite of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.

4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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160552-54-5, 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-oneRelated Search:

5'-Epi-LaMivudine Lamivudine Impurity 1 (2R-cis)-5-(4-aMino-2-oxo-1(2H)-pyriMidinyl)-1,3-oxathiolane-2-carboxylic Acid Uracil ent-LaMivudine Lamivudine EP Impurity B TROXACITABINE Cytosine lamivudine sulfoxide Salicylic acid Lamivudine Aids004768 Lamivudine EP Impurity A

4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one-S-oxide

Lamivudine EP Impurity G

Lamivudine Impurity 8(Lamivudine EP Impurity H)

2(1H)-Pyrimidinone,4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]- (9CI)

2(1H)-Pyrimidinone, 4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-

4-Amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

Lamivudine EP Impurity H / R Sulfoxide

Lamivudine EP Impurity H (Lamivudine (3R)-Sulfoxide)

Lamivudine Impurit Ⅴ:4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

Lamivudine Impurity Ⅴ 4-amino-1-[(2R,3R,5S)-2-(hydro xymethyl)-1,3-oxathiolan-5-yl] pyrimidin-2(1H)-one-S-oxide

GI 138870X

GI138870X

GI-138870X

Lamivudine sulfoxide, (R)-

Lamivudine Impurity (R-sulphoxide)

Lamivudine EP IMP H

160552-54-5

60552-55-6

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