DNP-PEG3-azide

Product Name: DNP-PEG3-azide
CAS No.: 951671-87-7
Chemical Name: DNP-PEG3-azide
Synonyms: N3-PEG3-DNP;DNP-PEG3-N3;DNP-PEG3-azide;Reaxys ID: 11170481;N-(2-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)ethyl)-2,4-dinitroaniline
CBNumber: CB73162944
Molecular Formula: C14H20N6O7
Formula Weight: 384.35
MOL File: 951671-87-7.mol

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DNP-PEG3-azide Property

storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23248
Product name: DNP-PEG3-azide
Purity: 98%
Packaging: 100mg
Price: $290
Updated: 2021/12/16

BroadPharm

Product number: BP-23248
Product name: DNP-PEG3-azide
Purity: 98%
Packaging: 250mg
Price: $480
Updated: 2021/12/16

BroadPharm

Product number: BP-23248
Product name: DNP-PEG3-azide
Purity: 98%
Packaging: 500mg
Price: $750
Updated: 2021/12/16

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DNP-PEG3-azide Chemical Properties,Usage,Production

Description

DNP-PEG3-azide is a PEG linker containing DNP and azide moieties. DNP is involved in biological applications such as participating in ion transport across membranes. The azide can react with alkynes, DBCO and BCN in copper-catalyzed Click Chemistry reactions. The hydrophilic PEG spacer increases the water solubility of the compound in aqueous media.

Uses

DNP-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DNP-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DNP-PEG3-azide Preparation Products And Raw materials

Raw materials

Preparation Products

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DNP-PEG3-azide Suppliers

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View Lastest Price from DNP-PEG3-azide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: DNP-PEG3-N3 951671-87-7
Price: US $0.00/mg
Min. Order: 500mg
Purity: >98.00%
Supply Ability: 500mg
Release date: 2024-03-25

951671-87-7, DNP-PEG3-azideRelated Search:

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DNP-PEG3-azide

Reaxys ID: 11170481

DNP-PEG3-N3

N3-PEG3-DNP

N-(2-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)ethyl)-2,4-dinitroaniline

951671-87-7

C14H20N6O7