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ROSOLIC ACID

Product Name
ROSOLIC ACID
CAS No.
603-45-2
Chemical Name
ROSOLIC ACID
Synonyms
AURIN;RosoL;AURINE;CORALLIN;CI 43800;AURIN GR;Nsc 7805;Aurin 555;Rosolic aci;CI NO 43800
CBNumber
CB0296269
Molecular Formula
C19H14O3
Formula Weight
290.31
MOL File
603-45-2.mol
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ROSOLIC ACID Property

Melting point:
309°C (decompose)
Boiling point:
372.4°C (rough estimate)
Density 
1.2497 (rough estimate)
refractive index 
1.4200 (estimate)
storage temp. 
Store at room temperature.
solubility 
Practically insoluble in water, benzene; freely soluble in ethanol
form 
Crystalline Powder
Colour Index 
43800
pka
6.98(at 25℃)
color 
Red-brown to brownish-red
PH Range
6.8(YELLOW)--8.2(RED)
Water Solubility 
Soluble in alcohol, sodium hydroxide, potassium hydroxide and strong acids. Insoluble in water.
λmax
534.6nm, 479.5nm, 482nm
Merck 
14,881
BRN 
2055205
Stability:
Stable. Incompatible with strong oxidizing agents.
Major Application
electrorheological materials, films patterning, antireflective coatings, thermochromic materials, photoresists, film patterning, recording materials, lithium battery, semiconductors, printing materials, inks, corrosion inhibitors, adhesives, drugs, detecting viable cells, treatment of Alzheimer’s disease
CAS DataBase Reference
603-45-2
EPA Substance Registry System
2,5-Cyclohexadien-1-one, 4-[bis(4-hydroxyphenyl)methylene]- (603-45-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-36/38
Safety Statements 
26-36-37/39
WGK Germany 
3
TSCA 
Yes
HS Code 
29145090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
861324
Product name
p-Rosolic acid
Purity
Dye content 85%
Packaging
25g
Price
$129
Updated
2024/03/01
Sigma-Aldrich
Product number
861324
Product name
p-Rosolic acid
Purity
Dye content 85%
Packaging
100g
Price
$447
Updated
2024/03/01
Sigma-Aldrich
Product number
RX0175
Product name
Rosolic Acid
Packaging
25g
Price
$143
Updated
2023/01/07
TCI Chemical
Product number
A0598
Product name
Pararosolic Acid
Packaging
25g
Price
$65
Updated
2024/03/01
Alfa Aesar
Product number
B21737
Product name
Rosolic acid
Packaging
25g
Price
$79.4
Updated
2024/03/01
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ROSOLIC ACID Chemical Properties,Usage,Production

Chemical Properties

red crystals or powder

Uses

activates heme oxygenase, anti-oxidative stress, inhibits DNA fragmentation

Uses

A red coloring medium made from phenol or carbolic acid. It is soluble in alcohol and ether but insoluble in water. When fabrics were steeped in this solution, the color was nonactinic and therefore safe for darkrooms, windows, and doorways. Aurin was also mixed with water-soluble gums and brushed on the backs of collodion and silver bromide gelatin plates as an antihalation layer.

Uses

Rosolic acid is used as a pH indicator in the range from 5.0 to 6.8. It acts as an intermediate in the manufacturing dyes. It is involved in the activation of heme oxygenase and in the inhibition of DNA fragmentation. It finds application in the selective isolation of coliform bacteria.

Definition

ChEBI: Aurin is a diarylmethane.

Purification Methods

It forms green crystals with a metallic luster, but the colour depends on the solvent used. When recrystallised from brine (saturated aqueous NaCl) acidified with HCl, it forms red needles, but when recrystallised from EtO/AcOH, the crystals have a beetle iridescent green colour. It has been recrystallised from Me2CO (although it dissolves slowly), methyl ethyl ketone, 80-95% AcOH and from AcOH/*C6H6. An aqueous KOH solution is golden yellow, and a 70% H2SO4 solution is deep red in colour. An alternative purification is to dissolve this triphenylmethane dye in 1.5% of aqueous NH3, filter, and heat to 70-80o, then acidify with dilute AcOH by adding it slowly with vigorous stirring, whereby the aurin separates as a brick-red powder or as purplish crystals depending on the temperature and period of heating. Filter off the solid, wash it with H2O and a little dilute AcOH, then H2O again. Stir this solid with Et2O to remove any ketones and allow it to stand overnight in the Et2O, then filter and dry it in air then in a vacuum. [Gomberg & Snow J Am Chem Soc 47 202 1925, Baines & Driver J Chem Soc 123 1216 1923, UV: Burawoy Chem Ber 64 462 1941, Beilstein 8 IV 2646.]

ROSOLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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ROSOLIC ACID Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
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View Lastest Price from ROSOLIC ACID manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Pararosolic Acid 603-45-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
Aurin 603-45-2
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-25

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