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Aluminon

Product Name
Aluminon
CAS No.
569-58-4
Chemical Name
Aluminon
Synonyms
ATA;AURINTRICARBOXYLIC ACID AMMONIUM SALT;AURINTRICARBOXYLIC ACID AMMONIUM SALT, A CS;lysofon;ALUMINON;CI 43810;alactone;ALUMINONE;AluminoneGr;CI NO 43810
CBNumber
CB0413969
Molecular Formula
C22H17NO9
Formula Weight
439.38
MOL File
569-58-4.mol
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Aluminon Property

Melting point:
220-225 °C (dec.)(lit.)
Boiling point:
573.92°C (rough estimate)
Density 
1.4414 (rough estimate)
refractive index 
1.6300 (estimate)
storage temp. 
room temp
solubility 
DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 100 μg/ml
Colour Index 
43810
form 
powder
color 
Deep red
PH
5.3 (10g/l, H2O, 20°C)
Water Solubility 
800 g/L (20 ºC)
Merck 
14,322
BRN 
3900820
Stability:
Stable.
CAS DataBase Reference
569-58-4
EPA Substance Registry System
Benzoic acid, 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-2-hydroxy-, triammonium salt (569-58-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/38-36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
2
RTECS 
GU4800000
TSCA 
Yes
HS Code 
29189090
Toxicity
LD50 orally in Rabbit: 9000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A36883
Product name
Aurintricarboxylic acid ammonium salt
Purity
ACS reagent
Packaging
25g
Price
$71.8
Updated
2024/03/01
Sigma-Aldrich
Product number
A0885
Product name
Aurintricarboxylic acid ammonium salt
Purity
powder
Packaging
25g
Price
$94
Updated
2024/03/01
Sigma-Aldrich
Product number
1.00128
Product name
Aurin tricarboxylic acid ammonium salt
Purity
GR for analysis (reagent for aluminium) ACS
Packaging
10g
Price
$842
Updated
2024/03/01
TCI Chemical
Product number
A0240
Product name
Aluminon (mixture of isomers)
Packaging
5g
Price
$70
Updated
2024/03/01
TCI Chemical
Product number
A0240
Product name
Aluminon (mixture of isomers)
Packaging
25g
Price
$279
Updated
2024/03/01
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Aluminon Chemical Properties,Usage,Production

Chemical Properties

dark red crystalline powder

Uses

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

Uses

Aluminon can used as a reagent for aluminum in solution. It is also Forms brilliantly colored lakes with aluminum, chromium, iron, beryllium. Generally used for the detection and colorimetric estimation of aluminum in water, foods, tissues. Cf. Scherrer, Mogerman, J. Res. Natl. Bur. Stand. 21, 105 (1938).

Definition

ChEBI: An ammonium salt that is the ammonium salt of 3,3'-[(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methylene]bis(6-hydroxybenzoic acid). A dye commonly used to detect the presence of the aluminium ion in an aqueous solution.

Biochem/physiol Actions

Aurintricarboxylic acid readily polymerizes in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types. Its neuroprotective effect, perhaps due to its ability to prevent down-regulation of Ca2+ impermeable GluR2 receptors or to its ability to inhibit calpain, a Ca2+-activated protease that is activated during apoptosis.

Safety Profile

Human reproductive effects by ingestion: changes in male fertility. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NH3 and NOx,.

Aluminon Preparation Products And Raw materials

Raw materials

Salicylic acid filter paper Formaldehyde NITRIC OXIDE

Preparation Products

Misoprostol
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Aluminon Suppliers

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View Lastest Price from Aluminon manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Aurintricarboxylic acid ammonium salt 569-58-4
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%
Supply Ability
2000tons
Release date
2020-01-16
Zhuozhou Wenxi import and Export Co., Ltd
Product
Aluminon 569-58-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
Aluminon 569-58-4
Price
US $1.00/KG
Min. Order
1G
Purity
99%
Supply Ability
100KG
Release date
2018-08-13

569-58-4, AluminonRelated Search:

2'-Hydroxy-3-phenylpropiophenone Salicylic acid Folic acid Citric acid Butylparaben 3-Hydroxybenzoic acid Hyaluronic acid Methylparaben Isopropylparaben Ethyl 2-(Chlorosulfonyl)acetate 1.10-Phenanthroline 4-Hydroxybenzoic acid Ascoric Acid Sorbic acid ROSOLIC ACID 5-PHENYLPENTA-2,4-DIENOIC ACID 5,5'-Methylenedisalicylic acid 5-Methylsalicylic acid

  • TRI-AMMONIUM AURINE-TRICARBOXYLATE
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  • ammonium aurinetricarboxylate
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  • AURINTRICARBOXYLICACIDTRIAMMONIUMSALT,REAGENT,ACS
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  • Ammonium auritricarboxylate ATA Triammonium aurinetricarboxylate triammonium salt Ammonium aurintricarboxylate aurintricarboxylic acid ammonium salt Aluminon(C.1.No.43810) aurintricarboxylic acid triammonium salt
  • c.i.mordantviolet39,triammoniumsalt
  • lysofon
  • triammoniumaurintricarboxylate
  • triammoniumsalt
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  • Aurin Tricarboxylic Acid, Triammonium Salt, Reagent
  • 1,4-Cyclohexadiene-1-carboxylic acid, 3-(bis(3-carboxy-4-hydroxyphenyl)methylene)-6-oxo-, triammonium salt
  • Triazanium 5-[(3-carboxylato-4-hydroxyphenyl)-(3-carboxylato-4-oxo-1-cyclohexa-2,5-dienyl)methyl]-2-hydroxybenzoate
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  • CHROME VIOLET CG ALUMINON
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  • CI NO 43810
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  • AluMinon (Mixture of isoMers)
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  • Benzoic acid,3,3'-[(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis[6-hydroxy-,ammonium salt (1:3)
  • triammonium 3,3'-[(3-carboxylato-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis(6-hydroxybenzoate)
  • Aluminon ISO 9001：2015 REACH
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