ChemicalBook > CAS DataBase List > 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE
8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE
- Product Name
- 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE
- CAS No.
- 99295-33-7
- Chemical Name
- 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE
- Synonyms
- 159021;SKF 83566 hydrobromi;SKF 83566 HYDROBROMIDE;nicotine craving|||dorsal striatum|||Inhibitor;(+/-)-SKF-83566 HYDROCHLORIDE SELECTIVE DOPAMINE D1;8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol;1H-3-Benzazepin-7-ol, 8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-;7-bromo-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol hydrobromide;8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE;8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol hydrochloride
- CBNumber
- CB7334038
- Molecular Formula
- C17H18BrNO
- Formula Weight
- 332.23
- MOL File
- 99295-33-7.mol
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8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Property
- storage temp.
- Desiccate at RT
- solubility
- 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: ≥14 mg/mL
- form
- solid
- color
- light tan
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Tocris
- Product number
- 1586
- Product name
- SKF83566hydrobromide
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $115
- Updated
- 2021/12/16
Tocris
- Product number
- 1586
- Product name
- SKF83566hydrobromide
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $482
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- BRS0000210
- Product name
- SKF-83566
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $646.73
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0133715
- Product name
- SKF-83566
- Purity
- 99.86%
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0133715
- Product name
- SKF-83566
- Purity
- 99.86%
- Packaging
- 5mg
- Price
- $95
- Updated
- 2021/12/16
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8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Chemical Properties,Usage,Production
Uses
SKF 83566 Hydrobromide is a very potent and selective D1-like dopamine receptor antagonist, specifically at the 5-HT2 receptor.
Definition
ChEBI: 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol is a benzazepine.
Biological Activity
Potent and selective D 1 -like dopamine receptor antagonist (K i ~ 0.56 nM for D 1 ; K B = 2 μ M for D 2 ). Also antagonist at the vascular 5-HT 2 receptor (K i = 11 nM). Centrally active following systemic administration in vivo .
8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Suppliers
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