ChemicalBook > CAS DataBase List > Chapso

Chapso

Product Name: Chapso
CAS No.: 82473-24-3
Chemical Name: Chapso
Synonyms: CHAPSO;Hydroxy analog;CHAPSO extrapure;CHAPSO detergent;CHAPSO SIGMAULTRA;CHAPSO,ELECTROPHORESISGRADE;CHAPSO 96% For Biochemistry;CHAPSO Buffer extrapure, 99%;CHAPSO ELECTROPHORESIS REAGENT;CHAPSO - CAS 82473-24-3 - Calbiochem
CBNumber: CB7323821
Molecular Formula: C32H58N2O8S
Formula Weight: 630.88
MOL File: 82473-24-3.mol

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Chapso Property

Melting point:: 184-186 °C(lit.)
Density: 1.0453 (rough estimate)
refractive index: 1.6900 (estimate)
storage temp.: -20°C
solubility: H₂O: 10 mg/mL at 20 °C, clear, colorless
form: White solid
color: White crystalline
Odor: Odorless
Water Solubility: 10 g/l at 20 °C
Merck: 13,2052
BRN: 5842642
InChIKey: GUQQBLRVXOUDTN-PPDWFABINA-N
CAS DataBase Reference: 82473-24-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 3-10
HS Code: 2924297099

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 220202
Product name: CHAPSO - CAS 82473-24-3 - Calbiochem
Purity: Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state.
Packaging: 1g
Price: $193
Updated: 2025/07/31

Sigma-Aldrich

Product number: 220202
Product name: CHAPSO - CAS 82473-24-3 - Calbiochem
Purity: Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state.
Packaging: 5G
Price: $649
Updated: 2025/07/31

Sigma-Aldrich

Product number: C4695
Product name: CHAPSO
Purity: BioXtra
Packaging: 500mg
Price: $182.05
Updated: 2025/07/31

Sigma-Aldrich

Product number: C4695
Product name: CHAPSO
Purity: BioXtra
Packaging: 1g
Price: $323
Updated: 2025/07/31

Sigma-Aldrich

Product number: C3649
Product name: CHAPSO
Purity: ≥98%
Packaging: 500mg
Price: $117.9
Updated: 2025/07/31

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Chapso Chemical Properties,Usage,Production

Chemical Properties

Chapso is a white crystalline powder. It is a zwitterionic detergent similar to Chaps, however, Chapso is more soluble and particularly better for the solubilization of integral membrane proteins.

Uses

Chapso is a nondenaturing biological detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.

Application

3-(cholamidopropyl)(dimethylammonio)-2-hydroxy-1-propanesulfonate (CHAPSO) may be used in bicelle preparation for β2-adrenergic receptor reconstitution.
CHAPSO has been used:
in a study to assess the processes of liposome solubilization and reconstitution of two transport proteins
in a study to investigate a novel bicelle system for orienting macromolecules over a wide temperature range
as a mixture with dilauroyl phosphatidylcholine (DLPC) in solid-state nuclear magnetic resonance (NMR) technique to study membrane-associated proteins
A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.

General Description

CHAPSO is a non-denaturing zwitterionic bile salt derivative, derived from Chaps by the addition of a functional hydroxyl group.

Purification Methods

Dissolve this zwitterionic detergent (~ 60g) in 40% aqueous MeOH and stir it with the mixed-bed ion-exchange resin RG-501 x 8 (100g, Bio-Rad) until the pH of the supernatant is ~ 7. Filter off the resin and evaporate the filtrate to dryness under reduced pressure. Check for homogeneity by TLC on silica gel G in 95% MeOH/5% NH4OH and visualize the spot with iodine vapour (see CHAPS above). [Hjelmeland et al. Anal Biochem 130 72 1983, Matuo et al. Methods Enzymol 198 155 1991.]

Chapso Preparation Products And Raw materials

Raw materials

Preparation Products

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Chapso Suppliers

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View Lastest Price from Chapso manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.

Product: Chapso 82473-24-3
Price: US $0.00/g
Min. Order: 1g
Purity: 99%min
Supply Ability: 20000gs
Release date: 2025-09-10

WUHAN FORTUNA CHEMICAL CO., LTD

Product: CHAPSO 82473-24-3
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: ≥98.0%
Supply Ability: 10kg/month
Release date: 2021-09-27

Hebei Chuanghai Biotechnology Co., Ltd

Product: 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate 82473-24-3
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2022-09-20

82473-24-3, ChapsoRelated Search:

N,N-Dimethyl-1,4-phenylenediamine 4-Amino-benzenesulfonic acid monosodium salt Sulfanilic acid Sulfamic acid monosodium salt Nickel bis(sulphamidate) Sodium allylsulfonate Sulfamic acid CHAPS CHLOROPHOSPHONAZO III Cocamidopropyl hydroxysultaine N-[3-(DIMETHYLAMINO)PROPYL]STEARAMIDE Cholesterol LAURYLAMINO PROPYLAMINE 3-(Cholamidopropyl)-1,1-dimethamine NDSB-195 Chapso N-(3-COCOAMIDOPROPYL)-N,N-DIMETHYL-N-(3-SULFOPROPYL)AMMONIUM BETAINE N-(3-aminopropyl)stearamide

CHAPSO

3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-2-HYDROXY-1-PROPANESULFONATE

3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-2-HYDROXY-1-PROPANE SULPHONATE

1-Propanaminium, 2-hydroxy-N,N-dimethyl-3-sulfo-N-3-(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-ylaminopropyl-, inner salt

CHAPSO,ELECTROPHORESISGRADE

3-((3-cholamidopropyl)dimethylammonio)-2-hydroxy-

CHAPSO 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate

CHAPSO SIGMAULTRA

CHAPSO ELECTROPHORESIS REAGENT

CHAPSO extrapure

3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-2-HYDROXY-1-PROPANESULPHONATE (ULTRAPURE)

3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulphonate (Ultrapure) >99.0%

3-[(3-CholaMidopropyl)diMethylaMMonio]-2-hydroxy-1-propanesulfonate (CHAPSO)

CHAPSO Vetec(TM) reagent grade, >=98%

Hydroxy analog

CHAPSO, 3-[(3-Chloamidopropyl)dimethyl- ammonio]-2- hydroxy-1-propanesulfonate

CHLOROFORM: ISOAMYL ALCOHOL 24:1 BIOTECH

CHAPSO - CAS 82473-24-3 - Calbiochem

3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]-2-hydroxypropane-1-sulfonate

CHAPSO detergent

3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate ISO 9001：2015 REACH

3-[(3-Cholami dopropy1) dime thylammonio]-2-hydroxy-1-propanesulfonate

3-[(3-cholamine propyl) dimethylamino] -2-hydroxy-1-propanesulfonic acid internal salt

3-[(3-Cholylamine propyl)dimethylamino]-2-hydroxy-1-propanesulfonate

3-[(3-Cholesterolaminopropyl)dimethylamino]-2-hydroxy-1-propanesulfonic acid

CHAPSO 96% For Biochemistry

CHAPSO Buffer extrapure, 99%

3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxypropanesulfonate

CHAPSO - CAS 82473-24-3 - Calbiochem[220202]

3-[(3-Chloamidopropyl)dimethyl-ammonio]-2-hydroxy-1-propanesulfonate

82473-24-3

2473-24-3

C32H59N2O8S

C32H58N2O5S

C32H58N2O8S

BioChemical

Detergents

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