2-Amino-5-bromo-4,6-dimethylpyrimidine
- Product Name
- 2-Amino-5-bromo-4,6-dimethylpyrimidine
- CAS No.
- 4214-57-7
- Chemical Name
- 2-Amino-5-bromo-4,6-dimethylpyrimidine
- Synonyms
- 5-BROMO-4,6-DIMETHYLPYRIMIDIN-2-AMINE;2-AMINO-5-BROMO-4,6-DIMETHYLPYRIMIDINE;2-Pyrimidinamine, 5-bromo-4,6-dimethyl-;5-BROMO-4,6-DIMETHYLPYRIMIDINE-2-YLAMINE;2-Amino-5-bromo-4,6-dimethylpyrimidine,98%;2-Amino-5-bromo-4,6-dimethylpyrimidine ISO 9001：2015 REACH
- CBNumber
- CB7323780
- Molecular Formula
- C6H8BrN3
- Formula Weight
- 202.05
- MOL File
- 4214-57-7.mol
2-Amino-5-bromo-4,6-dimethylpyrimidine Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- Chloroform (Slightly, Sonicated), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- InChI
- InChI=1S/C6H8BrN3/c1-3-5(7)4(2)10-6(8)9-3/h1-2H3,(H2,8,9,10)
- InChIKey
- ACJZZTRAZBNBGJ-UHFFFAOYSA-N
- SMILES
- C1(N)=NC(C)=C(Br)C(C)=N1
- CAS DataBase Reference
- 4214-57-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Hazard Note
- Irritant
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A602043
- Product name
- 2-Amino-5-bromo-4,6-dimethylpyrimidine
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FB140738
- Product name
- 5-Bromo-4,6-dimethylpyrimidin-2-amine
- Packaging
- 2g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- FB140738
- Product name
- 5-Bromo-4,6-dimethylpyrimidin-2-amine
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- U917
- Product name
- 2-Amino-5-bromo-4,6-dimethylpyrimidine
- Packaging
- 5g
- Price
- $154
- Updated
- 2021/12/16
- Product number
- 072102
- Product name
- 2-Amino-5-bromo-4,6-dimethylpyrimidine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $185
- Updated
- 2021/12/16
2-Amino-5-bromo-4,6-dimethylpyrimidine Chemical Properties,Usage,Production
Synthesis
767-15-7
4214-57-7
General procedure for the synthesis of 2-amino-4,6-dimethyl-5-bromopyrimidine from 2-amino-4,6-dimethylpyrimidine: To a stirred solution of 150 mL of acetonitrile containing 4.3 g (34.75 mmol) of 2-amino-4,6-dimethylpyrimidine, 6.15 g (52.12 mmol) of N-bromosuccinimide was added. The reaction mixture was stirred under argon protection at room temperature for 3 hours. Upon completion of the reaction, the precipitate formed was collected by filtration and dried to afford the target product 2-amino-4,6-dimethyl-5-bromopyrimidine as a white solid in a yield of 5.93 g (83% yield). The structure of the product was confirmed by 1H-NMR (CDCl3) δ 5.19 (br, 2H), 2.44 (s, 6H) and 13C-NMR (CDCl3) δ 166.28, 160.73, 109.60, 24.70.
References
[1] Patent: WO2011/103536, 2011, A1. Location in patent: Page/Page column 35-37
[2] ACS Medicinal Chemistry Letters, 2011, vol. 2, # 8, p. 608 - 613
[3] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 4, p. 969 - 978
[4] Synthetic Communications, 1991, vol. 21, # 7, p. 901 - 906
[5] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 20, p. 5139 - 5143
2-Amino-5-bromo-4,6-dimethylpyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-5-bromo-4,6-dimethylpyrimidine manufacturers
- Product
- 2-Amino-5-bromo-4,6-dimethylpyrimidine 4214-57-7
- Price
- US $20.00-100.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2024-08-09
- Product
- 2-Amino-5-bromo-4,6-dimethylpyrimidine 4214-57-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-06
- Product
- 2-Amino-5-bromo-4,6-dimethylpyrimidine 4214-57-7
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-01-12