Ixazomib Impurity 1

Product Name: Ixazomib Impurity 1
CAS No.: 1201903-02-7
Chemical Name: Ixazomib Impurity 1
Synonyms: Ixazomib Impurity 1;Ixazomib Impurity R;Ixazomib Impurity N1;2,5-Dichloro-N-[2-({(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]dec-4-yl]butyl}amino)-2-oxoethyl]benzamide;2,5-Dichloro-N-[2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxoethyl]-benzamide;2,5-dichloro-N-(2-(((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-2-oxoethyl)benzamide;Benzamide, 2,5-dichloro-N-[2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxoethyl]-;2,5-dichloro-N-(2-(((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-2-oxoethyl)benzamide/ Ixazomib Impurity 1
CBNumber: CB73054683
Molecular Formula: C24H33BCl2N2O4
Formula Weight: 495.25
MOL File: 1201903-02-7.mol

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Ixazomib Impurity 1 Property

Boiling point:: 602.0±55.0 °C(Predicted)
Density: 1.25±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Dichloromethane; Chloroform; Methanol; Ethyl Acetate; DMSO;
form: Solid
pka: 12.10±0.46(Predicted)
color: White

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Hazard and Precautionary Statements (GHS)

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Ixazomib Impurity 1 Chemical Properties,Usage,Production

Uses

2,5-Dichloro-N-[2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxoethyl]-benzamide is an intermediate used in the synthesis of Ixazomib (I942000), which is a proteasome inhibitor that acts by preventing cell growth in solid tumours. It is an anticancer agent that is used to treat patients with multiple myeloma and is potentially neurotoxic.

Ixazomib Impurity 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Ixazomib Impurity 1 Suppliers

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1201903-02-7, Ixazomib Impurity 1Related Search:

MLN9708 (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Ixazomib citrate (USAN) Acetamide, 2-amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-

Ixazomib Impurity 1

2,5-dichloro-N-(2-(((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-2-oxoethyl)benzamide

2,5-Dichloro-N-[2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxoethyl]-benzamide

Benzamide, 2,5-dichloro-N-[2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxoethyl]-

Ixazomib Impurity N1

Ixazomib Impurity R

2,5-dichloro-N-(2-(((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-2-oxoethyl)benzamide/ Ixazomib Impurity 1

2,5-Dichloro-N-[2-({(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]dec-4-yl]butyl}amino)-2-oxoethyl]benzamide

1201903-02-7

C24H33BCl2N2O4