5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride

Uses

Product Name: 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride
CAS No.: 1289646-93-0
Chemical Name: 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride
Synonyms: 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid hydrochloride;6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride;Lifitegrast Impurity 5;lifitegrast-impurity IV-3;Lifitegrast Intermediate 2;6-ISOQUINOLINECARBOXYLIC ACID,5,7-DICHLORO-1,2,3,4-TETRAHYDR...;5,7-Dichloro-1,2,3,4-tetrahydro-6-isoquinolinecarboxylic acid hydrochloride (1:1);6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride (1;6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride (1:1)
CBNumber: CB73137955
Molecular Formula: C10H10Cl3NO2
Formula Weight: 282.55
MOL File: 1289646-93-0.mol

More

Less

5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride Property

InChI: InChI=1S/C10H9Cl2NO2.ClH/c11-7-3-5-4-13-2-1-6(5)9(12)8(7)10(14)15;/h3,13H,1-2,4H2,(H,14,15);1H
InChIKey: CGXSFPJGZFRGNL-UHFFFAOYSA-N
SMILES: ClC1C(=C(Cl)C=C2CNCCC=12)C(=O)O.Cl

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

AK Scientific

Product number: 8781EL
Product name: 5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylicacidhydrochloride
Packaging: 1g
Price: $532
Updated: 2021/12/16

AK Scientific

Product number: 8781EL
Product name: 5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylicacidhydrochloride
Packaging: 10g
Price: $2085
Updated: 2021/12/16

More

Less

5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride Chemical Properties,Usage,Production

Uses

6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride (1:1) is a quinoline derivative used in pharmaceutical synthesis.

General Description

5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride, also known as Lifitegrast Impurity 5, is an impurity of Lifitegrast. Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process.

5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride Suppliers

China 93 India 3 United States 3 Global 99

SynZeal Research Pvt Ltd

Tel: --
Fax: --
Email: standards@synzeal.com
Country: India
ProdList: 6514
Advantage: 58

More

Less

View Lastest Price from 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride manufacturers

Guangzhou Tosun Pharmaceutical Limited

Product: Lifitegrast Impurity 5 1289646-93-0
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 98.49%
Supply Ability: 10g/month
Release date: 2023-05-10

Career Henan Chemical Co

Product: Lifitegrast Intermediate 2 1289646-93-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-25

1289646-93-0, 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid HydrochlorideRelated Search:

Lifitegrast Impurity 6 Lifitegrast Impurity 3 Lifitegrast Impurity 9 HCl Lifitegrast Impurity 8 2(1H)-Isoquinolinecarboxylic acid, 5,7-dichloro-3,4-dihydro-6-[[[(1S)-1-[[3-(methylsulfonyl)phenyl]methyl]-2-oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]-, 1,1-dimethylethyl ester lifitegrast benzyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate (R)-Benzyl 2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride Ethyl benzofuran-6-carboxylate L-Phenylalanine, N-[(5,7-dichloro-1,2,3,4-tetrahydro-6-isoquinolinyl)carbonyl]-3-(methylsulfonyl)-, phenylmethyl ester, hydrochloride (1:1) 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride

6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride (1:1)

6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride

5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid hydrochloride

6-Isoquinolinecarboxylic acid, 5,7-dichloro-1,2,3,4-tetrahydro-, hydrochloride (1

Lifitegrast Intermediate 2

Lifitegrast Impurity 5

5,7-Dichloro-1,2,3,4-tetrahydro-6-isoquinolinecarboxylic acid hydrochloride (1:1)

lifitegrast-impurity IV-3

6-ISOQUINOLINECARBOXYLIC ACID,5,7-DICHLORO-1,2,3,4-TETRAHYDR...

1289646-93-0