Aluminon
- Product Name
- Aluminon
- CAS No.
- 569-58-4
- Chemical Name
- Aluminon
- Synonyms
- ATA;AURINTRICARBOXYLIC ACID AMMONIUM SALT;AURINTRICARBOXYLIC ACID AMMONIUM SALT, A CS;lysofon;ALUMINON;CI 43810;alactone;ALUMINONE;AluminoneGr;CI NO 43810
- CBNumber
- CB0413969
- Molecular Formula
- C22H17NO9
- Formula Weight
- 439.38
- MOL File
- 569-58-4.mol
Aluminon Property
- Melting point:
- 220-225 °C (dec.)(lit.)
- Boiling point:
- 573.92°C (rough estimate)
- Density
- 1.4414 (rough estimate)
- refractive index
- 1.6300 (estimate)
- storage temp.
- room temp
- solubility
- DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 100 μg/ml
- Colour Index
- 43810
- form
- powder
- color
- Deep red
- PH
- 5.3 (10g/l, H2O, 20°C)
- Water Solubility
- 800 g/L (20 ºC)
- Merck
- 14,322
- BRN
- 3900820
- Stability:
- Stable.
- CAS DataBase Reference
- 569-58-4
- EPA Substance Registry System
- Benzoic acid, 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-2-hydroxy-, triammonium salt (569-58-4)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/38-36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 2
- RTECS
- GU4800000
- TSCA
- Yes
- HS Code
- 29189090
- Toxicity
- LD50 orally in Rabbit: 9000 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- A36883
- Product name
- Aurintricarboxylic acid ammonium salt
- Purity
- ACS reagent
- Packaging
- 25g
- Price
- $71.8
- Updated
- 2024/03/01
- Product number
- A0885
- Product name
- Aurintricarboxylic acid ammonium salt
- Purity
- powder
- Packaging
- 25g
- Price
- $94
- Updated
- 2024/03/01
- Product number
- 1.00128
- Product name
- Aurin tricarboxylic acid ammonium salt
- Purity
- GR for analysis (reagent for aluminium) ACS
- Packaging
- 10g
- Price
- $842
- Updated
- 2024/03/01
- Product number
- A0240
- Product name
- Aluminon (mixture of isomers)
- Packaging
- 5g
- Price
- $70
- Updated
- 2024/03/01
- Product number
- A0240
- Product name
- Aluminon (mixture of isomers)
- Packaging
- 25g
- Price
- $279
- Updated
- 2024/03/01
Aluminon Chemical Properties,Usage,Production
Chemical Properties
dark red crystalline powder
Uses
It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.
Uses
Aluminon can used as a reagent for aluminum in solution. It is also Forms brilliantly colored lakes with aluminum, chromium, iron, beryllium. Generally used for the detection and colorimetric estimation of aluminum in water, foods, tissues. Cf. Scherrer, Mogerman, J. Res. Natl. Bur. Stand. 21, 105 (1938).
Definition
ChEBI: An ammonium salt that is the ammonium salt of 3,3'-[(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methylene]bis(6-hydroxybenzoic acid). A dye commonly used to detect the presence of the aluminium ion in an aqueous solution.
Biochem/physiol Actions
Aurintricarboxylic acid readily polymerizes in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types. Its neuroprotective effect, perhaps due to its ability to prevent down-regulation of Ca2+ impermeable GluR2 receptors or to its ability to inhibit calpain, a Ca2+-activated protease that is activated during apoptosis.
Safety Profile
Human reproductive effects by ingestion: changes in male fertility. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NH3 and NOx,.
Aluminon Preparation Products And Raw materials
Raw materials
Preparation Products
Aluminon Suppliers
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View Lastest Price from Aluminon manufacturers
- Product
- Aurintricarboxylic acid ammonium salt 569-58-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2020-01-16
- Product
- Aluminon 569-58-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- Aluminon 569-58-4
- Price
- US $1.00/KG
- Min. Order
- 1G
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-08-13