Fmoc-PEG12-NHS ester
- Product Name
- Fmoc-PEG12-NHS ester
- CAS No.
- 2227246-92-4
- Chemical Name
- Fmoc-PEG12-NHS ester
- Synonyms
- Fmoc-NH-PEG12-NHS;Fmoc-PEG12-NHS ester;FmocNH-PEG12-NHS?ester;FmocNH-PEG12-CH2CH2COONHS;Inhibitor,Fmoc-PEG-12-NHS ester,FmocPEG12NHS ester,PROTAC Linkers,Fmoc PEG12 NHS ester,inhibit;2,5-Dioxopyrrolidin-1-yl 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oate;5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester;FmocNH-PEG12-CH2CH2COONHS/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 41-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester
- CBNumber
- CB73162964
- Molecular Formula
- C46H68N2O18
- Formula Weight
- 937.03
- MOL File
- 2227246-92-4.mol
Fmoc-PEG12-NHS ester Property
- storage temp.
- Storage temp. -20°C
- solubility
- Soluble in DCM
- form
- Viscous Liquid
- color
- Colorless to light yellow
- InChIKey
- HQKUPHFWWTZASE-UHFFFAOYSA-N
- SMILES
- C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(=O)CCC1=O)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BIPG1422
- Product name
- Fmoc-PEG12-NHS ester
- Packaging
- 100mg
- Price
- $623
- Updated
- 2021/12/16
- Product number
- BP-22241
- Product name
- Fmoc-PEG12-NHSester
- Purity
- 95%
- Packaging
- 500mg
- Price
- $650
- Updated
- 2021/12/16
- Product number
- BP-22241
- Product name
- Fmoc-PEG12-NHSester
- Purity
- 95%
- Packaging
- 1g
- Price
- $860
- Updated
- 2021/12/16
- Product number
- AS107822
- Product name
- FmocNH-PEG12-CH2CH2COONHS
- Purity
- 97%
- Packaging
- 1g
- Price
- $969
- Updated
- 2021/12/16
- Product number
- BP-22241
- Product name
- Fmoc-PEG12-NHSester
- Purity
- 95%
- Packaging
- 2g
- Price
- $1290
- Updated
- 2021/12/16
Fmoc-PEG12-NHS ester Chemical Properties,Usage,Production
Description
Fmoc-PEG12-NHS ester is a PEG linker containing an Fmoc-protected amine and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Uses
Fmoc-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fmoc-PEG12-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-PEG12-NHS ester Suppliers
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View Lastest Price from Fmoc-PEG12-NHS ester manufacturers
- Product
- FmocNH-PEG12-NHS 2227246-92-4
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-06
- Product
- FmocNH-PEG12-NHS ester 2227246-92-4
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >99.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25