ChemicalBook > CAS DataBase List > ROSOLIC ACID

ROSOLIC ACID

Product Name
ROSOLIC ACID
CAS No.
603-45-2
Chemical Name
ROSOLIC ACID
Synonyms
AURIN;RosoL;AURINE;CORALLIN;CI 43800;AURIN GR;Nsc 7805;Aurin 555;Rosolic aci;CI NO 43800
CBNumber
CB0296269
Molecular Formula
C19H14O3
Formula Weight
290.31
MOL File
603-45-2.mol
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ROSOLIC ACID Property

Melting point:
309°C (decompose)
Boiling point:
372.4°C (rough estimate)
Density 
1.2497 (rough estimate)
refractive index 
1.4200 (estimate)
storage temp. 
Store at room temperature.
solubility 
Practically insoluble in water, benzene; freely soluble in ethanol
form 
Crystalline Powder
Colour Index 
43800
pka
6.98(at 25℃)
color 
Red-brown to brownish-red
PH Range
6.8(YELLOW)--8.2(RED)
Water Solubility 
Soluble in alcohol, sodium hydroxide, potassium hydroxide and strong acids. Insoluble in water.
λmax
534.6nm, 479.5nm, 482nm
Merck 
14,881
BRN 
2055205
Stability:
Stable. Incompatible with strong oxidizing agents.
Major Application
electrorheological materials, films patterning, antireflective coatings, thermochromic materials, photoresists, film patterning, recording materials, lithium battery, semiconductors, printing materials, inks, corrosion inhibitors, adhesives, drugs, detecting viable cells, treatment of Alzheimer’s disease
CAS DataBase Reference
603-45-2
EPA Substance Registry System
2,5-Cyclohexadien-1-one, 4-[bis(4-hydroxyphenyl)methylene]- (603-45-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-36/38
Safety Statements 
26-36-37/39
WGK Germany 
3
TSCA 
Yes
HS Code 
29145090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
861324
Product name
p-Rosolic acid
Purity
Dye content 85%
Packaging
25g
Price
$129
Updated
2024/03/01
Sigma-Aldrich
Product number
861324
Product name
p-Rosolic acid
Purity
Dye content 85%
Packaging
100g
Price
$447
Updated
2024/03/01
Sigma-Aldrich
Product number
RX0175
Product name
Rosolic Acid
Packaging
25g
Price
$143
Updated
2023/01/07
TCI Chemical
Product number
A0598
Product name
Pararosolic Acid
Packaging
25g
Price
$65
Updated
2024/03/01
Alfa Aesar
Product number
B21737
Product name
Rosolic acid
Packaging
25g
Price
$79.4
Updated
2024/03/01
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ROSOLIC ACID Chemical Properties,Usage,Production

Chemical Properties

red crystals or powder

Uses

activates heme oxygenase, anti-oxidative stress, inhibits DNA fragmentation

Uses

A red coloring medium made from phenol or carbolic acid. It is soluble in alcohol and ether but insoluble in water. When fabrics were steeped in this solution, the color was nonactinic and therefore safe for darkrooms, windows, and doorways. Aurin was also mixed with water-soluble gums and brushed on the backs of collodion and silver bromide gelatin plates as an antihalation layer.

Uses

Rosolic acid is used as a pH indicator in the range from 5.0 to 6.8. It acts as an intermediate in the manufacturing dyes. It is involved in the activation of heme oxygenase and in the inhibition of DNA fragmentation. It finds application in the selective isolation of coliform bacteria.

Definition

ChEBI: Aurin is a diarylmethane.

Purification Methods

It forms green crystals with a metallic luster, but the colour depends on the solvent used. When recrystallised from brine (saturated aqueous NaCl) acidified with HCl, it forms red needles, but when recrystallised from EtO/AcOH, the crystals have a beetle iridescent green colour. It has been recrystallised from Me2CO (although it dissolves slowly), methyl ethyl ketone, 80-95% AcOH and from AcOH/*C6H6. An aqueous KOH solution is golden yellow, and a 70% H2SO4 solution is deep red in colour. An alternative purification is to dissolve this triphenylmethane dye in 1.5% of aqueous NH3, filter, and heat to 70-80o, then acidify with dilute AcOH by adding it slowly with vigorous stirring, whereby the aurin separates as a brick-red powder or as purplish crystals depending on the temperature and period of heating. Filter off the solid, wash it with H2O and a little dilute AcOH, then H2O again. Stir this solid with Et2O to remove any ketones and allow it to stand overnight in the Et2O, then filter and dry it in air then in a vacuum. [Gomberg & Snow J Am Chem Soc 47 202 1925, Baines & Driver J Chem Soc 123 1216 1923, UV: Burawoy Chem Ber 64 462 1941, Beilstein 8 IV 2646.]

ROSOLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ROSOLIC ACID manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Pararosolic Acid 603-45-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
Aurin 603-45-2
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-25

603-45-2, ROSOLIC ACIDRelated Search:

Aluminon Ammonium metavanadate Ferrous chloride Sodium thiocyanate Trimellitic Anhydride Phenolphthalein Potassium dichromate RHODIZONIC ACID DIHYDRATE ROSOLIC ACID AURINTRICARBOXYLIC ACID TIMTEC-BB SBB006515 P-ROSOLIC ACID SODIUM SALT AURINTRICARBOXYLIC ACID TRISODIUM SALT 4-[(4-hydroxy-3-methylphenyl)(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one SALOR-INT L162582-1EA

  • 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadienone, Aurin
  • 4,4'-Dihydroxyfuchsone
  • Corallin Spirit Soluble
  • Spirit Aurin
  • Rosolic acid (CI x 43800)
  • 4-(p,p′-Dihydroxybenzhydrylidine)-2,5-cyclohexadien-1-one
  • Corallin Aurin p-Rosolic Acid
  • Rosolic aci
  • 4-(bis(4-hydroxyphenyl)Methylene)cyclohexa-2,5-dienone
  • PARAROSOLIC ACID
  • P-ROSOLIC ACID
  • 4-[bis(4-hydroxyphenyl)methylene]-5-cyclohexadien-1-one
  • CORALLIN
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  • CORALLIN YELLOW
  • CI NO 43800
  • CI 43800
  • LABOTEST-BB LT00847601
  • AURIN
  • AURINE
  • 4-(Bis(4-hydroxyphenyl)
  • cyclohexa-2,5-dienone
  • 4-[BIS(4-HYDROXYPHENYL)METHYLENE]-2,5-CYCLOHEXADIEN-1-ONE
  • 4-[BIS(4-HYDROXYPHENYL)METHYLENE]-2,5-CYCLOHEXADIENONE
  • 4-[BIS-(P-HYDROXYPHENYL)METHYLENE]-2,5-CYCLO-HEXADIEN-1-ONE
  • ROSOLIC ACID INDICATOR
  • ROSOLIC ACID (C.I. 43800)
  • ROSOLIC ACID PRACTICAL GRADE
  • ROSOLIC ACID C.I. 43800 INDICATOR FOR MICROSCOPY
  • AURIN FOR MICROSCOPY (Rosolic Acid) C.I. No 43800
  • Para-ROSOLIC ACID INDICATOR
  • AURIN (C.I. 43800)
  • 4-[bis(p-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one
  • Roseolic acid
  • AURIN GR
  • RHODIZONIC ACID Dihydrate(P)
  • Aurine、Pararosolic acid
  • 2,5-cyclohexadien-1-one, 4-[bis(p-hydroxyphenyl)methylene]-
  • 4-(p,p′-dihydroxybenzhydrylidene)-2,5-cyclohexadien-1-one
  • 4-[bis(p-hydroxy- Aphenyl)methylene]-2,5-cyclohexadien-1-one
  • Aurin 555
  • Nsc 7805
  • Rosalic Acid
  • Spirit Aurine
  • p-Rosolic acid, indicator
  • 2,5-Cyclohexadien-1-one, 4-bis(4-hydroxyphenyl)methylene-
  • Aurin (p-rosolic acid)
  • RosoL
  • 4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one
  • Rosolic acid pH indicator solution
  • ROSOLIC ACID USP/EP/BP
  • Rosonic acid, indicator
  • TIANFUCHEM--High purity ROSOLIC ACID factory price
  • p-ROSOLIC ACID INDICATOR For Microscopy
  • 4-(Bis(4-hydroxyphenyl)methylene)cyclohexa-2,5-dien-1-one
  • AURIN (p-ROSALIC ACID)
  • Aurin (P-Rosolic Acid) For Microscopy
  • 603-45-2