ChemicalBook > CAS DataBase List > UNCARINE C

UNCARINE C

Product Name
UNCARINE C
CAS No.
5629-60-7
Chemical Name
UNCARINE C
Synonyms
UNCARINE C;PTEROPODINE;Uncarine C-RM;Isospeciophylline;(20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester;methyl 1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate;methyl 1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate;2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester;Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3R,4'aS,5'aS,10'aS)-
CBNumber
CB7326387
Molecular Formula
C21H24N2O4
Formula Weight
368.43
MOL File
5629-60-7.mol
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UNCARINE C Property

Melting point:
217-219℃
Density 
1.33±0.1 g/cm3 (20 ºC 760 Torr)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Usbiological
Product number
361888
Product name
Uncarine C
Packaging
10mg
Price
$490
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004549
Product name
UNCARINE C
Purity
95.00%
Packaging
5MG
Price
$495.77
Updated
2021/12/16
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UNCARINE C Chemical Properties,Usage,Production

Description

Isolated from Uncaria pteropoda, this alkaloid is probably stereoisomeric withMitraphylline (q.v.). It forms colourless plates when crystallized from MeOH and has [α]29DJ 9 - 102.5° (c 1.0, CHC13). The ultraviolet spectrum in MeOH has an absorption maximum at 246 mp. with a shoulder at 280 mp.. A crystalline picrate, m.p. 143-6°C; [α]D - 9.6° (c 0.5, EtOH) and a methiodide, m.p. 209-211°C after softening at 204°C; [α]D - 149° (c 0.53, EtOH) have been prepared. A solution of the alkaloid in pyridine forms an equilibrium mixture with 70 per cent isopteropodine when heated.

Uses

Uncarine C is a compound extracted from Uncaria tomentosa leaves. The compounds extracted from these leaves have exhibited immunomodulating, antiinflammatory and anti-cancer activity, attributed to the presence of tetra/pentacyclic oxindole alkaloids.

Definition

ChEBI: Uncarine C is a member of indolizines.

References

Yeoh, Chan, Morsingh., Tetrahedron Lett., 931 (1966)
Chan, Morsingh, Yeoh., 1. Chem. Soc., C, 2245 (1966)
Stereochemistry: Shamma et al., 1. Amer. Chem. Soc., 89, 1739, 2799 (1967)

UNCARINE C Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from UNCARINE C manufacturers

Career Henan Chemica Co
Product
UNCARINE C 5629-60-7
Price
US $2.20/KG
Min. Order
1KG
Purity
98%
Supply Ability
1KG/10KG/100KG
Release date
2020-10-29
Shaanxi Haibo Biotechnology Co., Ltd
Product
UNCARINE C 5629-60-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-24
Shaanxi Haibo Biotechnology Co., Ltd
Product
Peiminine 5629-60-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-24

5629-60-7, UNCARINE CRelated Search:


  • PTEROPODINE
  • UNCARINE C
  • (20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
  • 2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester
  • methyl 1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
  • methyl 1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
  • Isospeciophylline
  • Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3R,4'aS,5'aS,10'aS)-
  • Uncarine C-RM
  • 5629-60-7
  • C21H24N2O4