ChemicalBook > CAS DataBase List > (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid

Product Name
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
CAS No.
1072833-77-2
Chemical Name
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
Synonyms
IxazoMib;MLN2238;Ixazomib-d7;CS-1976;MLN2238(Ixazomib);MLN2238(iaxzomib);ixazomib(MLN2238);Ixazomib (MLN-9708);Ixazomib (10mM in DMSO);MLN2238;MLN 2238;MLN-2238
CBNumber
CB62521080
Molecular Formula
C14H19BCl2N2O4
Formula Weight
361.03
MOL File
1072833-77-2.mol
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(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Property

Melting point:
>142°C (subl.)
Density 
1.306
storage temp. 
-20°C Freezer
solubility 
DMSO (Sparingly), Methanol (Slightly)
pka
9.67±0.43(Predicted)
form 
Solid
color 
White to Pale Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

H362May cause harm to breast-fed children

Precautionary statements

P201Obtain special instructions before use.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
18385
Product name
MLN2238
Purity
≥95%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
18385
Product name
MLN2238
Purity
≥95%
Packaging
5mg
Price
$193
Updated
2024/03/01
Cayman Chemical
Product number
18385
Product name
MLN2238
Purity
≥95%
Packaging
10mg
Price
$341
Updated
2024/03/01
Cayman Chemical
Product number
18385
Product name
MLN2238
Purity
≥95%
Packaging
50mg
Price
$1169
Updated
2024/03/01
TRC
Product number
I942000
Product name
Ixazomib
Packaging
100mg
Price
$700
Updated
2021/12/16
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(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Chemical Properties,Usage,Production

Uses

Ixazomib is a proteasome inhibitor that acts by preventing cell growth in solid tumours. It is an anticancer agent that is used to treat patients with multiple myeloma and is potentially neurotoxic.

Definition

ChEBI: A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixa omib citrate, it is used in combination therapy for treatment of multiple myeloma.

target

chymotrypsin-like proteolytic (β5) site of the 20S proteasome

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid 1072833-77-2
Price
US $6.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28
WUHAN FORTUNA CHEMICAL CO., LTD
Product
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid 1072833-77-2
Price
US $0.00/g
Min. Order
1g
Purity
98%-102%
Supply Ability
100G
Release date
2021-06-29
Career Henan Chemical Co
Product
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid 1072833-77-2
Price
US $2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-24

1072833-77-2, (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acidRelated Search:

Ixazomib citrate (USAN) Acetamide, 2-amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]- Ixazomib Impurity 1 CUDC-101 Brivanib alaninate AC480 (BMS-599626) 1H-indazole-7-carboxylic acid tert-butyl (S)-3-(4-bromophenyl)piperidine-1-carboxylate Niraparib (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate Piperidine, 3-(4-bromophenyl)- (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate 4-piperidin-3-ylaniline CHEMBRDG-BB 7959525 Methyl 3-formyl-2-nitrobenzoate Bortezomib MLN9708 MK-2206 2HCl

  • MLN2238
  • IxazoMib
  • (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
  • IXAZOMIB;MLN 2238;MLN-2238
  • CS-1976
  • 1-(2-(2,5-dichlorobenzamido)acetamido)- 3-methylbutylboronic acid
  • B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid
  • ixazomib(MLN2238)
  • B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid Ixazomib (MLN2238)
  • MLN2238(iaxzomib)
  • MLN2238(Ixazomib)
  • MLN2238;MLN 2238;MLN-2238
  • Ixazomib (MLN-9708)
  • Ixazomib-d7
  • Ixazomib, 98%, a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM)
  • (1R)-1-{2-[(2,5-dichlorophenyl)formamido]acetamido}-3-methylbutyl]boronic acid
  • Boronic acid, B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-
  • (R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbuyl)boronic acid
  • Ixazomib (10mM in DMSO)
  • Ixazomib-13C2,15NQ: What is Ixazomib-13C2,15N Q: What is the CAS Number of Ixazomib-13C2,15N
  • 1072833-77-2
  • C14H19BCl2N2O4
  • Inhibitors
  • Inhibitor
  • apis