A[5']P5[5']A AMMONIUM SALT
- Product Name
- A[5']P5[5']A AMMONIUM SALT
- CAS No.
- 102783-61-9
- Chemical Name
- A[5']P5[5']A AMMONIUM SALT
- Synonyms
- A[5']P5[5']A AMMONIUM SALT;A[5']P5[5']A PENTAAMMONIUM SALT;Diadenosine pentaphosphate pentaammonium;P1 P5-DI(ADENOSINE-5') PENTAPHOSPHATE &;DIADENOSINE PENTAPHOSPHATE AMMONIUM SALT;DIADENOSINE PENTAPHOSPHATE PENTAAMMONIUM SALT;P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATE*AM MONIUM;P1,P5-Di(adenosine-5') pentaphosphate pentaammonium;P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATE AMMONIUM SALT;P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATE PENTAAMMONIUM SALT
- CBNumber
- CB7323942
- Molecular Formula
- C20H44N15O22P5
- Formula Weight
- 1001.52
- MOL File
- 102783-61-9.mol
A[5']P5[5']A AMMONIUM SALT Property
- storage temp.
- -20°C
- solubility
- H2O: 50 mg/mL
- form
- powder
- color
- white with faint yellow cast
- biological source
- synthetic (organic)
- Water Solubility
- H2O: 50mg/mL
Safety
- WGK Germany
- 3
- F
- 10-21
N-Bromosuccinimide Price
- Product number
- D8013
- Product name
- P1,P5-Di(adenosine-5′) pentaphosphate ammonium salt
- Purity
- ≥95% (HPLC), powder
- Packaging
- 10mg
- Price
- $201
- Updated
- 2025/07/31
- Product number
- D8013
- Product name
- P1,P5-Di(adenosine-5′) pentaphosphate ammonium salt
- Purity
- ≥95% (HPLC), powder
- Packaging
- 50mg
- Price
- $705
- Updated
- 2025/07/31
- Product number
- D8013
- Product name
- P1,P5-Di(adenosine-5′) pentaphosphate ammonium salt
- Purity
- ≥95% (HPLC), powder
- Packaging
- 25mg
- Price
- $384
- Updated
- 2025/07/31
- Product number
- NUC0002311
- Product name
- P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATE PENTAAMMONIUM SALT
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $714.67
- Updated
- 2021/12/16
- Product number
- NUC0002311
- Product name
- P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATE PENTAAMMONIUM SALT
- Purity
- 95.00%
- Packaging
- 25MG
- Price
- $822.85
- Updated
- 2021/12/16
A[5']P5[5']A AMMONIUM SALT Chemical Properties,Usage,Production
Uses
Diadenosine pentaphosphate pentaammonium is an endogenous vasoactive purine dinucleotide which has been isolated from thrombocytes. Diadenosine polyphosphates (ApnA, n=2–7) have been identified as constituents of secretory vesicles such as in platelets, chromaffin cells, Torpedo synaptic terminals and brain synaptosomes[1][2].
Biochem/physiol Actions
A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In heart, it increases contractile force and action potential duration, and shows an anti-β-adrenergic effect.
IC 50
Human Endogenous Metabolite
References
[1] L Giraldez, et al. Adenosine triphosphate and diadenosine pentaphosphate induce [Ca(2+)](i) increase in rat basal ganglia aminergic terminals. J Neurosci Res. 2001 Apr 15;64(2):174-82. DOI:10.1002/jnr.1063
[2] Jesús Pintor, et al. Presence of diadenosine polyphosphates in human tears. Pflugers Arch. 2002 Jan;443(3):432-6. DOI:10.1007/s004240100696
A[5']P5[5']A AMMONIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
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