Chapso
- Product Name
- Chapso
- CAS No.
- 82473-24-3
- Chemical Name
- Chapso
- Synonyms
- CHAPSO;Hydroxy analog;CHAPSO extrapure;CHAPSO detergent;CHAPSO SIGMAULTRA;CHAPSO,ELECTROPHORESISGRADE;CHAPSO 96% For Biochemistry;CHAPSO Buffer extrapure, 99%;CHAPSO ELECTROPHORESIS REAGENT;CHAPSO - CAS 82473-24-3 - Calbiochem
- CBNumber
- CB7323821
- Molecular Formula
- C32H58N2O8S
- Formula Weight
- 630.88
- MOL File
- 82473-24-3.mol
Chapso Property
- Melting point:
- 184-186 °C(lit.)
- Density
- 1.0453 (rough estimate)
- refractive index
- 1.6900 (estimate)
- storage temp.
- -20°C
- solubility
- H2O: 10 mg/mL at 20 °C, clear, colorless
- form
- White solid
- color
- White crystalline
- Odor
- Odorless
- Water Solubility
- 10 g/l at 20 °C
- Merck
- 13,2052
- BRN
- 5842642
- InChIKey
- GUQQBLRVXOUDTN-PPDWFABINA-N
- CAS DataBase Reference
- 82473-24-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 220202
- Product name
- CHAPSO - CAS 82473-24-3 - Calbiochem
- Purity
- Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state.
- Packaging
- 1g
- Price
- $193
- Updated
- 2025/07/31
- Product number
- 220202
- Product name
- CHAPSO - CAS 82473-24-3 - Calbiochem
- Purity
- Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state.
- Packaging
- 5G
- Price
- $649
- Updated
- 2025/07/31
- Product number
- C4695
- Product name
- CHAPSO
- Purity
- BioXtra
- Packaging
- 500mg
- Price
- $182.05
- Updated
- 2025/07/31
- Product number
- C4695
- Product name
- CHAPSO
- Purity
- BioXtra
- Packaging
- 1g
- Price
- $323
- Updated
- 2025/07/31
- Product number
- C3649
- Product name
- CHAPSO
- Purity
- ≥98%
- Packaging
- 500mg
- Price
- $117.9
- Updated
- 2025/07/31
Chapso Chemical Properties,Usage,Production
Chemical Properties
Chapso is a white crystalline powder. It is a zwitterionic detergent similar to Chaps, however, Chapso is more soluble and particularly better for the solubilization of integral membrane proteins.
Uses
Chapso is a nondenaturing biological detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.
Application
3-(cholamidopropyl)(dimethylammonio)-2-hydroxy-1-propanesulfonate (CHAPSO) may be used in bicelle preparation for β2-adrenergic receptor reconstitution.
CHAPSO has been used:
in a study to assess the processes of liposome solubilization and reconstitution of two transport proteins
in a study to investigate a novel bicelle system for orienting macromolecules over a wide temperature range
as a mixture with dilauroyl phosphatidylcholine (DLPC) in solid-state nuclear magnetic resonance (NMR) technique to study membrane-associated proteins
A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.
General Description
CHAPSO is a non-denaturing zwitterionic bile salt derivative, derived from Chaps by the addition of a functional hydroxyl group.
Purification Methods
Dissolve this zwitterionic detergent (~ 60g) in 40% aqueous MeOH and stir it with the mixed-bed ion-exchange resin RG-501 x 8 (100g, Bio-Rad) until the pH of the supernatant is ~ 7. Filter off the resin and evaporate the filtrate to dryness under reduced pressure. Check for homogeneity by TLC on silica gel G in 95% MeOH/5% NH4OH and visualize the spot with iodine vapour (see CHAPS above). [Hjelmeland et al. Anal Biochem 130 72 1983, Matuo et al. Methods Enzymol 198 155 1991.]
Chapso Preparation Products And Raw materials
Raw materials
Preparation Products
Chapso Suppliers
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- Country
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View Lastest Price from Chapso manufacturers
- Product
- Chapso 82473-24-3
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 99%min
- Supply Ability
- 20000gs
- Release date
- 2025-09-10
- Product
- CHAPSO 82473-24-3
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- ≥98.0%
- Supply Ability
- 10kg/month
- Release date
- 2021-09-27
- Product
- 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate 82473-24-3
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2022-09-20