ChemicalBook > CAS DataBase List > (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
- Product Name
- (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
- CAS No.
- 1072833-77-2
- Chemical Name
- (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
- Synonyms
- IxazoMib;MLN2238;Ixazomib-d7;CS-1976;MLN2238(Ixazomib);MLN2238(iaxzomib);ixazomib(MLN2238);Ixazomib (MLN-9708);Ixazomib (10mM in DMSO);MLN2238;MLN 2238;MLN-2238
- CBNumber
- CB62521080
- Molecular Formula
- C14H19BCl2N2O4
- Formula Weight
- 361.03
- MOL File
- 1072833-77-2.mol
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(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Property
- Melting point:
- >142°C (subl.)
- Density
- 1.306
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Sparingly), Methanol (Slightly)
- pka
- 9.67±0.43(Predicted)
- form
- Solid
- color
- White to Pale Yellow
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
- Precautionary statements
-
P201Obtain special instructions before use.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P263Avoid contact during pregnancy/while nursing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P308+P313IF exposed or concerned: Get medical advice/attention.
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 18385
- Product name
- MLN2238
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18385
- Product name
- MLN2238
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $193
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18385
- Product name
- MLN2238
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $341
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18385
- Product name
- MLN2238
- Purity
- ≥95%
- Packaging
- 50mg
- Price
- $1169
- Updated
- 2024/03/01
TRC
- Product number
- I942000
- Product name
- Ixazomib
- Packaging
- 100mg
- Price
- $700
- Updated
- 2021/12/16
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(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Chemical Properties,Usage,Production
Uses
Ixazomib is a proteasome inhibitor that acts by preventing cell growth in solid tumours. It is an anticancer agent that is used to treat patients with multiple myeloma and is potentially neurotoxic.
Definition
ChEBI: A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixa omib citrate, it is used in combination therapy for treatment of multiple myeloma.
target
chymotrypsin-like proteolytic (β5) site of the 20S proteasome
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Suppliers
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View Lastest Price from (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid manufacturers
Henan Fengda Chemical Co., Ltd
- Product
- (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid 1072833-77-2
- Price
- US $6.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-28
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid 1072833-77-2
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 98%-102%
- Supply Ability
- 100G
- Release date
- 2021-06-29
Career Henan Chemical Co
- Product
- (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid 1072833-77-2
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24
1072833-77-2, (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acidRelated Search:
Ixazomib citrate (USAN)
Acetamide, 2-amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-
Ixazomib Impurity 1
CUDC-101
Brivanib alaninate
AC480 (BMS-599626)
1H-indazole-7-carboxylic acid
tert-butyl (S)-3-(4-bromophenyl)piperidine-1-carboxylate
Niraparib
(S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
Piperidine, 3-(4-bromophenyl)-
(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate
4-piperidin-3-ylaniline
CHEMBRDG-BB 7959525
Methyl 3-formyl-2-nitrobenzoate
Bortezomib
MLN9708
MK-2206 2HCl