ChemicalBook > CAS DataBase List > 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

Product Name
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
CAS No.
1479-24-9
Chemical Name
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
Synonyms
RMA-126;NSC 166423;ETHYL 2-FLUOROBENZOYLACETATE;Ethyl(2-Fluorobenzoyl)acetate>2-Fluorobenzoylacetic acid ethyl ester;2-[(2-fluorophenyl)-oxomethyl]butanoate;ETHYL 3-(2-FLUOROPHENYL)-3-OXOPROPANOATE;Ethyl 3-oxo-3-(2-fluorophenyl)propionate;Ethyl 3-(2-fluorophenyl)-3-oxo-propionate;Ethyl (2-fluorobenzoyl)acetate technical grade
CBNumber
CB7331507
Molecular Formula
C11H11FO3
Formula Weight
210.2
MOL File
1479-24-9.mol
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3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Property

Boiling point:
124-125℃ (1.5 Torr)
Density 
1.164 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.516(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
Liquid
pka
10.03±0.46(Predicted)
color 
Colorless to Light orange to Yellow
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Safety

WGK Germany 
3
HS Code 
2918.30.9000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
225134
Product name
Ethyl (2-fluorobenzoyl)acetate
Purity
technical grade
Packaging
1g
Price
$176
Updated
2023/06/20
Sigma-Aldrich
Product number
225134
Product name
Ethyl (2-fluorobenzoyl)acetate
Purity
technical grade
Packaging
10g
Price
$1090
Updated
2023/06/20
TCI Chemical
Product number
E1097
Product name
Ethyl (2-Fluorobenzoyl)acetate
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$114
Updated
2025/07/31
TCI Chemical
Product number
E1097
Product name
Ethyl (2-Fluorobenzoyl)acetate
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$398
Updated
2025/07/31
TRC
Product number
B124908
Product name
Ethyl3-(2-Fluorophenyl)-3-oxopropanoate
Packaging
100mg
Price
$60
Updated
2021/12/16
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3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Uses

Ethyl (2-fluorobenzoyl)acetate may be used in chemical synthesis.

Synthesis

64-17-5

223679-79-6

1479-24-9

GENERAL METHOD: An appropriate amount of diketone (9a or 9b) (0.3 mol) was mixed with ethanol (500 mL), heated to 80 °C and refluxed for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was removed by distillation under reduced pressure to give the target product ester (10a or 10b) in the form of a red oil. 7.10.1 Preparation of ethyl 3-(2-fluorophenyl)-3-oxopropanoate (10a): the product obtained was a red oily material in 85% yield; mass spectrum (ESI) m/z: 233.1 [M + Na]? , 443.1 [2M + Na]?

References

[1] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 11, p. 2843 - 2855
[2] Archiv der Pharmazie, 2013, vol. 346, # 7, p. 521 - 533
[3] Patent: EP2799437, 2014, A1. Location in patent: Paragraph 0057
[4] Patent: US2014/364431, 2014, A1. Location in patent: Paragraph 0188
[5] Patent: WO2017/37672, 2017, A1. Location in patent: Page/Page column 48

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER manufacturers

Career Henan Chemical Co
Product
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER 1479-24-9
Price
US $1.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
KG/T
Release date
2019-12-18

1479-24-9, 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTERRelated Search:

3-OXO-PROPIONIC ACID ETHYL ESTER 2-CYANO-3-(4-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Ethyl (3-fluorobenzoyl)acetate 2-CYANO-3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER 3-(2,4-DICHLORO-5-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER 3-(4-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Ethyl 2,4,5-trifluorobenzoylacetate 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Ethyl (pentafluorobenzoyl)acetate Ethyl 2,3,4,5-tetrafluorobenzoyl acetate 5,8-DIFLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 5,6,7,8-TETRAFLUORO-2-METHYL-4-OXO-4H-CHROMENE-3-CARBOXYLIC ACID ETHYL ESTER

  • Ethyl 3-oxo-3-(2-fluorophenyl)propionate
  • NSC 166423
  • Ethyl (2-fluorobenzoyl)acetate technical grade
  • Ethyl 3-(2-fluorophenyl)-3-oxo-propionate
  • 2-Fluorobenzoylacetic acid ethyl ester
  • 3-Oxo-3-(2-fluorophenyl)propionic acid ethyl ester
  • β-Oxo-2-fluorobenzenepropanoic acid ethyl ester
  • Benzenepropanoic acid, 2-fluoro-b-oxo-, ethyl ester
  • 2-[(2-fluorophenyl)-oxomethyl]butanoate
  • ETHYL 2-FLUOROBENZOYLACETATE
  • ETHYL 3-(2-FLUOROPHENYL)-3-OXOPROPANOATE
  • 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
  • Ethyl(2-Fluorobenzoyl)acetate&gt
  • Benzenepropanoic acid, 2-fluoro-β-oxo-, ethyl ester
  • RMA-126
  • Benzenepropanoic acid, 2-fluoro-β-oxo-, ethyl ester
  • 1479-24-9
  • Building Blocks
  • Carbonyl Compounds
  • C10 to C11
  • Organic Building Blocks
  • Esters
  • Aryl Fluorinated Building Blocks
  • Building Blocks
  • C10 to C11
  • C8-C12
  • Carbonyl Compounds
  • Chemical Synthesis
  • Fluorinated Building Blocks
  • Organic Building Blocks
  • Organic Fluorinated Building Blocks
  • Other Fluorinated Organic Building Blocks
  • C10 to C11
  • Carbonyl Compounds
  • Esters