Mal-amido-PEG2-TFP ester

Product Name: Mal-amido-PEG2-TFP ester
CAS No.: 1431291-44-9
Chemical Name: Mal-amido-PEG2-TFP ester
Synonyms: Mal-NH-PEG2-TFP;MAL-dPEG2-TFP ester;MAL-dPEG??-TFP ester;Mal-amido-PEG2-TFP ester;Propanoic acid, 3-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]-, 2,3,5,6-tetrafluorophenyl ester
CBNumber: CB73062521
Molecular Formula: C20H20F4N2O7
Formula Weight: 476.38
MOL File: 1431291-44-9.mol

More

Less

Mal-amido-PEG2-TFP ester Property

solubility: Soluble in DMSO, DCM, DMF
form: Solid

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: M111058
Product name: Mal-amido-PEG2-TFPester
Packaging: 50mg
Price: $110
Updated: 2021/12/16

BroadPharm

Product number: BP-22739
Product name: Mal-amido-PEG2-TFPester
Purity: 95%
Packaging: 250mg
Price: $180
Updated: 2021/12/16

BroadPharm

Product number: BP-22739
Product name: Mal-amido-PEG2-TFPester
Purity: 95%
Packaging: 1g
Price: $350
Updated: 2021/12/16

dPEG

Product number: 10553
Product name: MAL-dPEG®₁₂-TFPester
Packaging: 1000mg
Price: $750
Updated: 2021/12/16

BroadPharm

Product number: BP-22739
Product name: Mal-amido-PEG2-TFPester
Purity: 95%
Packaging: 5G
Price: $1330
Updated: 2021/12/16

More

Less

Mal-amido-PEG2-TFP ester Chemical Properties,Usage,Production

Description

Mal-amido-PEG2-TFP ester is PEG linker containing a maleimide and TFP ester end group. Maleimide groups are reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chains increase the water solubility of a compound in aqueous media. Longer PEG chains have improved water solubility relative to shorter PEG chains.

Uses

Mal-amido-PEG2-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Mal-amido-PEG2-TFP ester Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Mal-amido-PEG2-TFP ester Suppliers

China 36 United Kingdom 1 United States 3 Global 40

Chengdu Pukang Biotechnology Co., Ltd

Tel: +86-028-82550498 +86-19102685862
Fax: 086-28-82550468
Email: sales@pu-kang.com
Country: China
ProdList: 489
Advantage: 58

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5874
Advantage: 58

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4838
Advantage: 58

Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
Fax: 0411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 1951
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-66110311 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15526
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32222
Advantage: 58

Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19908
Advantage: 58

Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 029-86217788 13892832556
Email: 2440688701@qq.com
Country: China
ProdList: 1986
Advantage: 58

More

Less

View Lastest Price from Mal-amido-PEG2-TFP ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Mal-amido-PEG2-TFP ester 1431291-44-9
Price: US $0.00/mg
Min. Order: 50mg
Purity: >98.00%
Supply Ability: 50mg
Release date: 2024-05-10

1431291-44-9, Mal-amido-PEG2-TFP esterRelated Search:

Mal-amido-PEG4-TFP ester Mal-amido-PEG12-TFP ester Mal-amido-PEG8-TFP ester

Mal-amido-PEG2-TFP ester

Mal-NH-PEG2-TFP

Propanoic acid, 3-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]-, 2,3,5,6-tetrafluorophenyl ester

MAL-dPEG??-TFP ester

MAL-dPEG2-TFP ester

1431291-44-9

431291-44-9

C20H20F4N2O7

peg