3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

Product Name: 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
CAS No.: 1479-24-9
Chemical Name: 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
Synonyms: RMA-126;NSC 166423;ETHYL 2-FLUOROBENZOYLACETATE;Ethyl(2-Fluorobenzoyl)acetate>2-Fluorobenzoylacetic acid ethyl ester;2-[(2-fluorophenyl)-oxomethyl]butanoate;ETHYL 3-(2-FLUOROPHENYL)-3-OXOPROPANOATE;Ethyl 3-oxo-3-(2-fluorophenyl)propionate;Ethyl 3-(2-fluorophenyl)-3-oxo-propionate;Ethyl (2-fluorobenzoyl)acetate technical grade
CBNumber: CB7331507
Molecular Formula: C11H11FO3
Formula Weight: 210.2
MOL File: 1479-24-9.mol

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3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Property

Boiling point:: 124-125℃ (1.5 Torr)
Density: 1.164 g/mL at 25 °C(lit.)
refractive index: n20/D 1.516(lit.)
Flash point:: >230 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Liquid
pka: 10.03±0.46(Predicted)
color: Colorless to Light orange to Yellow

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Safety

WGK Germany: 3
HS Code: 2918.30.9000

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 225134
Product name: Ethyl (2-fluorobenzoyl)acetate
Purity: technical grade
Packaging: 1g
Price: $176
Updated: 2023/06/20

Sigma-Aldrich

Product number: 225134
Product name: Ethyl (2-fluorobenzoyl)acetate
Purity: technical grade
Packaging: 10g
Price: $1090
Updated: 2023/06/20

TCI Chemical

Product number: E1097
Product name: Ethyl (2-Fluorobenzoyl)acetate
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $114
Updated: 2025/07/31

TCI Chemical

Product number: E1097
Product name: Ethyl (2-Fluorobenzoyl)acetate
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $398
Updated: 2025/07/31

TRC

Product number: B124908
Product name: Ethyl3-(2-Fluorophenyl)-3-oxopropanoate
Packaging: 100mg
Price: $60
Updated: 2021/12/16

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3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Uses

Ethyl (2-fluorobenzoyl)acetate may be used in chemical synthesis.

Synthesis

64-17-5

223679-79-6

1479-24-9

GENERAL METHOD: An appropriate amount of diketone (9a or 9b) (0.3 mol) was mixed with ethanol (500 mL), heated to 80 °C and refluxed for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was removed by distillation under reduced pressure to give the target product ester (10a or 10b) in the form of a red oil. 7.10.1 Preparation of ethyl 3-(2-fluorophenyl)-3-oxopropanoate (10a): the product obtained was a red oily material in 85% yield; mass spectrum (ESI) m/z: 233.1 [M + Na]? , 443.1 [2M + Na]?

References

[1] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 11, p. 2843 - 2855
[2] Archiv der Pharmazie, 2013, vol. 346, # 7, p. 521 - 533
[3] Patent: EP2799437, 2014, A1. Location in patent: Paragraph 0057
[4] Patent: US2014/364431, 2014, A1. Location in patent: Paragraph 0188
[5] Patent: WO2017/37672, 2017, A1. Location in patent: Page/Page column 48

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Suppliers

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View Lastest Price from 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER manufacturers

Career Henan Chemical Co

Product: 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER 1479-24-9
Price: US $1.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 99%
Supply Ability: KG/T
Release date: 2019-12-18

1479-24-9, 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTERRelated Search:

3-OXO-PROPIONIC ACID ETHYL ESTER 2-CYANO-3-(4-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Ethyl (3-fluorobenzoyl)acetate 2-CYANO-3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER 3-(2,4-DICHLORO-5-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER 3-(4-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Ethyl 2,4,5-trifluorobenzoylacetate 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Ethyl (pentafluorobenzoyl)acetate Ethyl 2,3,4,5-tetrafluorobenzoyl acetate 5,8-DIFLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 5,6,7,8-TETRAFLUORO-2-METHYL-4-OXO-4H-CHROMENE-3-CARBOXYLIC ACID ETHYL ESTER

Ethyl 3-oxo-3-(2-fluorophenyl)propionate

NSC 166423

Ethyl (2-fluorobenzoyl)acetate technical grade

Ethyl 3-(2-fluorophenyl)-3-oxo-propionate

2-Fluorobenzoylacetic acid ethyl ester

3-Oxo-3-(2-fluorophenyl)propionic acid ethyl ester

β-Oxo-2-fluorobenzenepropanoic acid ethyl ester

Benzenepropanoic acid, 2-fluoro-b-oxo-, ethyl ester

2-[(2-fluorophenyl)-oxomethyl]butanoate

ETHYL 2-FLUOROBENZOYLACETATE

ETHYL 3-(2-FLUOROPHENYL)-3-OXOPROPANOATE

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

Ethyl(2-Fluorobenzoyl)acetate&gt

Benzenepropanoic acid, 2-fluoro-β-oxo-, ethyl ester

RMA-126

Benzenepropanoic acid, 2-fluoro-β-oxo-, ethyl ester

1479-24-9

Building Blocks

Carbonyl Compounds

C10 to C11

Organic Building Blocks

Esters

Aryl Fluorinated Building Blocks

Building Blocks

C10 to C11

C8-C12

Carbonyl Compounds

Chemical Synthesis

Fluorinated Building Blocks

Organic Building Blocks

Organic Fluorinated Building Blocks

Other Fluorinated Organic Building Blocks

C10 to C11

Carbonyl Compounds

Esters