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BETULINIC ACID METHYL ESTER

Product Name
BETULINIC ACID METHYL ESTER
CAS No.
2259-06-5
Chemical Name
BETULINIC ACID METHYL ESTER
Synonyms
Methylbetulinate;betulinate, Methyl;BETULINIC ACID METHYL ESTER;BETULINIC ACID METHYL ESTER hplc;BETULINIC ACID METHYLESTER WITH HPLC;3B-HYDROXY-LUP-20(29)-EN-28-OIC ACID METHYL ESTER;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3)-;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3β)-;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3beta)-
CBNumber
CB7322703
Molecular Formula
C31H50O3
Formula Weight
470.73
MOL File
2259-06-5.mol
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BETULINIC ACID METHYL ESTER Property

Melting point:
222-223°C
Boiling point:
523.5±33.0 °C(Predicted)
Density 
1.036±0.06 g/cm3(Predicted)
pka
15.16±0.70(Predicted)
form 
A solid
LogP
9.400 (est)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
30066
Product name
Betulinic Acid methyl ester
Packaging
1mg
Price
$153
Updated
2024/03/01
Cayman Chemical
Product number
30066
Product name
Betulinic Acid methyl ester
Packaging
5mg
Price
$456
Updated
2024/03/01
TRC
Product number
B330253
Product name
BetulinicAcidMethylEster
Packaging
0.5mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB66104
Product name
Betulinic acid methyl ester
Packaging
25mg
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB66104
Product name
Betulinic acid methyl ester
Packaging
50mg
Price
$137.5
Updated
2021/12/16
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BETULINIC ACID METHYL ESTER Chemical Properties,Usage,Production

Description

Betulinic acid methyl ester is a lupane-type triterpenoid and an esterified version of betulinic acid that has been found in Helicteres hirsuta and has diverse biological activities. It inhibits HIV-1 reverse transcriptase (IC50 = 11 μM). Betulinic acid methyl ester is active against L. braziliensis and T. cruzi (IC50s = 69.9 and 93.3 μM, respectively). It induces melanogenesis in (EC50 = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC50 = 4.9 μM). Betulinic acid methyl ester is cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC50s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively).

Uses

Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity[1].

Definition

ChEBI: Betulinic acid methyl ester is a triterpenoid.

Biological Activity

Betulinic acid methyl ester is a natural compound extracted from the bark of the birch tree with anti-inflammatory and antiprotozoal activity.  Studies have shown it to be a potent inhibitor of cancer cell growth in vitro and in vivo.  It has also been shown to have hypoglycaemic effects in mice.

References

[1] D B Domínguez-Carmona, et al. Antiprotozoal activity of betulinic acid derivatives. Phytomedicine. 2010 Apr;17(5):379-82. DOI:10.1016/j.phymed.2009.08.002

BETULINIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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BETULINIC ACID METHYL ESTER Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apin Chemicals Limited (UK)
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6184
Advantage
60
Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
Apin Chemicals Ltd.
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6807
Advantage
42
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View Lastest Price from BETULINIC ACID METHYL ESTER manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
BETULINIC ACID METHYL ESTER 2259-06-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-04

2259-06-5, BETULINIC ACID METHYL ESTERRelated Search:


  • BETULINIC ACID METHYL ESTER
  • 3B-HYDROXY-LUP-20(29)-EN-28-OIC ACID METHYL ESTER
  • Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3beta)-
  • Methylbetulinate
  • BETULINIC ACID METHYL ESTER hplc
  • BETULINIC ACID METHYLESTER WITH HPLC
  • Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3β)-
  • betulinate, Methyl
  • Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3)-
  • 2259-06-5
  • Tri-Terpenoids