AURINTRICARBOXYLIC ACID
- Product Name
- AURINTRICARBOXYLIC ACID
- CAS No.
- 4431-00-9
- Chemical Name
- AURINTRICARBOXYLIC ACID
- Synonyms
- ATA;SKL331;e)-6-oxo-;aluminonfreeacid;TIMTEC-BB SBB005410;AURINTRICARBONIC ACID;aurintricarboxylicaci;LABOTEST-BB LT00080677;AURINTRICARBOXYLIC ACID;aurinetricarboxylic acid
- CBNumber
- CB7463004
- Molecular Formula
- C22H14O9
- Formula Weight
- 422.34
- MOL File
- 4431-00-9.mol
AURINTRICARBOXYLIC ACID Property
- Melting point:
- 300 °C(lit.)
- Boiling point:
- 458.99°C (rough estimate)
- Density
- 1.3860 (rough estimate)
- refractive index
- 1.6230 (estimate)
- storage temp.
- +15C to +30C
- solubility
- 1 M NH4OH: 10 mg/mL
- form
- powder
- pka
- 2.20±0.20(Predicted)
- color
- dark red to brown
- Water Solubility
- Insoluble in water.
- BRN
- 2228904
- CAS DataBase Reference
- 4431-00-9(CAS DataBase Reference)
- EPA Substance Registry System
- Benzoic acid, 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-2-hydroxy- (4431-00-9)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A1895
- Product name
- Aurintricarboxylic acid
- Purity
- practical grade, ≥85% (titration), powder
- Packaging
- 5g
- Price
- $69.6
- Updated
- 2024/03/01
- Product number
- 189400
- Product name
- Aurintricarboxylic Acid
- Packaging
- 100mg
- Price
- $56.2
- Updated
- 2024/03/01
- Product number
- A15905
- Product name
- Aurintricarboxylic acid
- Packaging
- 5g
- Price
- $47
- Updated
- 2024/03/01
- Product number
- A15905
- Product name
- Aurintricarboxylic acid
- Packaging
- 25g
- Price
- $128.65
- Updated
- 2024/03/01
- Product number
- A1895
- Product name
- Aurintricarboxylic acid
- Purity
- practical grade, ≥85% (titration), powder
- Packaging
- 25g
- Price
- $240
- Updated
- 2024/03/01
AURINTRICARBOXYLIC ACID Chemical Properties,Usage,Production
Chemical Properties
deep red coarse crystalline powder
Uses
endonuclease inhibitor; apoptosis inhibitor, topoisomerase II inhibitor
Uses
Aurintricarboxylic acid is employed as a powerful inhibitor of cellular processes, including apoptosis, that are dependent on the formation of protein-nucleic acid complexes. It binds to a FGF and reduces its angiogenic activity. Aurintricarboxylic Acid has been shown to inhibit apoptotic cell death in various cell types induced by a variety of factors. It Inhibits protein-nucleic acid interactions. It stimulates the tyrosine phosphorylation of MAP kinases.
Definition
ChEBI: A member of the class of quinomethanes that is 3-methylidene-6-oxocyclohexa-1,4-diene-1-carboxylic acid in which the methylidene hydrogens are replaced by 4-carboxy-3-hydroxyphenyl groups. The trisodium salt is the biological stain 'chrome violet CG' while the triammonium salt is 'aluminon'.
Purification Methods
The acid is dissolved in aqueous NaOH, NaHSO3 solution is added until the colour is discharged and then the tricarboxylic acid is precipitated with HCl. [Heisig & Lauer Org Synth Coll Vol I 54 1941, Beilstein 10 IV 4161]. Do not extract the acid with hot water because it softens, forming a viscous mass. Make a solution in aqueous NH3. Aluminon is the NH4 salt.
AURINTRICARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from AURINTRICARBOXYLIC ACID manufacturers
- Product
- AURINTRICARBOXYLIC ACID 4431-00-9
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24
- Product
- AURINTRICARBOXYLIC ACID 4431-00-9
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24