ChemicalBook > CAS DataBase List > Fluorescein-PEG2-Azide

Fluorescein-PEG2-Azide

Product Name
Fluorescein-PEG2-Azide
CAS No.
1146195-72-3
Chemical Name
Fluorescein-PEG2-Azide
Synonyms
FITC-PEG2-N3;5-FITC-PEG2-azide;Fluorescein-PEG2-N3;Fluorescein-PEG8-Azide;Fluorescein-PEG2-Azide;Fluorescein-thiourea-PEG2-azide
CBNumber
CB73062495
Molecular Formula
C27H25N5O7S
Formula Weight
563.59
MOL File
1146195-72-3.mol
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Fluorescein-PEG2-Azide Property

solubility 
Soluble in DMSO, DMF, DCM
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-20956
Product name
Fluorescein-PEG2-azide
Purity
96%
Packaging
1mg
Price
$180
Updated
2021/12/16
AK Scientific
Product number
AMTGC479
Product name
Fluorescein-PEG2-azide
Packaging
25mg
Price
$195
Updated
2021/12/16
BroadPharm
Product number
BP-20956
Product name
Fluorescein-PEG2-azide
Purity
96%
Packaging
5mg
Price
$320
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
FRL0001927
Product name
FLUORESCEIN-PEG2-AZIDE
Purity
95.00%
Packaging
5MG
Price
$496.64
Updated
2021/12/16
AK Scientific
Product number
AMTGC479
Product name
Fluorescein-PEG2-azide
Packaging
100mg
Price
$682
Updated
2021/12/16
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Fluorescein-PEG2-Azide Chemical Properties,Usage,Production

Description

Fluorescein-PEG2-azide is a green emitting fluorescent dye derivitative with excitation/emmission maximum 494/517 nm containing an azide group, which enables Click Chemistry. The hydophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding.

Uses

Fluorescein-thiourea-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Fluorescein-thiourea-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Fluorescein-PEG2-Azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Fluorescein-PEG2-Azide Suppliers

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View Lastest Price from Fluorescein-PEG2-Azide manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
5-FITC-PEG2-azide 1146195-72-3
Price
US $0.00/mg
Min. Order
10mg
Purity
>99.00%
Supply Ability
10mg
Release date
2024-03-28