Ilexhainanoside D
- Product Name
- Ilexhainanoside D
- CAS No.
- 1137648-52-2
- Chemical Name
- Ilexhainanoside D
- Synonyms
- Ilexhainanoside D;Olean-12-ene-23,28-dioic acid, 3,19-dihydroxy-, 28-β-D-glucopyranosyl ester, (3β,4β,19α)-
- CBNumber
- CB73158549
- Molecular Formula
- C36H56O11
- Formula Weight
- 664.83
- MOL File
- 1137648-52-2.mol
Ilexhainanoside D Property
- Boiling point:
- 788.1±60.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- pka
- 4.47±0.70(Predicted)
N-Bromosuccinimide Price
- Product number
- 4251
- Product name
- Ilexhainanoside D
- Packaging
- 1mg
- Price
- $119
- Updated
- 2021/12/16
- Product number
- CFN90989
- Product name
- IlexhainanosideD
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $208
- Updated
- 2021/12/16
- Product number
- 4251
- Product name
- Ilexhainanoside D
- Packaging
- 5mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- 4251
- Product name
- Ilexhainanoside D
- Packaging
- 10mg
- Price
- $490
- Updated
- 2021/12/16
- Product number
- 4251
- Product name
- Ilexhainanoside D
- Packaging
- 20mg
- Price
- $690
- Updated
- 2021/12/16
Ilexhainanoside D Chemical Properties,Usage,Production
Uses
Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect[1].
in vivo
The combination of Ilexhainanoside D and Ilexsaponin A (60, 120 or 240?mg/kg; for 8 weeks) treatment significantly reduces the severity of non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet in a dose-dependent manner. The combination of Ilexhainanoside D and Ilexsaponin A treatment decreases the ratio of Firmicutes/Bacteroidetes, reduces the relative abundance of Desulfovibrio and increases the relative abundance of Akkermansia. The intestinal barrier is improved as evidenced by the upregulation of the expression of zonula occludens-1 (ZO-1) and occludin in the ileum. The combination of Ilexhainanoside D and Ilexsaponin A treatment reduces the entry of LPS into the circulation and decreases the hepatic gene expression levels of proinflammatory cytokines[1].
References
[1] Zhao W, et al. The combination of Ilexhainanoside D and ilexsaponin A1 reduces liver inflammation and improves intestinal barrier function in mice with high-fat diet-induced non-alcoholic fatty liver disease. Phytomedicine. 2019 Jul 26;63:153039. DOI:10.1016/j.phymed.2019.153039
Ilexhainanoside D Preparation Products And Raw materials
Raw materials
Preparation Products
Ilexhainanoside D Suppliers
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- Country
- United States
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View Lastest Price from Ilexhainanoside D manufacturers
- Product
- Ilexhainanoside D 1137648-52-2
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-26
- Product
- Ilexhainanoside D 1137648-52-2
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ＞98%
- Supply Ability
- 20 tons
- Release date
- 2020-02-10
- Product
- Ilexhainanoside D 1137648-52-2
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ＞98%
- Supply Ability
- 20 tons
- Release date
- 2020-02-10