ANTI-PARP
- Product Name
- ANTI-PARP
- Chemical Name
- ANTI-PARP
- Synonyms
- Anti-RM1;ANTI-PARP;Anti-DDF1;Anti-PARP7;ANTI-PARP-1;Anti-PARP-7;Anti-PART14;Anti-TIPARP;ANTI-HUMAN PARP;ANTI-PARP(N-20)
- CBNumber
- CB7327283
- Formula Weight
- 0
- MOL File
- Mol file
ANTI-PARP Property
- storage temp.
- -20°C
- form
- buffered aqueous solution
N-Bromosuccinimide Price
- Product number
- SAB2102431
- Product name
- Anti-TIPARP antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μL
- Price
- $524
- Updated
- 2024/03/01
- Product number
- P7605
- Product name
- Anti-PARP antibody produced in rabbit
- Purity
- affinity isolated antibody, buffered aqueous solution
- Packaging
- 0.2mL
- Price
- $515
- Updated
- 2024/03/01
- Product number
- P248
- Product name
- Monoclonal Anti-PARP antibody produced in mouse
- Purity
- clone C-2-10, ascites fluid
- Packaging
- 50μl
- Price
- $764
- Updated
- 2024/03/01
- Product number
- HPA045168
- Product name
- Anti-PARP1 antibody produced in rabbit
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
- Packaging
- 100μL
- Price
- $514
- Updated
- 2024/03/01
- Product number
- AV33754
- Product name
- Anti-PARP1 antibody produced in rabbit
- Purity
- IgG fraction of antiserum
- Packaging
- 100μL
- Price
- $405
- Updated
- 2024/03/01
ANTI-PARP Chemical Properties,Usage,Production
Uses
Monoclonal Anti-PARP (Cleaved-Asp214) antibody has been used in western blotting and immunohistochemical staining.
Uses
Anti-poly (ADP-Ribose) polymerase is used for western blots, immunochemistry, immunofluorescence and immunoprecipitation.
General Description
Monoclonal Anti-PARP (mouse IgG1) is produced by immunizing mice with purified calf thymus poly (ADPribose) polymerase as the antigen. This antibody recognizes a 116kDa protein which corresponds to PARP and the 85kDa apoptosis induced cleavage product of prICE (proteinase resembling interleukin 1b-converting enzyme) and CPP32 (cysteine protease). It also recognizes PARP from mouse, rat, hamster and primate sources, but fails to detect avian PARP.
Poly (ADP-ribose) polymerase 1 (PARP1)/PARP is encoded by the gene mapped to human chromosome 1q42. It is a nuclear protein with molecular mass of 113kDa and is characterized with three functional domains. It belongs to the PARP superfamily.
Biochem/physiol Actions
PARP1 poly(ADP-ribose) polymerase 1) and its enzymatic product PAR controls cellular processes like DNA repair, chromatin remodeling, transcription and cell death. PARP1 regulates transcription. PARP1 can induce or block homologous recombination (HR).