ChemicalBook > CAS DataBase List > Chapso

Chapso

Product Name
Chapso
CAS No.
82473-24-3
Chemical Name
Chapso
Synonyms
CHAPSO;Hydroxy analog;CHAPSO extrapure;CHAPSO detergent;CHAPSO SIGMAULTRA;CHAPSO,ELECTROPHORESISGRADE;CHAPSO 96% For Biochemistry;CHAPSO Buffer extrapure, 99%;CHAPSO ELECTROPHORESIS REAGENT;CHAPSO - CAS 82473-24-3 - Calbiochem
CBNumber
CB7323821
Molecular Formula
C32H58N2O8S
Formula Weight
630.88
MOL File
82473-24-3.mol
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Chapso Property

Melting point:
184-186 °C(lit.)
Density 
1.0453 (rough estimate)
refractive index 
1.6900 (estimate)
storage temp. 
-20°C
solubility 
H2O: 10 mg/mL at 20 °C, clear, colorless
form 
White solid
color 
White crystalline
Odor
Odorless
Water Solubility 
10 g/l at 20 °C
Merck 
13,2052
BRN 
5842642
CAS DataBase Reference
82473-24-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
F 
3-10
HS Code 
2924297099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
220202
Product name
CHAPSO - CAS 82473-24-3 - Calbiochem
Purity
Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state.
Packaging
1g
Price
$177
Updated
2024/03/01
Sigma-Aldrich
Product number
220202
Product name
CHAPSO - CAS 82473-24-3 - Calbiochem
Purity
Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state.
Packaging
5G
Price
$598
Updated
2024/03/01
Sigma-Aldrich
Product number
C4695
Product name
CHAPSO
Purity
BioXtra
Packaging
500mg
Price
$214
Updated
2024/03/01
Sigma-Aldrich
Product number
C4695
Product name
CHAPSO
Purity
BioXtra
Packaging
1g
Price
$304
Updated
2024/03/01
Sigma-Aldrich
Product number
C3649
Product name
CHAPSO
Purity
≥98%
Packaging
500mg
Price
$122
Updated
2024/03/01
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Chapso Chemical Properties,Usage,Production

Chemical Properties

Chapso is a white crystalline powder. It is a zwitterionic detergent similar to Chaps, however, Chapso is more soluble and particularly better for the solubilization of integral membrane proteins.

Uses

Chapso is a nondenaturing biological detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.

Application

3-(cholamidopropyl)(dimethylammonio)-2-hydroxy-1-propanesulfonate (CHAPSO) may be used in bicelle preparation for β2-adrenergic receptor reconstitution.
CHAPSO has been used:
in a study to assess the processes of liposome solubilization and reconstitution of two transport proteins
in a study to investigate a novel bicelle system for orienting macromolecules over a wide temperature range
as a mixture with dilauroyl phosphatidylcholine (DLPC) in solid-state nuclear magnetic resonance (NMR) technique to study membrane-associated proteins
A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.

General Description

CHAPSO is a non-denaturing zwitterionic bile salt derivative, derived from Chaps by the addition of a functional hydroxyl group.

Purification Methods

Dissolve this zwitterionic detergent (~ 60g) in 40% aqueous MeOH and stir it with the mixed-bed ion-exchange resin RG-501 x 8 (100g, Bio-Rad) until the pH of the supernatant is ~ 7. Filter off the resin and evaporate the filtrate to dryness under reduced pressure. Check for homogeneity by TLC on silica gel G in 95% MeOH/5% NH4OH and visualize the spot with iodine vapour (see CHAPS above). [Hjelmeland et al. Anal Biochem 130 72 1983, Matuo et al. Methods Enzymol 198 155 1991.]

Chapso Preparation Products And Raw materials

Raw materials

Preparation Products

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Chapso Suppliers

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View Lastest Price from Chapso manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
CHAPSO 82473-24-3
Price
US $0.00-0.00/g
Min. Order
1g
Purity
≥98.0%
Supply Ability
10kg/month
Release date
2021-09-27
Apeloa production Co.,Limited
Product
CHAPSO 82473-24-3
Price
US $0.80/g
Min. Order
1g
Purity
99%
Supply Ability
20000
Release date
2024-06-05
Hebei Yanxi Chemical Co., Ltd.
Product
CHAPSO 82473-24-3
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-27

82473-24-3, ChapsoRelated Search:

N,N-Dimethyl-1,4-phenylenediamine 4-Amino-benzenesulfonic acid monosodium salt Sulfanilic acid Sulfamic acid monosodium salt Nickel bis(sulphamidate) Sodium allylsulfonate Sulfamic acid CHAPS CHLOROPHOSPHONAZO III Cocamidopropyl hydroxysultaine N-[3-(DIMETHYLAMINO)PROPYL]STEARAMIDE Cholesterol LAURYLAMINO PROPYLAMINE 3-(Cholamidopropyl)-1,1-dimethamine NDSB-195 Chapso N-(3-COCOAMIDOPROPYL)-N,N-DIMETHYL-N-(3-SULFOPROPYL)AMMONIUM BETAINE N-(3-aminopropyl)stearamide

  • CHAPSO
  • 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-2-HYDROXY-1-PROPANESULFONATE
  • 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-2-HYDROXY-1-PROPANE SULPHONATE
  • 1-Propanaminium, 2-hydroxy-N,N-dimethyl-3-sulfo-N-3-(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-ylaminopropyl-, inner salt
  • CHAPSO,ELECTROPHORESISGRADE
  • 3-((3-cholamidopropyl)dimethylammonio)-2-hydroxy-
  • CHAPSO 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
  • CHAPSO SIGMAULTRA
  • CHAPSO ELECTROPHORESIS REAGENT
  • CHAPSO extrapure
  • 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-2-HYDROXY-1-PROPANESULPHONATE (ULTRAPURE)
  • 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulphonate (Ultrapure) >99.0%
  • 3-[(3-CholaMidopropyl)diMethylaMMonio]-2-hydroxy-1-propanesulfonate (CHAPSO)
  • CHAPSO Vetec(TM) reagent grade, >=98%
  • Hydroxy analog
  • CHAPSO, 3-[(3-Chloamidopropyl)dimethyl- ammonio]-2- hydroxy-1-propanesulfonate
  • CHLOROFORM: ISOAMYL ALCOHOL 24:1 BIOTECH
  • CHAPSO - CAS 82473-24-3 - Calbiochem
  • 3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]-2-hydroxypropane-1-sulfonate
  • CHAPSO detergent
  • 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate ISO 9001：2015 REACH
  • 3-[(3-Cholami dopropy1) dime thylammonio]-2-hydroxy-1-propanesulfonate
  • CHAPSO Buffer extrapure, 99%
  • 3-[(3-cholamine propyl) dimethylamino] -2-hydroxy-1-propanesulfonic acid internal salt
  • 3-[(3-Cholylamine propyl)dimethylamino]-2-hydroxy-1-propanesulfonate
  • 3-[(3-Cholesterolaminopropyl)dimethylamino]-2-hydroxy-1-propanesulfonic acid
  • CHAPSO 96% For Biochemistry
  • 82473-24-3
  • 2473-24-3
  • C32H59N2O8S
  • C32H58N2O5S
  • C32H58N2O8S
  • BioChemical
  • Detergents
  • Zwitterionic
  • detergent
  • Glycon Biochem