SGC2085

Product Name: SGC2085
CAS No.: 1821908-48-8
Chemical Name: SGC2085
Synonyms: CS-2688;CS-2529;SGC-2085; SGC 2085;SGC2085, 10 mM in DMSO;(S)-2-Amino-N-(4-(3,5-dimethylphenoxy)-3-methylbenzyl)propanamide;SGC2085,SGC 2085,Inhibitor,inhibit,SGC-2085,Histone Methyltransferase;(2S)-2-Amino-N-[[4-(3,5-dimethylphenoxy)-3-methylphenyl]methyl]Propanamide;Propanamide, 2-amino-N-[[4-(3,5-dimethylphenoxy)-3-methylphenyl]methyl]-, (2S)-
CBNumber: CB73160081
Molecular Formula: C19H24N2O2
Formula Weight: 312.41
MOL File: 1821908-48-8.mol

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SGC2085 Property

Boiling point:: 498.3±45.0 °C(Predicted)
Density: 1.097±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO : ≥ 32 mg/mL (102.43 mM)
pka: 14.83±0.46(Predicted)
form: Solid
color: White to off-white
InChI: InChI=1S/C19H24N2O2/c1-12-7-13(2)9-17(8-12)23-18-6-5-16(10-14(18)3)11-21-19(22)15(4)20/h5-10,15H,11,20H2,1-4H3,(H,21,22)/t15-/m0/s1
InChIKey: GLFOFXKMALJTCZ-HNNXBMFYSA-N
SMILES: C(NCC1=CC=C(OC2=CC(C)=CC(C)=C2)C(C)=C1)(=O)[C@@H](N)C

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-6152
Product name: SGC2085
Purity: 99.87%
Packaging: 1mg
Price: $110
Updated: 2021/12/16

ChemScene

Product number: CS-6152
Product name: SGC2085
Purity: 99.87%
Packaging: 5mg
Price: $330
Updated: 2021/12/16

ChemScene

Product number: CS-6152
Product name: SGC2085
Purity: 99.87%
Packaging: 10mg
Price: $500
Updated: 2021/12/16

AK Scientific

Product number: 5127EG
Product name: (2S)-2-Amino-N-[[4-(3,5-dimethylphenoxy)-3-methylphenyl]methyl]propanamide
Packaging: 250mg
Price: $439
Updated: 2021/12/16

ChemScene

Product number: CS-6152
Product name: SGC2085
Purity: 99.87%
Packaging: 50mg
Price: $1500
Updated: 2021/12/16

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SGC2085 Chemical Properties,Usage,Production

Uses

SGC2085 is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with an IC50 of 50 nM. SGC2085 also selectively inhibits PRMT6 with an IC50 value of 5.2 μM, but not other PRMT proteins[1].

IC 50

PRMT4

References

[1] Ferreira de Freitas R, et al. Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening. J Med Chem. 2016 Jul 28;59(14):6838-47. DOI:10.1021/acs.jmedchem.6b00668

SGC2085 Preparation Products And Raw materials

Raw materials

Preparation Products

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SGC2085 Suppliers

China 55 India 1 United States 7 Global 63

Shanghai Dongyang Biotechnology Co., Ltd.

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1821908-48-8, SGC2085Related Search:

1-Piperazinecarboxylic acid, 4-[3-amino-6-(2-hydroxyphenyl)-4-pyridazinyl]-, 1,1-dimethylethyl ester SGC-GAK-1 SGC707 SGC0946

SGC-2085; SGC 2085

CS-2529

CS-2688

Propanamide, 2-amino-N-[[4-(3,5-dimethylphenoxy)-3-methylphenyl]methyl]-, (2S)-

(2S)-2-Amino-N-[[4-(3,5-dimethylphenoxy)-3-methylphenyl]methyl]Propanamide

SGC2085,SGC 2085,Inhibitor,inhibit,SGC-2085,Histone Methyltransferase

(S)-2-Amino-N-(4-(3,5-dimethylphenoxy)-3-methylbenzyl)propanamide

SGC2085, 10 mM in DMSO

1821908-48-8

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