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Fmoc-PEG12-NHS ester

Product Name
Fmoc-PEG12-NHS ester
CAS No.
2227246-92-4
Chemical Name
Fmoc-PEG12-NHS ester
Synonyms
Fmoc-NH-PEG12-NHS;Fmoc-PEG12-NHS ester;FmocNH-PEG12-NHS?ester;FmocNH-PEG12-CH2CH2COONHS;Inhibitor,Fmoc-PEG-12-NHS ester,FmocPEG12NHS ester,PROTAC Linkers,Fmoc PEG12 NHS ester,inhibit;2,5-Dioxopyrrolidin-1-yl 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oate;5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester;FmocNH-PEG12-CH2CH2COONHS/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester
CBNumber
CB73162964
Molecular Formula
C46H68N2O18
Formula Weight
937.03
MOL File
2227246-92-4.mol
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Fmoc-PEG12-NHS ester Property

solubility 
Soluble in DCM
form 
Viscous Liquid
color 
Colorless to light yellow
InChIKey
HQKUPHFWWTZASE-UHFFFAOYSA-N
SMILES
C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(=O)CCC1=O)=O
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Apolloscientific
Product number
BIPG1422
Product name
Fmoc-PEG12-NHS ester
Packaging
100mg
Price
$623
Updated
2021/12/16
BroadPharm
Product number
BP-22241
Product name
Fmoc-PEG12-NHSester
Purity
95%
Packaging
500mg
Price
$650
Updated
2021/12/16
BroadPharm
Product number
BP-22241
Product name
Fmoc-PEG12-NHSester
Purity
95%
Packaging
1g
Price
$860
Updated
2021/12/16
Activate Scientific
Product number
AS107822
Product name
FmocNH-PEG12-CH2CH2COONHS
Purity
97%
Packaging
1g
Price
$969
Updated
2021/12/16
BroadPharm
Product number
BP-22241
Product name
Fmoc-PEG12-NHSester
Purity
95%
Packaging
2g
Price
$1290
Updated
2021/12/16
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Fmoc-PEG12-NHS ester Chemical Properties,Usage,Production

Description

Fmoc-PEG12-NHS ester is a PEG linker containing an Fmoc-protected amine and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Fmoc-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Fmoc-PEG12-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-PEG12-NHS ester Suppliers

Changsha Morning Shine Co., Ltd.
Tel
18975870350 13397510867
Email
liyan@csmspharm.com
Country
China
ProdList
289
Advantage
58
Alabiochem Tech.Co., Ltd.
Tel
512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
970
Advantage
59
Chengdu Pukang Biotechnology Co., Ltd
Tel
+86-028-82550498 +86-19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
489
Advantage
58
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28803
Advantage
58
Adachibio Inc.
Tel
+8108027837258
Fax
0086-411-39042693
Email
sales@adachi-bio.com
Country
China
ProdList
992
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4838
Advantage
58
Alpha Biopharmaceuticals Co., Ltd
Tel
0411-39042497
Fax
0411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
1951
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32197
Advantage
58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel
029-86217788 13892832556
Email
2440688701@qq.com
Country
China
ProdList
1986
Advantage
58
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View Lastest Price from Fmoc-PEG12-NHS ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
FmocNH-PEG12-NHS ester 2227246-92-4
Price
US $0.00/g
Min. Order
1g
Purity
>99.00%
Supply Ability
1g
Release date
2024-03-25

2227246-92-4, Fmoc-PEG12-NHS esterRelated Search:


  • Fmoc-PEG12-NHS ester
  • FmocNH-PEG12-NHS?ester
  • FmocNH-PEG12-CH2CH2COONHS
  • 5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester
  • Fmoc-NH-PEG12-NHS
  • Inhibitor,Fmoc-PEG-12-NHS ester,FmocPEG12NHS ester,PROTAC Linkers,Fmoc PEG12 NHS ester,inhibit
  • FmocNH-PEG12-CH2CH2COONHS/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester
  • 2,5-Dioxopyrrolidin-1-yl 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oate
  • 2227246-92-4
  • C46H68N2O18