ChemicalBook > CAS DataBase List > 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride
5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride
Uses- Product Name
- 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride
- CAS No.
- 1289646-93-0
- Chemical Name
- 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride
- Synonyms
- 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid hydrochloride;6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride;Lifitegrast Impurity 5;lifitegrast-impurity IV-3;Lifitegrast Intermediate 2;6-ISOQUINOLINECARBOXYLIC ACID,5,7-DICHLORO-1,2,3,4-TETRAHYDR...;5,7-Dichloro-1,2,3,4-tetrahydro-6-isoquinolinecarboxylic acid hydrochloride (1:1);6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride (1;6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride (1:1)
- CBNumber
- CB73137955
- Molecular Formula
- C10H10Cl3NO2
- Formula Weight
- 282.55
- MOL File
- 1289646-93-0.mol
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5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride Property
- InChI
- InChI=1S/C10H9Cl2NO2.ClH/c11-7-3-5-4-13-2-1-6(5)9(12)8(7)10(14)15;/h3,13H,1-2,4H2,(H,14,15);1H
- InChIKey
- CGXSFPJGZFRGNL-UHFFFAOYSA-N
- SMILES
- ClC1C(=C(Cl)C=C2CNCCC=12)C(=O)O.Cl
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
AK Scientific
- Product number
- 8781EL
- Product name
- 5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylicacidhydrochloride
- Packaging
- 1g
- Price
- $532
- Updated
- 2021/12/16
AK Scientific
- Product number
- 8781EL
- Product name
- 5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylicacidhydrochloride
- Packaging
- 10g
- Price
- $2085
- Updated
- 2021/12/16
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5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride Chemical Properties,Usage,Production
Uses
6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride (1:1) is a quinoline derivative used in pharmaceutical synthesis.
General Description
5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride, also known as Lifitegrast Impurity 5, is an impurity of Lifitegrast. Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process.
5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride Suppliers
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View Lastest Price from 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride manufacturers
Guangzhou Tosun Pharmaceutical Limited
- Product
- Lifitegrast Impurity 5 1289646-93-0
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 98.49%
- Supply Ability
- 10g/month
- Release date
- 2023-05-10
Career Henan Chemical Co
- Product
- Lifitegrast Intermediate 2 1289646-93-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-25
1289646-93-0, 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid HydrochlorideRelated Search:
Lifitegrast Impurity 6
Lifitegrast Impurity 3
Lifitegrast Impurity 9 HCl
Lifitegrast Impurity 8
2(1H)-Isoquinolinecarboxylic acid, 5,7-dichloro-3,4-dihydro-6-[[[(1S)-1-[[3-(methylsulfonyl)phenyl]methyl]-2-oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]-, 1,1-dimethylethyl ester
lifitegrast
benzyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate
(R)-Benzyl 2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride
Ethyl benzofuran-6-carboxylate
L-Phenylalanine, N-[(5,7-dichloro-1,2,3,4-tetrahydro-6-isoquinolinyl)carbonyl]-3-(methylsulfonyl)-, phenylmethyl ester, hydrochloride (1:1)
5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride